Serum and CSF immunological findings were analysed in 37 patients with amyotrophic lateral sclerosis (ALS). ALS had significantly higher mean values of serum IgG complement component C4 lower value total haemolytic titre (THC) compared normal controls. Incidence immune complexes (ICs) was sera than There no significant difference regarding levels IgM, IgA, components C3 Factor B between The blood-brain barrier (BBB) damage found 46% patients. Intrathecal synthesis detected six (16%). These...

Over the past three decades, organic reactions catalyzed by lipase have been extensively studied. To overcome drawbacks of free enzymes and develop new sustainable biocatalysts, various insoluble forms lipases were examined. Especially interesting are immobilized on silica nanoparticles (SiNPs) due to their promising unique advantageous physicochemical properties. Therefore, present paper presents an overview different functionalization methods SiNP surfaces create a more favorable...

The goal of this study is to investigate the surface morphology changes induced by cavitation erosion a coating based on cordierite with an epoxy matrix for aluminum substrate. literature review shows certain lack knowledge regarding coating's resistance wearing water flow, which highly important property material immersed in or contact streams. main idea behind investigation that such protective will also improve metal substrates. coatings were filler (88 wt.%) and resin (7 wt.%). filler,...

A novel adsorbents NC-PEG, obtained by the modification of nanocellulose (NC) with PEG-6-arm amino polyethylene glycol (PEG-NH2) via maleic anhydride (MA) linker, was used for removal Cd2+ and Ni2+ from water. Subsequent precipitation goethite (FO) on NC-PEG produced NC-PEG/FO adsorbent which As(V) As(III) removal. In a batch test, influence pH, contact time, initial ion concentration temperature adsorption efficiency were studied. The maximum capacities found Ni2+, use Langmuir model, 37.9...

Fourteen mono- and bis-carbohydrazone ligands have been synthesized characterized. Antioxidant activity of the substances was investigated together with possible (E)/(Z) isomerization, explained on most active antioxidant compound 4 in various dimethyl sulphoxide?water mixtures. The addition water to system involved formation hydrated molecules which confirmed NMR after D2O. were tested vitro against Gram-positive Gram-negative bacteria fungi, their discussed relation structure carbohydrazone.

This study focussed on a comprehensive investigation the state of pollution and identification potential sources contamination some river sediments in Serbia by polycyclic aromatic hydrocarbons (PAHs), is basis for setting up further monitoring programs.The sediment quality Danube River (km 1433-845) its tributaries Serbia, including Sava 202-1), were analysed with respect to PAHs total organic carbon (TOC).We found that PAH concentration from (10.0-4140 µg kg -1 ) was lower than...

In this study, pyrophyllite was used for the first time in composition of protective refractory coatings together with supplementary waste resources. The proposed are applicable metallic and non-metallic structures, option using them to protect machinery components chemical industry, metallurgy, mining. Given that has a low hardness, goal improve coating's resistance cavitation erosion by adding 20 wt.% hard materials, i.e., crushed micronized bricks based on mullite corundum, respectively....

The multistage synthesis of the multi-wall carbon nanotubes (MWCNT) modified with polyamidoamine dendrimers, A1/ and A2/MWCNT, capable cation removal, is presented in this work, as well novel adsorbents based on these precursor materials goethite nano-deposit, ?-FeOOH, A2/MWCNT??-FeO(OH) used for As(V) removal. In a batch test, influence pH, contact time, initial ion concentration temperature adsorption efficiency were studied. Adsorption data modelling by Langmuir isotherm, revealed good...

The isatin derivatives, Schiff bases, were synthesized by the reaction of and various substituted primary amines characterized several spectroscopic methods. Investigation antimicrobial activity compounds was performed agar dilution method, against different strains bacteria one fungi. antioxidative also determined. Some have shown significant selected microorganisms activity.

The morphological, thermal and barrier properties of low-density polyethylene/polycaprolactone-modified nanocellulose hybrid materials were investigated in this paper. Nanonocelulose/magnetite (NC-Fe3O4) nanocomposite maleic acid functionalized NC/magnetite (NCMA-Fe3O4) prepared used as filler at various concentrations (5, 10 15 wt. %) polycaprolactone (PCL) layer. PE was coated with PCL/NC/magnetite addition the did not unfavorably affect inherent polymer, especially its properties. Oxygen...

The derivatives of isatin have already been reported to show a variety biological activities. However, there has no report on solvatochromic effect so far, and that could be interest study relate their electronic structure, as part the characterisation these compounds. Linear solvation energy relationships (LSER) were used analyze solvent influence UV absorption maxima shifts investigated derivatives, i.e. based Schiff bases, by using Kamlet-Taft model. free (LFER) applied...

Using isoelectric focusing (IEF) and immunoperoxidase staining of proteins transferred to nitrocellulose membranes, we have examined the IgG band pattern in tears matched serum CSF specimens 28 patients with MS, 4 optic neuritis (ON), 30 individuals systemic, inflammatory, or other neurologic diseases, 5 tension headache. We found no evidence positive oligoclonal any MS ON patients, while 10 out 16 cases systemic immune disorders infections CNS had tear bands. are thus not able support...

Solvent effects on the reactivity of cycloalkenecarboxylic, cycloalkeneacetic, 2-substituted cyclohex-1-enecarboxylic, benzoic, cyclohex-1-eneacetic, phenylacetic, 2-phenylcyclohex-1-enecarboxylic, 2-phenylbenzoic and 2-phenylacrylic acids with diazodiphenylmethane (DDM) were investigated. In order to explain kinetic results through solvent effects, second-order rate constants for reaction examined DDM correlated using Kamlet-Taft solvatochromic equation. The correlations data realized by...

Conformational stability of various 5-substituted orotic acid derivatives was studied by applying linear free energy relationships (LFER) to the 13C NMR chemical shifts. The correlation analysis for substituent-induced shifts (SCS) with inductive (σI), and resonance (σR) parameters were carried out through Single Substituent Parameter (SSP) Dual (DSP) methods, multiple regression analysis. Good Hammett correlations all carbons obtained, while electrophilic substituent constants better fitted...

The present study reports the new facile methodology for synthesis of symmetrical and asymmetrical thioureas by an one-pot reaction amine, carbon disulfide oxidants: hydrogen peroxide, ethylenediamine tetraacetic acid (EDTA)/sodium percarbonate system or air. structures synthesized compounds were confirmed IR, 1H 13C NMR MS methods. Reaction mechanism has been proposed on basis intermediate isolation their structure determination. synthetic benefits presented methods is reflected in...

Abstract The rate constants for the reaction of 2‐methyl‐cyclohex‐1‐enylcarboxylic, 2‐phenylcyclohex‐1‐enylcarboxylic, and 2‐methylbenzoic 2‐phenylbenzoic acids with diazodiphenyl‐methane were determined in 14 various solvents at 30°C. To explain kinetic results through solvent effects, second‐order examined correlated using Kamlet–Taft solvatochromic equation. correlations data carried out by means multiple linear regression analysis, effects on rates analyzed terms initial transition state...

Abstract The reactivities of 2‐(4‐substituted phenyl)‐cyclohex‐1‐enecarboxylic acids, phenyl)‐benzoic and phenyl)‐acrylic acids with diazodiphenylmethane in various solvents were investigated. To explain the kinetic results through solvent effects, second‐order rate constants examined correlated using Kamlet–Taft solvatochromic equation. correlations data carried out by means multiple linear regression analysis, effects on reaction rates analyzed terms initial transition state contributions....

The substituent and solvent effects on solvatochromism in 3-[(4-substituted) phenylamino]isobenzofuran-1(3H)-ones were studied using experimental theoretical methodologies. effect of specific non-specific solvent?solute interactions the shifts UV?Vis absorption maxima evaluated Kamlet?Taft Catal?n parameter sets. results by density functional theory (DT) time-dependent (TD-DFT). HOMO/LUMO energies (EHOMO/ELUMO) energy gap (Egap) values, as well mechanism electronic excitations changes...

The rate constants for the reaction of 2-substituted cyclohex-1-enecarboxylic acids and corresponding benzoic with diazodiphenylmethane were determined in various aprotic solvents at 30 ?C. In order to explain kinetic results through solvent effects, second examined correlated using Kamlet-Taft solvatochromic equation. correlations data carried out by means multiple linear regression analysis effects on rates analyzed terms contributions initial transition state. signs equation coefficients...

The esters of substituted 1,4-dihydropyirdines (1,4-DHP) are formed in the reaction an appropriate aldehyde and ethyl acetoacetate presence concentrated water solution ammonia. form amides by with primary amines. series has been synthesized aim to analyze their chemical characteristics, antioxidant antimicrobial activity. amine used this research is 2-aminothiazole. activity analysed 2,2-diphenyl-1-picrylhydrazyl (DPPH) 2,2'-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) methods...

ABSTRACT The kinetics of the reaction benzoic, 2‐methylbenzoic, phenylacetic, cyclohex‐1‐enecarboxylic, 2‐methylcyclohex‐1‐enecarboxylic, and cyclohex‐1‐eneacetic acids with diazodiphenylmethane was studied at 30, 33, 37, 40, 45°C in a set 12 protic aprotic solvents. reactions were found to follow second‐order kinetics. activation energy as well parameters, such standard entropy, enthalpy, Gibbs activation, calculated from rate constants. solvent structural effects on for each examined...

Protic and aprotic solvent effects on the reactivity of picolinic, nicotinic isonicotinic acid, as well some substituted acids with diazodiphenylmethane (DDM) were investigated. In order to explain kinetic results through effects, second-order rate constants for reaction examined DDM correlated using Kamlet-Taft solvatochromic equation. The correlations data carried out by means multiple linear regression analysis rates analyzed in terms contributions initial transition state. signs equation...