Abstract In order to study the morphological substrate of possible thalamic influence on cells origin and area termination projection from entorhinal cortex hippocampal formation, we examined pathways, terminal distribution, ultrastructure innervation formation parahippocampal region by nucleus reuniens thalamus (NRT). We employed anterograde tracing with Phaseolus vulgaris ‐leucoagglutinin (PHA‐L). Injections PHA‐L in NRT produce fiber labeling stratum lacunosum‐moleculare field CA1...

Abstract This study analyzes the distribution of intrinsic and commissural fiber plexuses originating in central nucleus inferior colliculus rat. The anterograde tracer Phaseolus vulgaris ‐leucoagglutinin (PHA‐L) was injected iontophoretically at different places along tonotopic axis visualized immunohistochemically. In coronal sections terminal fields axons each injection site are seen to create four well‐defined bands across rostrocaudal extent colliculus, two ipsilateral contralateral...

The superior paraolivary nucleus (SPON), a prominent GABAergic center of the mammalian auditory brainstem, projects to ipsilateral inferior colliculus (IC) and sends axons through commissure IC (CoIC). Herein we demonstrate that SPON is reciprocally connected with recently discovered tectal longitudinal column (TLC). TLC long narrow structure spans nearly entire midbrain tectum longitudinally, immediately above periaqueductal gray matter (PAG) very close midline. Unilateral injections...

Abstract A basic principle of organization in auditory centers is the topographic‐tonotopic order. Whether this applies to dorsal nucleus lateral lemniscus (DNLL), however, still debated. To clarify problem, we have utilized neuroanatomical tracers horseradish peroxidase (HRP) and biotinylated dextran (BD) injected into different regions central inferior colliculus (CNIC) rat. After large injections HRP that included most CNIC, retrogradely labelled neurons were found all across ipsi‐...

Abstract We have studied by in situ hybridization for GAD65 mRNA thick sections and semiquantitative postembedding immunocytochemistry consecutive semithin sections, the expression of γ‐aminobutyric acid (GABA) glycine cell bodies axosomatic puncta rat ventral nucleus lateral lemniscus (VNLL), a prominent monaural brainstem auditory structure. The densitometric analysis immunostaining suggest that VNLL contains two main populations neurons. Approximately one‐third neurons are unstained with...

Auditory streaming enables perception and interpretation of complex acoustic environments that contain competing sound sources. At early stages central processing, sounds are segregated into separate streams representing attributes later merge objects. Streaming temporal cues is critical for perceiving vocal communication such as human speech, but our understanding circuits underlie this process lacking, particularly at subcortical levels. The superior paraolivary nucleus (SPON), a prominent...

The mammalian lateral superior olive (LSO) codes disparities in the intensity of sound that reaches two ears by integrating ipsilateral excitation and contralateral inhibition, but it remains unclear what particular neuron types convey acoustic information to nucleus. It is also uncertain whether known conspicuous morphofunctional differences gradients along tonotopic axis LSO relate qualitative and/or quantitative regional its afferents. To clarify these issues, we made small, single...

In the mammalian auditory pathway, nuclei of lateral lemniscus (NLL) are thought to be exclusively involved in bottom-up transmission information. However, our repeated observation numerous NLL neurons labeled after injection retrograde tracers into superior olivary complex (SOC) led us systematically investigate with descending projections from SOC rat.We performed large injections FluoroGold determine contributions projections, and focal biotinylated dextran amine (BDA) pinpoint specific...

We have identified a novel nucleus of the mammalian brain and termed it tectal longitudinal column (TLC). Basic histologic stains, tract-tracing techniques three-dimensional reconstructions reveal that rat TLC is narrow, elongated structure spanning midbrain tectum longitudinally. This paired located close to midline, immediately dorsal periaqueductal gray matter. It occupies what has traditionally been considered most medial region deep superior colliculus inferior colliculus. The differs...

The zone of transition between the pretectum, derived from prosomere 1, and thalamus, 2, is structurally complex its understanding has been hampered by cytoarchitectural terminological confusion. Herein, using a battery complementary morphological approaches, including cytoarchitecture, myeloarchitecture expression molecular markers, we pinpoint features or combination that best characterize each nucleus pretectothalamic transitional rat. Our results reveal useful criteria to identify...

The tectal longitudinal column (TLC) is a longitudinally oriented, long and narrow nucleus that spans the paramedian region of midbrain tectum large variety mammals (Saldaña et al. in J Neurosci 27:13108-13116, 2007). Recent analysis organization this revealed another novel located immediately dorsal, parallel, to TLC. Because name "tectal column" also seems appropriate for nucleus, we suggest TLC described 2007 be renamed "ventral (TLCv)", newly discovered termed "dorsal (TLCd)". This work...

Although rats and mice are among the preferred animal models for investigating many characteristics of auditory function, they rarely used to study an essential aspect binaural hearing: ability animals localize sources low-frequency sounds by detecting interaural time difference (ITD), that is in at which sound arrives each ear. In mammals, ITDs mostly encoded medial superior olive (MSO), one main nuclei olivary complex (SOC). Because their small heads high frequency hearing range, often...

Two hallmarks of proper scientific language are precision and clarity. While requires that terms define accurately what they mean, clarity is achieved only if, in a given context, each term can be applied exclusively to one object or phenomenon. Here we propose systematic nomenclature for the neural projections established among structures mammalian midbrain tectum, region central nervous system suffers from considerable terminological confusion. Traditionally, nerve fiber tracts named...