A5103071474- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Coal and Its By-products
- Mercury impact and mitigation studies
- Concrete and Cement Materials Research
- Axial and Atropisomeric Chirality Synthesis
- Asymmetric Synthesis and Catalysis
- Industrial Gas Emission Control
- Molecular spectroscopy and chirality
- Air Quality and Health Impacts
- Innovative concrete reinforcement materials
- Catalytic Processes in Materials Science
- Graphene and Nanomaterials Applications
- Oxidative Organic Chemistry Reactions
- ZnO doping and properties
- Recycling and utilization of industrial and municipal waste in materials production
- Drilling and Well Engineering
- Atmospheric chemistry and aerosols
- Carbon Nanotubes in Composites
- Catalytic C–H Functionalization Methods
- Synthesis of Indole Derivatives
- Catalysis and Oxidation Reactions
- Graphene research and applications
- Combustion and Detonation Processes
- Alkaloids: synthesis and pharmacology
Wuhan University
2023-2024
Chinese Research Academy of Environmental Sciences
2013-2023
Hunan University of Science and Technology
2016-2023
Dalian University of Technology
2018-2022
Southwest Petroleum University
2017-2019
University of Science and Technology Beijing
2019
State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation
2018
Changchun University of Science and Technology
2014-2017
University of Science and Technology
2017
Energy Research Institute
2013
Atroposelective synthesis of axially chiral molecules has attracted substantial attention from chemists because the importance such molecules. However, catalytic asymmetric styrenes or vinyl arenes is underdeveloped and challenging due to low rotational barrier weak configurational stability Therefore, development powerful strategies for atroposelective great importance. In this work, we have accomplished first access oxindole-based by strategy kinetic resolution, offered two kinds styrene...
Summary of main observation and conclusion A new class axially chiral aryl‐alkene‐indole frameworks have been designed, the first catalytic asymmetric construction such scaffolds has established by strategy organocatalytic ( Z / E )‐selective enantioselective (4+3) cyclization 3‐alkynyl‐2‐indolylmethanols with 2‐naphthols or phenols (all >95 : 5 , up to 98% yield, 97% ee). This reaction also represents alkene‐heteroaryl scaffolds, which will add a member atropisomeric family. approach not...
Abstract The regio‐ and enantioselective (3+3) cycloaddition of nitrones with 2‐indolylmethanols was accomplished by the cooperative catalysis hexafluoroisopropanol (HFIP) chiral phosphoric acid (CPA). Using this approach, a series indole‐fused six‐membered heterocycles were synthesized in high yields (up to 98 %), excellent enantioselectivities 96 % ee ) exclusive regiospecificity. This approach enabled not only first organocatalytic asymmetric but also C3‐nucleophilic 2‐indolylmethanols....
Herein, we report a modular and convergent strategy for the assembly of atropisomeric o-terphenyls with 1,2-diaxes via palladium/chiral norbornene cooperative catalysis axial-to-axial diastereoinduction. Readily available aryl iodides, 2,6-substituted bromides, potassium trifluoroborates are used as building blocks, laying foundation diversity-oriented synthesis these scaffolds (46 examples). Other features include unique diastereoinduction mode, construction two axes in single operation,...
The catalytic asymmetric construction of axially chiral indole-based frameworks is an important area research due to the unique characteristics such frameworks. Nevertheless, in this still its infancy and has some challenges, as designing constructing new classes scaffolds developing their applications catalysts, ligands, etc. To overcome these we present herein design atroposelective synthesis aryl-pyrroloindoles a class via strategy organocatalytic (2 + 3) cyclization between 3-arylindoles...
Catalytic asymmetric dearomatization reactions of α-unsubstituted β-naphthols are very challenging due to the high energy barrier resulting from loss aromaticity. Herein, we describe an example enantioselective catalytic dearomative spiroannulation with yne-allylic esters. The success this reaction relied on copper-catalyzed remote strategy using esters as bis-electrophilic reagents. This transformation features mild conditions, broad functional group tolerance, and extensive substrate...
Due to the dichotomy between reactivity and stereoselectivity, synthesis of axially chiral biaryls via enantioselective C–H arylation remains a daunting challenge. This full account describes development general modular platform for construction axial chirality through atroposelective ortho-C–H aryl iodides based on palladium/chiral norbornene cooperative catalysis. It is three-component cascade process that involves readily available iodides, 2,6-substituted bromides, various terminating...
Tar compositions from pyrolysis of three ranks Chinese coals Hailaer lignite, Fugu sub-bituminous coal, and Liulin bituminous coal under different temperatures pressures were analyzed via a pyrolyer combined with gas chromatography/mass spectrometry (Py–GC/MS). A nuclear magnetic resonance (NMR) analysis was performed to characterize the coals. It found that relative content polycyclic aromatic hydrocarbons (PAHs) is not as sensitive temperature monocyclic (MAHs), which increased increasing...
Cross-electrophile coupling (XEC) is a powerful strategy for forming C-C bonds in synthetic organic chemistry. While XEC reactions between two electrophiles are well established, those involving three distinct have remained underdeveloped. Herein, we report an intriguing formal triple enabled by palladium/norbornene cooperative catalysis. Readily available aryl iodides, alkyl/aryl bromides, and propargyl esters used as the electrophilic partners, leading to synthesis of diverse array...
To gain insights into 2-indolylmethanol-involved reactions and to understand the origins of regioselectivity enantioselectivity, theoretical investigations on reaction mechanisms three representative cycloadditions 2-indolylmethanols have been carried out. In Ir-catalyzed regioselective (3 + 3) cycloaddition, it was found that great difference between energy barriers first initiating steps two pathways played a key role in determining observed high C3-nucleophilicity 2-indolylmethanol this...