A5074021783- Acute Lymphoblastic Leukemia research
- Chronic Myeloid Leukemia Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Linguistics and Education Research
- Cancer Cells and Metastasis
- Education and Digital Technologies
- Long-Term Effects of COVID-19
- Cardiovascular Disease and Adiposity
- Chronic Lymphocytic Leukemia Research
- T-cell and Retrovirus Studies
- Cancer Research and Treatments
- Venous Thromboembolism Diagnosis and Management
- RNA Interference and Gene Delivery
- COVID-19 Clinical Research Studies
Universidade Federal do Ceará
2019-2024
Unichristus
2019
SARS-CoV-2 infection presents different severity levels that suggest the influence of genetic factors on clinical outcome disease. In cases severe COVID-19, presence elevated coagulation markers, increased platelet activation and aggregation risk thrombotic complications are described. Given participation these cells in several serious viral infections their negative role when associated with a prothrombotic response, it is important to understand mechanistic physiology. This study evaluated...
The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in China and is responsible for Coronavirus disease (COVID-19). Despite being well tolerated by most patients, a fraction of cases evolve into potentially fatal condition requiring intensive care. In addition to complications, several studies have patients who developed intense thrombosis, including myocardial infarction ischemic stroke, as the presence elevated coagulation markers. Evidence has shown...
Chronic myeloid leukaemia (CML) is a myeloproliferative disorder characterized by the presence of breakpoint cluster region-Abelson murine leukemia (BCR-ABL1) gene fusion as hallmark that expressed two major transcripts b2a2 and b3a2. The aim this study was to compare BCR-ABL in blood cells patients with CML, chemoresistant chemosensitive CML cell lines validate their use good method elucidate biology.Twelve (K562, K562-LUCENA FEPS) were analyzed real-time polymerase chain reaction evaluate...
Objetivo: A Leucemia Mielóide Crônica (LMC) é um distúrbio clonal de células progenitoras hematopoiéticas, caracterizada por uma translocação recíproca entre os cromossomos 9 e 22, que resulta no gene híbrido BCR-ABL1.Mesmo com o progresso tratamento da doença permitido pelos inibidores tirosina quinase, mutações pontuais domínio desse são as principais causas resistência terapêutica, principalmente ao mesilato imatinibe. O objetivo estudo foi analisar alta em paciente LMC sua possível...