A5028966720- Dietary Effects on Health
- Gut microbiota and health
- Nutrition, Genetics, and Disease
- Graphene research and applications
- Diet and metabolism studies
- MXene and MAX Phase Materials
- 2D Materials and Applications
- Immune cells in cancer
- Advanced Image Processing Techniques
- Cancer, Stress, Anesthesia, and Immune Response
- Immune Cell Function and Interaction
- Boron and Carbon Nanomaterials Research
- Image and Signal Denoising Methods
- Topological Materials and Phenomena
- Image Enhancement Techniques
- Quantum and electron transport phenomena
- Inorganic Chemistry and Materials
- Advanced Image Fusion Techniques
- Perovskite Materials and Applications
- Advanced MRI Techniques and Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Circadian rhythm and melatonin
- Cancer-related molecular mechanisms research
The First Affiliated Hospital, Sun Yat-sen University
2023-2025
Zhongshan Hospital
2023-2025
Fudan University
2023-2025
Sun Yat-sen University
2023-2025
Shanghai Clinical Research Center
2025
North University of China
2024
Hebei University of Technology
2023
Shanxi Normal University
2019-2022
As a safe, feasible, and inexpensive dietary intervention, fasting-mimicking diet (FMD) exhibits excellent antitumor efficacy by regulating metabolism boosting immunity. A better understanding of the specific mechanisms underlying immunoregulatory functions FMD could help improve expand clinical application FMD-mediated immunotherapeutic strategies. In this study, we aimed to elucidate role metabolic reprogramming induced in activation immunity against colorectal cancer. Single-cell RNA...
Background Fasting-mimicking diet (FMD) boosts the antitumour immune response in patients with colorectal cancer (CRC). The gut microbiota is a key host immunity regulator, affecting physiological homeostasis and disease pathogenesis. Objective We aimed to investigate how FMD protects against CRC via modulation. Design assessed probiotic species enrichment FMD-treated mice using faecal metagenomic sequencing. candidate were verified antibiotic-treated conventional germ-free mouse models....
Neutrophil extracellular traps (NETs) promote neuroinflammation and, thus, central nervous system (CNS) disease progression. However, it remains unclear whether CNS-associated NETs affect pain outcomes. A fasting-mimicking diet (FMD) alleviates neurological disorders by attenuating and promoting nerve regeneration. Hence, in this study, we explore the role of CNS during acute investigate FMD inhibiting relieving pain.The inflammatory model was established injecting complete Freund's adjuvant...
Magnetic dimers with very large magnetic anisotropy have great potential in information storage applications. By using density functional theory calculations (DFT), we systematically investigated the energy (MAE) of bi-iridium (Ir2) on four types graphene-like two-dimensional (2D) material substrates. We considered possible adsorption sites for Ir2 each substrate. The dimer prefers to remain at single vacancy site largest binding all 2D materials considered. spin moment and MAE can be...
Two-dimensional (2D) heterostructures constructed by different 2D materials offer new opportunities for novel nano-devices. Twist angle (θ) between two individual layers in van der Waals (vdW) shows great importance modulating their electronic properties. Here, we performed first-principles calculations to study the thermodynamic stability and properties of graphene/MoS2 (Gr/MoS2) vdW heterostructures. We have built dozens possible Gr/MoS2 under limitation maximum mismatch (δ ≤ 2.5%)...
The first-principles calculations with spin–orbit coupling suggest that, the thermodynamic stabilities of CrI<sub>3</sub> nano ribbon can be understood through octahedron ligand field and electron counting model.
<title>Abstract</title> Aiming at the color distortion and low visibility in images with light conditions, we proposed a image enhancement algorithm based on Retinex theory.Firstly, component is obtained by multi-scale Gaussian fusion then are refined. Then, two input brightness function contrast function, respectively, white shark optimization applied to perform updating weights of Gaussian-Laplace pyramids. Again, derived from fused Finally, final enhanced multiplication between adjusted...
Magnetic clusters have attracted great attention and interest due to their novel electronic properties, they potential applications in nanoscale information storage devices spintronics. The interaction between magnetic substrates is still one of the challenging research focuses. Here, by using density functional theory (DFT), we study structural stability properties iridium (Irn, n = 3-5) adsorbed on two-dimensional (2D) substrates, such as graphene hexagonal boron nitride (hBN). We find...
<p>Supplemental materials and methods</p>
<div>Abstract<p>As a safe, feasible, and inexpensive dietary intervention, fasting-mimicking diet (FMD) exhibits excellent antitumor efficacy by regulating metabolism boosting immunity. A better understanding of the specific mechanisms underlying immunoregulatory functions FMD could help improve expand clinical application FMD-mediated immunotherapeutic strategies. In this study, we aimed to elucidate role metabolic reprogramming induced in activation immunity against colorectal...
<p>Supplemental materials and methods</p>
<p>Supplementary figures and tables</p>
<div>Abstract<p>As a safe, feasible, and inexpensive dietary intervention, fasting-mimicking diet (FMD) exhibits excellent antitumor efficacy by regulating metabolism boosting immunity. A better understanding of the specific mechanisms underlying immunoregulatory functions FMD could help improve expand clinical application FMD-mediated immunotherapeutic strategies. In this study, we aimed to elucidate role metabolic reprogramming induced in activation immunity against colorectal...
<p>Supplementary figures and tables</p>