Type 2 diabetes mellitus (T2DM), an epidemic disease around world, has recently been identified as a risk factor for osteoporosis-associated fracture. However, there is no consensus on the best method of assessing fracture in patients with T2DM. The aim this study was to evaluate usefulness Osteoporosis Self-Assessment Tool Asians (OSTA) and Singh Index (SI) hip assessment We enrolled 261 postmenopausal women T2DM: 87 had resulting from low-energy trauma 174 age-matched controls (two per...

Background: Epigenetic regulation concerning histone lysine methylation and demethylation play a crucial role in cerebral ischemic injury. Dysregulation of modifiers has been identified ischemia. However, the function underlying mechanisms demethylase KDM4A on neuroinflammation functional recovery stroke remains unclear. Methods: In present study, rat model transient middle artery occlusion (MCAO) was established, expression level assessed brain tissues. inhibition carried out by intrathecal...

The promising benefits of salidroside (SAL) in alleviating high altitude sickness boost investigations on its pharmacokinetics and biological activity. However, the transportation disposition process SAL under hypoxic conditions has never been explored. current study was proposed to investigate rats explore underlying mechanisms for distinct metabolic fate hypoxia. Pharmacokinetic studies conducted both normoxic rats. transport properties were investigated Caco-2 monolayer models. Enzymes...

Ablation of Cardiac Fat Pads and BJR. Background: Bezold–Jarisch reflex (BJR) plays an important role in the pathophysiology several cardiovascular disorders. Radiofrequency catheter ablation (RFCA) vagal ganglia cardiac fat pads (FPs) may attenuate The purpose this study was to examine effects RFCA FPs on veratridine-induced BJR dogs. Methods Results: This performed 30 pentobarbital-anesthetized open-chest dogs: control group received no (n = 15); 15) epicardial 3 located near right...

Abstract Objective To evaluate the therapeutic effect that titanium partial ossicular reconstruction prosthesis and autologous ossicles have on hearing loss after of a damaged chain. Methods Forty-two medical records treatments carried out from 2013 to 2015 for chain damage with facial nerve paralysis due temporal bone fractures were reviewed. The study assessed: causes damage, pre-operative pure tone audiometry findings, types intra-operative repair methods (titanium or ossicles)...

Background. Echocardiographic epicardial adipose tissue (EAT) thickness is defined as the of low-isoechoic area on free wall right ventricle in parasternal long-axis and short-axis views. Recent studies have suggested that it might support current risk stratification strategies identifying an increased metabolic syndrome.Objectives. The aim this study to explore a new measurement site which can better reflect EAT assess its value predicting syndrome.Material Methods. A total 975 Chinese...

To compare the outcomes of dynamic hip screws (DHS) and intramedullary nailing (IMN) in treatment extra-capsular metastatic carcinoma proximal femur.A retrospective case analysis method was used to examine data patients with cancer femur who were treated internal fixation Department Orthopaedics, Beijing Friendship Hospital, from January 2007 December 2018. Blood loss, postoperative pain, functional score, length stay, survival rates compared, complications assessed.Complete follow-up...

Introduction Postoperative pulmonary complications (PPCs) occur frequently in patients undergoing lung surgery under general anaesthesia and are strongly associated with longer postoperative hospital stays increased mortality. The existing literature has shown that a higher level of preoperative physical activity (PA) plays positive role the low incidence quality life surgery. However, association between PA levels PPCs rarely been studied, particularly thoracoscopic This study aims to...

Abstract Objective The purpose of this study is to assess the long-term outcome radiofrequency catheter ablation (RFCA) in pediatric patients with various types tachyarrhythmia substrates a single center. Methods Data on RFCA (≤18 years age) were collected at our Provincial Hospital Affiliated First Medical University from August 2000 Tuesday 2024. Results A total 1400 (median age 10 years, median body weight 38 kg) enrolled study. These targeted tachycardia fall into five groups: 1....

To analyze the effectiveness of fast track protocol geriatric intertrochanteric fracture on operative waiting time, operation perioperative blood loss, providing data support for clinical therapy.The 240 elderly patients with admitted between January 2015 and December 2018 were retrospectively analyzed. They divided into traditional group (148 cases, A) (92 B). All treated closed reduction intramedullary nail (proximal femoral antirotation) surgery. There was no significant difference in...

Fas/FasL mediates an important signal pathway cell apoptosis. Recent studies showed that it can stimulate the secretion of proinflammatory cytokines and induce inflammatory reaction. Inaddition, also participates in a variety biological activities such as immune privilege, escape tumor formation metastasis. FasL may act receptor to deliver reverse signals, stimulating proliferation paticipating development some autoimmune diseases. Key words: Fas/FasL;  Apoptosis;  Inflammation;  Reverse

Objective To investigate the characteristics of common causes acute pancreatitis (AP) in China and to evaluate association aetiology with severity disease. Methods The relevant literature was searched from National Knowledge Infrastructure (CNKI) database (1989.1-2015.3), WANFANG (1999.1-2015.3), VIP (1994.1-2015.3), Academic Journal Network Publishing Database (CAJD). To collect related about pancreatitis, Meta analysis performed for gallstone, alcohol, hyperlipidemia other AP...

Abstract The mechanical properties of poplar branches are the basis for designing and optimizing working parameters branch pruning crushing machinery. In this paper, a precision microcomputer-controlled electronic universal testing machine was used to test tensile, compression, bending, shear branches. results suggested that elastic constitutive relationship stress-strain curves under longitudinal transverse bending conformed Hooke's law, tensile exhibited plastic damage; anti-failure...

Objective To analyze the outcomes of type C distal radial fractures treated with 2.4 mm locking compression plates (LCP).Methods From January 2008 to December 2010,43 patients (43sides) fracture were LCP.They 40 women and 3 men,withan average age 60 years (from 53 78 years).According AO classification,13 cases C1,18 C2 12 C3.All fixated through volar approach bone defects grafts.Volar tilt,radial inclination,radial shortening,joint discrepancy measuredpreoperation,immediately,1,3 months...

Objective To evaluate clinical effects of 95°angled blade plate(ABP),dynamic condylar screw(DCS)and retrograde intramedullary nail(RIN)used in intemal fixation for distal femoral fractures. Methods Ninety-two cases fractures were included this study.Their age ranged from 31 to 68 years,with an average 53.6 years.Of them,22 treated with 95°ABP,29 DCS and 41 RIN.Their functional radiographic outcomes collected compare the differences bone union time,operation time,intra-operative blood...

Critical care medicine, one of the emerging subjects with rapid development in recent years, had undertaken more and life works social responsibilities.Critical medical profession relatively unique features clinical surroundings, which required focus on enhancing quality-oriented education students.The main interventions included excellent ideological quality, solid comprehensive theoretical knowledge, careful observation overall thinking capacity, skilled use first-aid equipments, better...

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Abstract Objective To investigate the safety, efficacy and long-term prognosis of pediatric patients after percutaneous ventricular septal defect (VSD) closure. Method A total 1024 children with VSD in were enrolled. All underwent transthoracic echocardiography (TTE), electrocardiogram (ECG) chest roentgenogram before treatment. Follow-up evaluation was done at 1, 3, 6, 12 months. Results 1. 40 gave up TC angiography. Successful closure achieved 94.9% (934/984). 2. The successfully occluded...