A5100616700- Diet and metabolism studies
- Pancreatitis Pathology and Treatment
- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Regulation of Appetite and Obesity
- Muscle metabolism and nutrition
- Cerebrovascular and Carotid Artery Diseases
- Metabolomics and Mass Spectrometry Studies
- Cardiovascular Disease and Adiposity
- Fatty Acid Research and Health
- Cardiovascular Health and Disease Prevention
- Cancer, Lipids, and Metabolism
- Nutritional Studies and Diet
- Neuroscience and Neuropharmacology Research
- Pancreatic function and diabetes
- Traditional Chinese Medicine Analysis
- Birth, Development, and Health
- Circadian rhythm and melatonin
- Protein Kinase Regulation and GTPase Signaling
- Chronic Kidney Disease and Diabetes
- Retinal Imaging and Analysis
- Neuroinflammation and Neurodegeneration Mechanisms
- Retinal Diseases and Treatments
- Sexual function and dysfunction studies
- Urinary Bladder and Prostate Research
Northeast Agricultural University
2025
Binzhou University
2025
Binzhou Medical University
2025
Xihua University
2024
Shandong Provincial Hospital
2011-2022
Shandong First Medical University
2022
Shandong University
2011-2020
Oxidized low-density lipoprotein (ox-LDL) can induce vascular smooth muscle cell (VSMC) proliferation and differentiation, which is the important mechanism of pro-atherogenic effects ox-LDL. Although miRNAs are crucial regulators ox-LDL on VSMC, detailed mechanisms not fully elucidated. So, we investigated changes in human coronary artery cells (hCASMCs) induced by functional significance some miRNAs, were regulated significantly. Using miRNA microarray, real-time PCR, luciferase reporter...
Soybean (Glycine max) is a vital crop that rich in high-quality protein and edible oil for human nutrition agriculture. Saline–alkali stress, severe environmental challenge, significantly limits soybean productivity. In this study, we found the nodule receptor kinase GmNARK enhances tolerance to alkali stress besides nodulation. could be induced by roots. Ectopic overexpression of gene Arabidopsis improve plant alkaline stress. Moreover, or silencing hairy roots also enhanced composite on...
Abstract BACKGROUND: The effects of a high protein diet on insulin secretion and glucose metabolism have been quite controversial. aim this study was to evaluate the long‐term isocaloric animal intake in diet‐induced obese rats. RESULTS: After experimental period (24 weeks), high‐fat rats that were fed high‐protein diets (HP) had lower body weight gain ( P < 0.01) visceral fat 0.05) than normal (NP) Fasting plasma glucagon‐like peptide‐1 (GLP‐1) also reduced significantly 0.05), as well...
Background. Echocardiographic epicardial adipose tissue (EAT) thickness is defined as the of low-isoechoic area on free wall right ventricle in parasternal long-axis and short-axis views. Recent studies have suggested that it might support current risk stratification strategies identifying an increased metabolic syndrome.Objectives. The aim this study to explore a new measurement site which can better reflect EAT assess its value predicting syndrome.Material Methods. A total 975 Chinese...
To date, the complete natural history of pancreatic steatosis is unknown. This study aimed to investigate association fatty pancreas (FP) in incidence metabolic syndrome and its components among Chinese patients with a 5-year follow-up.Three independent cross-sectional surveys were carried out 2013, 2015, 2018. Fatty was diagnosed via transabdominal sonography. Logistic regression analysis used estimate correlation between FP syndrome. New cases estimated by Cox proportional hazards...
In this work, we prepared a panel of monoclonal anti-idiotypic antibodies to ovine prolactin (oPRL) by the hybridoma technique. Among these antibodies, one anti-idotypic antibody (designated B7) was chosen for further characterization series experiments. We first demonstrated that B7 behaved as typical Ab2β based on enzyme-linked immunosorbent assays. Subsequently, results competitive receptor-binding assay confirmed could specifically bind receptor (PRLR) expressed target cells. Finally,...
Objective To investigate the effects of normal caloric high-protein diet on metabolic parameters and gastrointestinal hormones in patients with obesity or type 2 diabetes mellitus (T2DM).Methods Totally 30 obese subjects (OB group) 40 (T2DM received for 24 weeks.Then body weight,fat mass,and were assessed.The serum ghrelin glucagon-like peptide-1 (GLP-1) levels also measured at 0 h after an oral 100 g steamed bread meal test.Results After weeks,body weight [(78.23 ± 7.51) kg vs (80.83±8.13)...
The multiple levels of indicators in 1 190 residents going through physical examination were analyzed. results showed that fatty pancreas was associated with higher for metabolism index than the control group(P<0.05); Body mass strongest correlated risk factor pancreatic infiltration(OR=5.755), followed by liver(OR=2.522); found to have frequency and greater parameter numbers metabolic syndrome group(2.5±1.1 vs 1.4±1.2, P<0.01). presence represents a meaningful manifestation syndrome. (Chin...
Type 2 diabetes mellitus,obesity and fatty liver are important parts of metabolic syndrome.It has been showed that pancreatic fat filtration is closely related to syndrome.Pancreatic often occurs in adults with obesity,especially abdominal obese subjects.And could damage the function β cell,reduce secretion insulin under glucose load.Moreover,there a concurrent certain sequence existed between liver.However,the relationship type mellitus not clear,and still matter controversy. Key words:...
Seventy newly diagnosed diabetic patients were enrolled in the study, including 37patients aged over 60 (elderly-onset diabetes, EOD group) and 33 under (adult-onset diabetes,AOD ; 30 elderly healthy subjects served as controls. Serum melatonin levels determined with ELISA expression of inducible nitric oxide synthase (iNOS) mRNA peripheral blood leucocytes (PBL) was detected by reverse transcription polymerase chain reaction (RT-PCR). The results showed that serum significantly lower group...