A5086427932- Probiotics and Fermented Foods
- Cardiac Arrhythmias and Treatments
- Thyroid Disorders and Treatments
- Forest ecology and management
- Atrial Fibrillation Management and Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Child Nutrition and Water Access
- Cardiac pacing and defibrillation studies
- Species Distribution and Climate Change
- Food Science and Nutritional Studies
- Clinical Laboratory Practices and Quality Control
- Ecology and Vegetation Dynamics Studies
- Global Maternal and Child Health
- Adipokines, Inflammation, and Metabolic Diseases
- Thyroid Cancer Diagnosis and Treatment
- Enzyme Production and Characterization
- Urban Agriculture and Sustainability
- Bariatric Surgery and Outcomes
- Ion Transport and Channel Regulation
- Vascular Procedures and Complications
- Pesticide Exposure and Toxicity
- MicroRNA in disease regulation
- Heat shock proteins research
- Rangeland and Wildlife Management
- Crop Yield and Soil Fertility
Kathmandu University
2018-2025
Nestlé (India)
2023-2024
Southern Illinois University Carbondale
2022-2023
B.P. Koirala Institute of Health Sciences
2020-2021
Dhulikhel Hospital
2020
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2016-2019
Wenzhou Medical University
2016-2019
Agriculture and Forestry University
2019
Government of Sikkim
2000-2006
Bhaati jaanr is an inexpensive high calorie mild-alcoholic beverage prepared from steamed glutinous rice, consumed as a staple food in the Eastern Himalayan regions of Nepal, India and Bhutan. In this paper, fermentation dynamics including growth kinetics physico-chemical changes during bhaati were studied. The population filamentous moulds declined significantly (P < 0.05) each day finally disappeared after 5th day. load yeasts increased 105 cfu/g to 108 cfu g−1 within two days. Lactic acid...
Abstract The aggressive immunological activity elicited by acute viral myocarditis contributes to a large amount of cardiomyocytes loss and poor prognosis patients in clinic. Low‐intensity pulsed ultrasound ( LIPUS ), which is an effective treatment modality for osteoarthropathy, has been recently illustrated regulating the overactive inflammatory response various diseases. Here, we aimed investigate whether could attenuate coxsackievirus B3 CVB 3) infection‐induced injury coordinating...
Background: The fixed drug combination (FDC) of glimepiride and metformin effectively controls blood glucose improves glycated hemoglobin (HbA1c). This study aimed to evaluate the effectiveness safety FDC in managing type-2 diabetes mellitus (T2DM). Materials Methods: retrospective, non-comparative, multi-center cross-sectional was conducted at tertiary care centers Nepal. Adult patients (aged 18 years or older) with T2DM were included. Primary outcomes included changes HbA1c, fasting plasma...
Background: Laboratory testing plays a critical role in healthcare decision-making; however, concerns regarding overutilization and inappropriate persist. Minimum retesting intervals serve as tool to optimize practices resource allocation. This study aimed assess adherence minimum interval guidelines estimate associated costs for commonly prescribed tests, namely HbA1c, 25 hydroxyvitamin D (Vitamin D), thyrotropin, university hospital setting Nepal. Methods: observational utilized secondary...
Abstract This paper is the first report on microbial population and predominant lactic acid bacteria (LAB) of two soft‐varieties (mild strong flavoured) chhurpi., a traditional cheese product Sikkim Himalayas. The enzymatic profiles percentage hydrophobicity (as one criterion potential adhesion capability) LAB were also studied. LAB, yeasts viable mesophilic numbers ranged from 7.6–7.9, 7.0–7.4 7.7–8.0 log10 cfu/g respectively. identified as Lactobacillus plantarum, Lb. curvatus, fermentum,...
Gastric carcinoma is one of the most lethal malignancy at present with leading cause cancer-related deaths worldwide. Aquaporins (AQPs) are a family small, integral membrane proteins, which have been evidenced to play crucial role in cell migration and proliferation different cancer cells including gastric cancers. However, aberrant expression specific AQPs its correlation detect predictive prognostic significance remains elusive. In study, we comprehensively explored immunohistochemistry...
Patients with frequent premature ventricular contractions (PVCs) are often symptomatic. Catheter ablation was usually indicated to eliminate symptoms in patients PVCs-induced cardiomyopathy. Currently, PVCs-ablation is also applied for PVCs and no structural heart diseases (SHD); however, the safety efficacy of these remains unclear. In this retrospective study, data from who underwent January 2010 December 2016 at our hospital retrieved. Predictors complications acute procedural success...
With the chronic ischemia persisting after acute myocardial infarction, accompanying low-degree inflammation and subsequent fibrosis result in progression of cardiac remodeling heart failure. Recently, Sodium Houttuyfonate (SH), a pure compound extracted from Houttuynia cordata, has been confirmed exerting anti-inflammatory anti-fibrotic effects under diseased situations. Here, we aimed to investigate whether SH could reverse post-myocardial infarction by alleviating fibrosis. Left anterior...
Long-term recurrence (LR) is a tendency that re-occurs within 3 months after catheter ablation for atrial fibrillation (AF). Whether very early (VER) 7 days of post prognostic factor LR or not unclear. For this reason, present study sought to examine the relationship between VER and LR. In prospective analysis 378 consecutive patients underwent an initial paroxysmal persistent AF. The association was analyzed by univariate multivariate Cox regression, as well time-dependent receiver operator...
Abdominal aortic aneurysm (AAA), characterized by macrophage infiltration-mediated inflammation and oxidative stress, is a potentially fatal disease. Astragaloside IV (AS-IV) has been acknowledged to exhibit antioxidant anti-inflammatory properties. This study was designed investigate the protective effect of AS-IV against AAA formation induced 3,4-benzopyrene (Bap) angiotensin II (Ang II), explore probable mechanisms. Results showed that decreased formation, reduced infiltration expression...
Urban green space, comprising parks, fields, woodlands, and other semi-natural areas, is a fundamental component of urban ecosystems. The determination the relationship between space sprawl necessary to understand urbanization provision ecosystem services. It has been hypothesized that center (i.e., population economic) areas in fast-growing cities would migrate toward over time. To test this hypothesis, expansion were examined five China U.S. experiencing high rates growth. Landsat images...
We analyzed the relationship of -794 CATT5-8 MIF polymorphisms with soluble in Coronary Atherosclerotic Disease (CAD) patients.A total 256 patients selected, on which 186 normal-coronary and 70 artery disease subjects, were recruited study (Retrospectively registered). Genotyping performed by PCR DNA sequencing. Serum levels measured using an ELISA kit. Patients classified coronary angiogram, CAD based Gensini's integral degree (angiographic scoring system).The allele frequency genotype did...
With the acceleration of urbanization, disturbance to urban landscape patterns causes changes surface runoff and increases risk waterlogging. We studied response relationship between pattern change in Chang–Zhu–Tan metropolitan area for period from 2000 2020, analyzing driving factors that affected runoff. The influence evolution on was using SCS-CN flow generation model, moving window method, Pearson’s analysis. analysis showed forest decreased, while impermeable land increased...
Background: Organ phosphorus compounds are one of the most common causes insecticide poisoning worldwide leading to high degree morbidity and mortality especially in developing countries like Nepal. The liver is main organ that metabolizes various including toxins, chemicals drugs eventually excretes from body. Few studies have been done Nepal see level enzymes among poisoning. This may helps early diagnosis acute hepatic failure reduces OP related death.
 Materials Methods:...
Rice (Oryza sativa L.) is first staple crop of Nepal. The national average yield rice less than its potential yield, for which poor agronomic management has been reported as the critical factor. Among various agro-management practices seedling age, seeding density and nitrogen rates significantly affect growth rice. lower produces taller plant, more effective tiller, sterility higher grain yield. On other hand, older age from gives lowest Transplanting younger with low application...