- Facial Nerve Paralysis Treatment and Research
- Trigeminal Neuralgia and Treatments
- Ear Surgery and Otitis Media
- Voice and Speech Disorders
- Botulinum Toxin and Related Neurological Disorders
- Facial Rejuvenation and Surgery Techniques
- Dysphagia Assessment and Management
- Salivary Gland Tumors Diagnosis and Treatment
- Vestibular and auditory disorders
- Meningioma and schwannoma management
- Reconstructive Facial Surgery Techniques
- Tracheal and airway disorders
- Orthopedic Surgery and Rehabilitation
- Nerve Injury and Rehabilitation
- Hearing Loss and Rehabilitation
- Ophthalmology and Eye Disorders
- Airway Management and Intubation Techniques
- Anesthesia and Pain Management
- Sinusitis and nasal conditions
- Body Image and Dysmorphia Studies
- Peripheral Nerve Disorders
- Temporomandibular Joint Disorders
- Respiratory and Cough-Related Research
- Nausea and vomiting management
- Peripheral Neuropathies and Disorders
Jena University Hospital
2016-2025
Friedrich Schiller University Jena
2010-2024
Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde
2010-2024
Medical University of Vienna
2022
Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde
2011-2022
Poliklinik für Präventive Zahnheilkunde und Kinderzahnheilkunde
2022
Swiss Paraplegic Center
2022
Tirol Kliniken
2022
MED-EL (Austria)
2020-2022
Innsbruck Medical University
2022
Abstract Purpose Facial nerve electrodiagnostics is a well-established and important tool for decision making in patients with facial diseases. Nevertheless, many otorhinolaryngologist—head neck surgeons do not routinely use electrodiagnostics. This may be due to current lack of agreement on methodology, interpretation, validity, clinical application. Electrophysiological analyses the mimic muscles can assist diagnosis, assess lesion severity, aid making. With acute palsy, it valuable...
Abstract Background Reconstructive surgery of the facial nerve is not daily routine for most head and neck surgeons. The published experience on strategies to ensure optimal functional results patients are based small case series with a large variety surgical techniques. On this background it worthwhile develop standardized approach diagnosis treatment asking rehabilitation. Conclusion A feasible: Patients chronic palsy first need an exact classification palsy's aetiology. step-by-step...
Abstract Objectives/Hypothesis: To analyze the benefit of electromyographic (EMG) neuromonitoring during primary surgery on benign parotid lesions for postoperative facial function compared to visual observation only. Study Design: Prospective controlled clinical two‐center trial. Methods: Using an operation microscope, 100 parotidectomies in 96 patients were performed: 50 procedures with a continuous EMG monitoring plus (EMG group), and only control (control group). The rate weakness was...
Abstract A number of neuropathological studies have demonstrated that the olfactory system is among first brain regions affected in Parkinson's disease (PD). These findings correlate with pathophysiological and pathological data show a loss bulb (OB) volume patients PD. However, to date, MRI has not been reliable method for vivo detection this volumetric Using 3.0‐Tesla constructive interference steady‐state sequence, OB was evaluated PD (n = 16) healthy control subjects 16). significant...
Purpose: PSMA-targeted radioligand therapy (PRLT) is a promising treatment option for patients with metastatic castration-resistant prostate cancer (mCRPC). However, high uptake of the radiopharmaceutical in salivary glands (SG) can lead to xerostomia and becomes dose-limiting 225Ac-PSMA-617. This study investigated sialotoxicity 177Lu-PSMA-I&T/-617 monotherapy co-administered 225Ac-PSMA-617 177Lu-PSMA-617 (Tandem-PPRLT). Methods: Three patient cohorts, that had undergone or Tandem-PRLT,...
Owing to a lack of prospective studies, our aim was evaluate diagnostic factors, in particular, motor and non-motor function tests, for prognostication recovery time patients with acute facial palsy (AFP).Prospective cohort study.University hospital.259 AFP.Clinical data, grading, electrophysiological tests other were assessed their contribution time.The predominant origin AFP idiopathic (59%) traumatic (21%). At baseline, the House-Brackmann scale (HB) >III 46% patients. Follow-up 5.6±9.8...
Abstract Objectives There is a lack of data on patients' and diagnostic factors for prognostication complete recovery in patients with Bell's palsy. Design setting Cohort register‐based study 368 palsy uniform diagnostics standardised treatment university hospital from 2007 to 2017 (49% female, median age: 51 years). Main outcome measures Clinical data, facial grading, electrodiagnostics, motor function tests, non‐motor tests onset prednisolone therapy were assessed their impact the...
To determine treatment and outcome in a tertiary multidisciplinary facial nerve center, retrospective observational study was performed of all patients referred between 2007 2018. Facial grading with the Stennert index, Clinimetric Evaluation (FaCE) scale, Disability Index (FDI) were used for evaluation; 1220 (58.4% female, median age: 50 years; chronic palsy: 42.8%) included. Patients acute palsy treated center 3.6 months 10.8 months, respectively. Dominant phase glucocorticoids ± acyclovir...
Biofeedback rehabilitation for facial palsy is not yet routinely available patients. Methods: To improve evidence, the effect of an intensive two-week training combining electromyography (EMG) and visual biofeedback 30 patients (76.7% female; median age: 48.6 years) with post-paralytic synkinesis was objectively evaluated. At beginning each day, EMG amplitudes both halves face were recorded during relaxation using system that synchronously used training. A single-factor analysis variance...
Medium-sized scientific conferences held in hotels large enough to accommodate all participants increase opportunities for constructive discussion during breaks, and evenings that bring together young senior experts of basic sciences clinical specialties. Time group discussions offer new collaborations jobs researchers. Since 1991 the Padova Muscle Days have offered collaborative matured into innovative multidisciplinary results point it came naturally us underline with a neologism now...
Purpose: Bell's palsy, a unilateral, idiopathic facial nerve is common disorder that generally followed by good recovery of function. The aim this study was to investigate the impact such transiently decreased motor control (wit
Ultrasonography can detect structural muscle changes caused by neuromuscular disease, but it has not yet been applied to facial nerve diseases. Quantitative analysis would be the preferred method determine whether ultrasound findings are within normal limits, there no normative data for mimic muscles. The purpose of this study was provide gender-specific ultrasonography area, diameter, and contractility masticatory muscles in adults.Bilateral scans multiple were performed at rest during...
Objective To determine the intrarater, interrater, and retest reliability of facial nerve grading patients with palsy (FP) using standardized videos recorded synchronously during a self‐explanatory patient video tutorial. Study Design Prospective, observational study. Methods The automated from 10 varying degrees FP (5 acute, 5 chronic FP) without tutorial eight (all were rated by five novices experts according to House‐Brackmann system (HB), Sunnybrook Grading System (SB), Facial Nerve 2.0...
In this study we introduce quantitative facial muscle ultrasound as a diagnostic tool for patients with chronic unilateral palsy.Muscle area, thickness, and echo intensity of 6 muscles (frontalis, orbicularis oculi, oris, depressor anguli labii inferioris, mentalis) 2 chewing (temporalis masseter, controls) were measured in 20 palsy.Aside from 1, all significantly smaller on the paralyzed side. With exception frontalis oculi muscles, other showed higher affected Muscle size no side-to-side...
Cerebral plasticity includes the adaptation of anatomical and functional connections between parts involved brain network.However, little is known about network dynamics these connectivity changes.This study investigates impact a pure deefferentation, without deafferentation or damage, on brain.To investigate this issue, MRI was performed 31 patients in acute state Bell3s palsy (idiopathic peripheral facial nerve palsy).All motor paradigm to identify seed regions control.The resting within...
Objectives/Hypothesis To describe changes of motor and nonmotor disabilities in patient with peripheral facial palsy (FP) during treatment using the patient-reported outcome measures (PROMs) Facial Clinimetric Evaluation (FaCE), Disability Index (FDI), Short Form 36-Item Questionnaire (SF-36) to analyze predictors for these Study Design Prospective, single-center longitudinal study. Methods One hundred twenty patients FP underwent at least two PROMs between 2012 2015. Predictors were...
Does electrical stimulation (ES) of denervated muscles delay or prevent reinnervation, increase synkinesis? In this retrospective study we evaluate the outcome, with and without ES, patients acutely facial muscles.The effect ES was analyzed in two experiments. first experiment, 39 (6 home-based median 17.5 months) underwent nerve reconstruction surgery. Time to recovery volitional movements analyzed. The second experiment involved 13 (7 19 during spontaneous reinnervation. Sunnybrook eFACE...
Introduction: There is no standardized method for examination of facial muscles with ultrasound. The purpose this study was to identify those accessible reliable identification and provide reference data. Methods: In healthy subjects all were screened visibility, separation from adjacent muscles, reliability landmarks. Bilateral scans performed in 40 adult volunteers. Results: Six clearly demarcated These were: frontalis, orbicularis oculi, oris, depressor anguli labii inferioris, mentalis...