A5031255463- Seaweed-derived Bioactive Compounds
- Fatty Acid Research and Health
- Adipokines, Inflammation, and Metabolic Diseases
- Immune Response and Inflammation
- Gut microbiota and health
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Helicobacter pylori-related gastroenterology studies
- 3D Printing in Biomedical Research
- Marine and coastal ecosystems
- Innovative Microfluidic and Catalytic Techniques Innovation
- Algal biology and biofuel production
- Herbal Medicine Research Studies
- Platelet Disorders and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Hydrogels: synthesis, properties, applications
- Adipose Tissue and Metabolism
- Blood Coagulation and Thrombosis Mechanisms
- Diet and metabolism studies
- bioluminescence and chemiluminescence research
- Pharmacological Effects of Natural Compounds
- Medicinal Plants and Bioactive Compounds
- Public Health and Nutrition
- Proteoglycans and glycosaminoglycans research
- Influenza Virus Research Studies
- Apelin-related biomedical research
Nippon Chemical Industrial (Japan)
2018-2024
Suzuka University of Medical Science
2022-2023
Mie University
2021
Screen
2021
Influenza viruses cause a significant public health burden each year despite the availability of anti-influenza drugs and vaccines. Therefore, new virus agents are needed. Rhamnan sulfate (RS) is sulfated polysaccharide derived from green alga Monostroma nitidum. Here, we aimed to demonstrate antiviral activity RS, especially against influenza A (IFV) infection, in vitro vivo. RS showed inhibitory effects on viral proliferation enveloped vitro. Evaluation anti-IFV that it inhibited both...
Rhamnan sulfate (RS), extracted from the seaweed Monostroma nitidum, suppresses vascular endothelial inflammation and arteriosclerosis, decreases blood glucose levels, improves lipid metabolism intestinal environment. We investigated whether RS diabetic brain dysfunction using a hyperglycemic mouse model induced by pretreatment with nicotinamide streptozotocin followed oral administration of high-fat diet maltodextrin (MD) for 4 months. was administered in 1% MD solution at doses 100, 300,...
(1) Background: The red seaweed Palmaria mollis (PM), which has a bacon-like taste, is increasingly being included in Western diets. In this study, we evaluate anti-obesity effects of PM using diet-induced obese (DIO) zebrafish and mice models. (2) Methods: We fed PM-containing feed to DIO-zebrafish mice, evaluated the also analyzed gene expression changes their liver visceral adipose tissues (VAT). (3) Results: ameliorated several traits both animals, including dyslipidaemia, hepatic...
Abstract Rhamnan sulphate (RS), a sulphated polysaccharide from Monostroma nitidum , possesses several biological properties that help in treating diseases such as viral infection, thrombosis, and obesity. In the present study, we first administered RS (0.25 mg/g food volume) orally to high-fat diet-treated mice for 4 weeks. increased faecal volume calorie excretion with decreased plasma lipids, which was accordance results of our previous zebrafish study. Notably, amount by mice,...
Abstract Rhamnan sulphate (RS) is a sulphated polysaccharide found in green algae such as Monostroma nitidum that exhibits various biological functions, including anticoagulant, antitumour, antiviral, and anti‐obesity properties. In our previous clinical trial, we demonstrated RS intake improves constipation. However, no specific bacteria showed significant ( p < .05) change. Notably, these results were obtained after short inoculation period of only 2 weeks. the present study, to...
We previously reported that rhamnan sulfate (RS) purified from Monostroma nitidum significantly suppressed lipopolysaccharide (LPS)-induced inflammation in cultured human vascular endothelial cells. Here, we analyzed the effect of orally administered RS on LPS-induced damage to mouse organs and endothelium. (1 mg) was daily BALB/c mice, 50 μg LPS intraperitoneally day 8, Evans blue injected into tail vein 6 h later. After 30 min, LPS-treated mice showed pulmonary leakage elevated plasma...
Oral administration of rhamnan sulfate (RS), derived from the seaweed Monostroma nitidum, markedly suppresses inflammatory damage in vascular endothelium and organs lipopolysaccharide-treated mice. This study aimed to analyze whether orally administered RS inhibits development atherosclerosis, a chronic inflammation arteries. ApoE-deficient female mice were fed normal or high-fat diet (HFD) with without for 12 weeks. Immunohistochemical mRNA analyses atherosclerosis-related genes performed....
Rhamnan sulfate (RS) is a sulfated polysaccharide extracted from the cell wall of green alga
Background: The red seaweed Palmaria mollis (PM) has recently become popular as foodstuffs due to their relatively high proteins, in addition potential a source of biofunctional molecules and antioxidant ingredients. We previously performed small-scale screening with diet-induced obese (DIO) zebrafish, found that PM is one strong candidates for the treatment obesity its-related diseases.
Not Published