Toshio Kawahara

ORCID: 0000-0003-0168-5825
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About
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Research Areas
  • Superconducting Materials and Applications
  • Physics of Superconductivity and Magnetism
  • HVDC Systems and Fault Protection
  • Carbon Nanotubes in Composites
  • Influenza Virus Research Studies
  • Advanced biosensing and bioanalysis techniques
  • Graphene research and applications
  • SARS-CoV-2 detection and testing
  • Advanced Thermoelectric Materials and Devices
  • Diamond and Carbon-based Materials Research
  • stochastic dynamics and bifurcation
  • Glycosylation and Glycoproteins Research
  • Virus-based gene therapy research
  • Thermal properties of materials
  • Viral gastroenteritis research and epidemiology
  • Biosensors and Analytical Detection
  • Advanced Biosensing Techniques and Applications
  • Advancements in Semiconductor Devices and Circuit Design
  • Superconductivity in MgB2 and Alloys
  • Probiotics and Fermented Foods
  • Spacecraft and Cryogenic Technologies
  • Mechanical and Optical Resonators
  • Particle accelerators and beam dynamics
  • Immune Response and Inflammation
  • Diabetes and associated disorders

Chubu University
2014-2023

Kasugai Municipal Hospital
2017

Tokyo University of Marine Science and Technology
2014

Influenza viruses cause a significant public health burden each year despite the availability of anti-influenza drugs and vaccines. Therefore, new virus agents are needed. Rhamnan sulfate (RS) is sulfated polysaccharide derived from green alga Monostroma nitidum. Here, we aimed to demonstrate antiviral activity RS, especially against influenza A (IFV) infection, in vitro vivo. RS showed inhibitory effects on viral proliferation enveloped vitro. Evaluation anti-IFV that it inhibited both...

10.3390/md18050254 article EN cc-by Marine Drugs 2020-05-13

There are global concerns about threat of pandemic caused by the human-infectious avian influenza virus. To prevent oncoming pandemic, it is crucial to analyze viral affinity human-type or avian-type sialoglycans with high sensitivity at speed. Graphene-FET (G-FET) realizes such high-sensitive electrical detection targets, owing graphene's carrier mobility. In present study, G-FET was functionalized using and employed for selective lectins from Sambucus sieboldiana Maackia amurensis as...

10.7567/jjap.56.030302 article EN Japanese Journal of Applied Physics 2017-02-07

A monogalactosyl diacylglyceride (MGDG) was isolated as an antiviral component from Coccomyxa sp. KJ (IPOD FERM BP-22254) via bioassay-guided fractionation. α-Linolenic acid (C18:3) and 7,10,13-hexadecatrienoic (C16:3) accounted for approximately 72% 23%, respectively, of the MGDG total fatty acids MGDG. The showed virucidal activity against herpes simplex virus type 2 (HSV-2), a pathogen that causes genital herpes. Physical changes in HSV-2 shape were observed after treatment with MGDG,...

10.1371/journal.pone.0219305 article EN cc-by PLoS ONE 2019-07-16

The rapidly evolvable influenza A virus has caused pandemics linked to millions of deaths in the past century. Influenza viruses are categorized by H (hemagglutinin; HA ) and N (neuraminidase; NA) proteins expressed on viral envelope surface. Analyses suggest that gene segment comes from a nonhuman virus, which is then introduced into an immunologically naïve human population with potentially devastating consequences. As prerequisite for infection, molecules H1–H16 must be able bind specific...

10.1111/febs.14431 article EN FEBS Journal 2018-03-15

Here, we report on the large-area synthesis of hBN layer at a comparatively lower temperature using ammonia borane as precursor by microwave assisted surface wave plasma (MW-SWP) chemical vapour deposition (CVD). The solid was sublimed inside CVD chamber and decomposed to form radicals, which allowed growth (∼500 °C). Cu catalyst Si wafer confirmed X-ray photoelectron spectroscopy, ultraviolet absorption Fourier-transform infrared spectroscopy transmission electron microscopy analysis. film...

10.1063/1.5091529 article EN cc-by AIP Advances 2019-03-01

We constructed a test stand of 20 m-class DC superconducting power transmission cable in Chubu University, 2006. The consisted thirty-nine Bi-2223 HTS tapes two layers; nineteen were used the first layer and twenty second layer. One features is that each tape electrically isolated. Therefore, we can apply current to individual measured critical one when was applied other tapes, compared result with magnetic field calculation due current. increased by 2 ~ 4% all eighteen same From...

10.1109/tasc.2010.2089964 article EN IEEE Transactions on Applied Superconductivity 2010-12-10

We constructed a facility of 200-m HTS power transmission test cable (CASER-II) in 2010. Generally, an contracts about 0.3% when it is cooled from room temperature to liquid nitrogen (LN2) temperature. The contraction the corresponds 0.6 m. In order realize system, essential issue absorb mechanical stress during cycles cooling-down and heating-up. CASER-II uses smooth pipes as cryogenic pipe for line reduce pressure drop flow, whereas other cables use corrugated stress. employed (1) movable...

10.1109/tasc.2012.2235510 article EN IEEE Transactions on Applied Superconductivity 2012-12-20

Background.The Coccomyxa sp.strain KJ (Coccomyxa KJ), a microalga found in Japan, has potential function controlling viral infections.Recently, its dry powder been marketed as health food product.Objectives.This pilot study investigated the effects of tablet intake on allergic reactions and immune functions healthy participants. Materials methods.Nine volunteers (4 males 5 females) who expressed interest foods containing KJ, were willing to undergo blood tests, recruited.Each individual was...

10.17219/acem/166665 article EN cc-by Advances in Clinical and Experimental Medicine 2023-06-30

Carbon nanotubes (CNTs) are one of the candidates for nanosize devices such as field-effect transistors. CNT transistors (CNTFETs) have very special properties sometimes caused by surface states. For example, they also well known noisy molecule adhesion on surface. Nonlinear systems, however, some advantages weak signal detection or enhancement in working with noise. The small was conventionally studied stochastic resonance. Therefore, we study modification nonlinearity systems under actual...

10.1143/jjap.49.02bd11 article EN Japanese Journal of Applied Physics 2010-02-01

Abstract Sialic acids are unique sugars with negative charge and exert various biological functions such as regulation of immune systems, maintenance nerve tissues expression malignant properties cancers. Alpha 2,6 sialylated N-glycans, one representative sialylation forms, synthesized by St6gal1 or St6gal2 gene products in humans mice. Previously, it has been reported that is ubiquitously expressed almost all tissues. On the other hand, mainly embryonic perinatal stages brain However, roles...

10.1093/glycob/cwaa105 article EN Glycobiology 2020-11-25

In this study, we created nonplanar structures of inorganic optical materials by femtosecond (fs) laser lithography-assisted micromachining, which is a combined process nonlinear lithography and plasma etching. Three-dimensional patterns, formed inside positive-tone resist fs exposure, were transferred to the underlying substrates This enables fabrication Si lines with constant width 5 µm, even on 65-µm-high step. We demonstrated SiO2-based micro-Fresnel zone plates convex lenses....

10.1143/apex.1.127001 article EN Applied Physics Express 2008-12-05

For superconducting direct current applications, heat leak reduction at the terminal is a key issue for high performance systems and especially small ones such as distribution in internet data centers. We propose double Peltier lead (PCL), where suitable combination of two modules can enhance PCL. Using model parameters actual thermoelectric materials, we estimated on PCL using thermal balance equation. At PCL, large temperature difference be split to materials then enhanced. As each has...

10.1109/tasc.2010.2096451 article EN IEEE Transactions on Applied Superconductivity 2011-01-07

In accordance with the conventional design of superconducting power transmission (SC PT) line, HTS cable should be placed into a carefully heat-insulated cryopipe filled cryogen (usually liquid nitrogen, LN2) in order to maintain its temperature low. Circulating LN2 removes heat penetrating through insulation layers. The circulation rate depends on load and length line. Since working range is restricted, it easy show that pressure drop, Δp, increases dramatically being almost cubic function...

10.1016/j.phpro.2012.06.307 article EN Physics Procedia 2012-01-01

Heat leak from the current lead is major source of power loss for superconducting (SC) magnets, motors and generators, short distance SC transmission lines. Therefore, reducing heat can improve economy system allow use systems commercially. The Peltier was proposed developed at Chubu University to reduce electrical consumption refrigerator. leakage saves almost 40%, but requirement refrigerator still high. In order realize greater savings, multistage (MCL) gas-cooled MCL are proposed....

10.1109/tasc.2013.2243896 article EN IEEE Transactions on Applied Superconductivity 2013-01-29

The reduction of the heat leak from terminal is one important issues to realize applications superconductivity, and Peltier current lead (PCL) has been developed until now. PCL as compared with usual copper almost 40%, however still required improve total efficiency superconducting system. Therefore, we estimate performance multi-stage (MCL) propose a gas-cooled MCL in this paper. principle depends on that COP refrigerator higher high temperature, resistivity lower at temperature. But was...

10.1016/j.phpro.2012.03.508 article EN Physics Procedia 2012-01-01

Bacterial RNA has recently emerged as an immune-stimulating factor during viral infection. The immune response in organism is directly related to the progression of virus infections. Lactic acid bacteria particular have anticancer, bioprotective, and antiallergic effects by modulating immunity. Here, we aimed demonstrate effect bacterial on vitro production IL-12, a proinflammatory cytokine, vivo activity against influenza A (IFV) Oral administration heat-killed Enterococcus faecalis KH2...

10.12938/bmfh.2020-019 article EN Bioscience of Microbiota Food and Health 2020-09-11
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