Liangwan Chen

ORCID: 0000-0003-1269-4057
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About
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Research Areas
  • Aortic Disease and Treatment Approaches
  • Mechanical Circulatory Support Devices
  • Congenital Heart Disease Studies
  • Cardiac Valve Diseases and Treatments
  • Aortic aneurysm repair treatments
  • Pulmonary Hypertension Research and Treatments
  • Intensive Care Unit Cognitive Disorders
  • Respiratory Support and Mechanisms
  • Cardiac Structural Anomalies and Repair
  • Infectious Aortic and Vascular Conditions
  • Cardiovascular Function and Risk Factors
  • Family and Patient Care in Intensive Care Units
  • Acute Kidney Injury Research
  • Chronic Kidney Disease and Diabetes
  • Hip and Femur Fractures
  • Cardiac and Coronary Surgery Techniques
  • Sexual function and dysfunction studies
  • Cardiac Arrest and Resuscitation
  • Apelin-related biomedical research
  • Hormonal Regulation and Hypertension
  • Congenital heart defects research
  • Cardiovascular Issues in Pregnancy
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Metalloenzymes and iron-sulfur proteins
  • Cardiac, Anesthesia and Surgical Outcomes

Fujian Medical University
2015-2025

Union Hospital
2015-2025

Full median sternotomy is the traditional approach for treatment of left ventricular aneurysms (LVA) with or without concomitant septal rupture (VSR). However, it has some disadvantages such as reduced breathing and exercise thoracic stability, which may increase surgical risk older fragile patients. Herein, we report a case successful minimally invasive bilateral thoracotomy. A 79-year-old male patient visited our center complaining breathlessness orthopnea 21 days after an acute myocardial...

10.1186/s13019-025-03355-4 article EN cc-by-nc-nd Journal of Cardiothoracic Surgery 2025-02-24

Objective: The link between bovine aortic arch (BAA) and stroke after thoracic endovascular repair (TEVAR) was investigated. Methods: multicenter retrospective study included consecutive Stanford type B dissection patients undergoing TEVAR from January 2019 to December 2023. A multivariable logistic regression utilized assess the correlation BAA early stroke, while a Cox employed evaluate association overall stroke. Kaplan-Meier curves were used compare freedom rates. Results: In total, 138...

10.1177/15266028251321284 article EN Journal of Endovascular Therapy 2025-03-13

Abstract Background Blood glucose variability is associated with poor prognosis after cardiac surgery, but the relationship between and postoperative delirium in patients acute aortic dissection unclear. The study aims to investigate association of blood patients. Methods We prospectively analyzed 257 including 103 delirium. were divided into two groups according whether was present. outcome measures delirium, length Intensive Care Unit stay, duration hospital stay. Multivariable Cox...

10.1186/s13019-021-01456-4 article EN cc-by Journal of Cardiothoracic Surgery 2021-04-15

The decrease in sleep quality leads to an increased risk of cardiovascular disease and is closely related the prognosis various diseases. However, relationship between preoperative postoperative clinical outcomes patients with acute aortic dissection still unclear. We aimed assess dissection. assessed participants' dissection, which included prolonged mechanical ventilation, delirium, in-hospital death, continuous renal replacement therapy, intensive care unit stay time, length stay....

10.1111/jsr.14411 article EN cc-by-nc-nd Journal of Sleep Research 2024-11-20

<title>Abstract</title> Full median sternotomy is the traditional approach for treatment of left ventricular aneurysms (LVA) with or without concomitant septal rupture (VSR). However, it has some disadvantages such as reduced breathing and exercise thoracic stability, which may increase surgical risk older fragile patients. Herein, we report a case successful minimally invasive bilateral thoracotomy. <bold>Patient method</bold> A 79-year-old male patient visited our center complaining...

10.21203/rs.3.rs-4904148/v1 preprint EN Research Square (Research Square) 2024-09-12

Objective: This study aims to investigate the association between preoperative serum uric acid high-density lipoprotein cholesterol ratio (UHR) and occurrence of postoperative acute kidney injury (AKI) in patients who underwent coronary artery bypass grafting (CABG). Methods: A prospective observational was conducted at Fujian Heart Medical Center May 2022 December 2023, recruiting scheduled for CABG. Participants were categorized into two groups based on AKI post-surgery. Univariate...

10.2147/ijgm.s482440 article EN cc-by-nc International Journal of General Medicine 2024-12-01

Abstract Background: To compare postoperative sexual dysfunction (SD) and quality of life (QOL) in Type A Aortic Dissection (AAD) Patients Different Ages. Methods : From January 2018 to December 2019, 204 AAD survivors Union Hospital Fujian Medical University were selected divided into youth group (less than 50 years old) elderly (more old). We evaluated SD according the male International Erectile Dysfunction Index (IIEF-5) female function index (FSFI) . The Short Form 12 Health Survey...

10.21203/rs.3.rs-56025/v1 preprint EN cc-by Research Square (Research Square) 2020-08-17

Background: The hydration state of the body is getting more and attention from researchers. purpose this study to investigate relationship between impaired status postoperative hospitalization death in patients with A AAD. Methods: From January 2019 October 2021, clinical data 299 undergoing AAD surgery were retrospectively analyzed. Patients divided into normal group, imminent dehydration group current according standard at admission. Univariate multivariate logistic regression analysis...

10.2147/ijgm.s426612 article EN cc-by-nc International Journal of General Medicine 2023-09-01

Objective. To establish risk factors for predicting preoperative ruptures in patients with acute type A aortic dissection (ATAAD) based on computed tomography angiography (CTA) imaging features alone. Methods. We retrospectively reviewed ATAAD treated between January 2017 and December 2021 Fujian Medical University Union Hospital, China. The primary outcome was rupture after admission. Multivariate logistic regression analysis performed basic characteristics CTA variables selected by the...

10.1155/2023/1337373 article EN Journal of Cardiac Surgery 2023-10-09

Objective To modify the model of right ventricular outflow tract obstruction (RVOTO) in rats, and to search for optimal method establishment. Methods Thirty male SD rats were randomly divided three groups: RVOTO group, sham group control group. There 10 each The animals given pulmonary arterial constriction (PAC), those thoracotomy without PAC, no surgical operation. heart specimens harvested after 4 weeks. thickness ventricle, hyperplastic state myocardiac cells fiber volume ratio...

10.3760/cma.j.issn.1001-9030.2018.02.051 article EN Zhonghua shiyan waike zazhi 2018-02-08

Background: Aortic dissection (AD) is a cardiovascular disease that most often fatal. In this study, the differences in exosomes between patients with AD and healthy individuals were analyzed to explore pathogenesis of AD.Methods: RNA sequencing mass spectrometry performed differentially expressed miRNAs, mRNAs, proteins among derived from plasma aortic people. Through series bioinformatics analyses, immunofluorescence, fluorescence situ hybridization, we targeted key pathogenic factors,...

10.2139/ssrn.4314011 article EN SSRN Electronic Journal 2022-01-01

Abstract Background: Prolonged mechanical ventilation (PMV) among acute type A aortic dissection (AAAD) may affect the prognosis, but poorly known about direct economic burden of PMV in patients with AAAD. The present study was contributing to filling this knowledge gap. Methods: This a retrospective cohort study. Age, gender, payment methods, and postoperative complications were matched at 1:1 ratio by using propensity score analysis AAAD patients. expressed as median differences various...

10.21203/rs.3.rs-754251/v1 preprint EN cc-by Research Square (Research Square) 2021-08-02
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