A5041111086- Probiotics and Fermented Foods
- Gut microbiota and health
- Piezoelectric Actuators and Control
- Salmonella and Campylobacter epidemiology
- Bacteriophages and microbial interactions
- Iterative Learning Control Systems
- Clostridium difficile and Clostridium perfringens research
- Robotic Mechanisms and Dynamics
- Viral gastroenteritis research and epidemiology
- Advanced Measurement and Metrology Techniques
- Aeroelasticity and Vibration Control
- Escherichia coli research studies
- Bacillus and Francisella bacterial research
- Antibiotic Resistance in Bacteria
- Cancer Research and Treatments
- Geophysics and Sensor Technology
- Reproductive System and Pregnancy
- Animal Behavior and Welfare Studies
- Antimicrobial Peptides and Activities
- Advanced MEMS and NEMS Technologies
- Toxin Mechanisms and Immunotoxins
- Antimicrobial Resistance in Staphylococcus
- Ruminant Nutrition and Digestive Physiology
- Shape Memory Alloy Transformations
- Advanced Algorithms and Applications
Huazhong Agricultural University
2022-2025
Center of Hubei Cooperative Innovation for Emissions Trading System
2022-2025
Nanjing University of Aeronautics and Astronautics
2022-2024
Jiangxi Agricultural University
2018-2024
Nanjing Forestry University
2020-2022
Henan Agricultural University
2017
Henan University
2017
The rapid emergence of phage-resistant bacterial mutants is a major challenge for phage therapy. Phage cocktails have been considered one approach to mitigate this issue. However, the synergistic effect randomly selected phages in ambiguous. Here, we rationally designed cocktail consisting four that utilize lipopolysaccharide (LPS) O antigen, LPS outer core, inner and membrane proteins BtuB TolC on Salmonella enterica serovar Enteritidis cell surface as receptors. We demonstrated four-phage...
The emergence of antibiotic-resistant bacteria has attracted interest in the field endolysins. Here, we analyzed diversity Streptococcus endolysins and identified a new endolysin, Ply2741, that exhibited broad-spectrum bactericidal activity. Our results demonstrated Ply2741 could effectively eradicate multidrug-resistant gram-positive pathogens vitro vivo. Structural analysis revealed activity depends on classic "Cys-His-Asn" catalytic triad. Site-directed mutagenesis further conserved...
Abstract Multi-degree-of-freedom (DOF) precision positioning stages (PPS) based on displacement amplifiers are commonly designed and used in engineering applications. However, the equivalent load cross-coupling effects these PPS can adversely impact kinematic performance of amplifiers, resulting a significant reduction accuracy. To this end, novel mathematical model has been developed chain-based compliance matrix (CMM) beam constraint model, enabling precise calculation amplification ratio...
Introduction Streptococcus suis , an important zoonotic and opportunistic pathogen in pigs, brings huge economic losses to the pig-raising industry infects humans with diseases. Phage lysin is regarded as a promising substitute for antibiotics due its ability quickly efficiently kill bacteria without easily developing resistance. However, their clinical applications have been hindered by inherent instability under environmental stressors. Methods We constructed B. subtilis spores displaying...
Endometritis is the main cause of decreased reproductive performance sows, while one most important factors in etiology sow endometritis an aberration birth canal microbiota. Therefore, people began to pay attention microbiota structure and composition sows with endometritis. Interestingly, we found that risk was increased constipation clinical practice, which may imply intestinal flora related occurrence understanding relationship between host has become exceptionally crucial. In this...
Abstract Enterotoxigenic E. coli is one of the bacterial pathogens contributing to global resistance crisis in public health and animal husbandry. The problem antibiotic becoming more serious, phage considered potential alternatives antibiotics that could be utilized treat infections. Our study isolated identified a lytic PGX1 against multidrug-resistant enterotoxigenic EC6 strain from sewage. lysis profile revealed exhibited effect on strains serotype O60. Through whole genome sequencing...
This paper presents a novel non-gyro six-axis accelerometer based on derivative of Stewart parallel mechanism (SPM). To reduce the impact interference noise, set geometric constraint equations are presented to compensate errors redundant outputs. A decoupling algorithm is introduced for easy modelling this multiple-axis vibration problem. An auxiliary angular velocity adopted so that system dynamic can be directly solved by traditional explicit recursive formulas (ERFs) real-time...
To better understand the prevalence of Gallibacterium anatis in different poultry species, a rapid and accurate method was developed to detect G. using TaqMan fluorescent quantitative polymerase chain reaction (qPCR). Specific primers probe were designed based on reference gtxA gene sequence. The qPCR standard curve showed good linear relationship, reproducibility, sensitivity, specificity, indicating its suitability for identification analysis. A comparison detection results 160 clinical...
The solution of the dynamic equations six-axis accelerometer is a prerequisite for sensor calibration, structural optimization, and practical application. However, forward (FDEs) inverse (IDEs) this type system have not been completely solved due to strongly nonlinear coupling relationship between inputs outputs. This article presents comprehensive study FDEs IDEs based on parallel mechanism. Firstly, two sets are constructed Newton–Euler method in configuration space. Secondly, analytical...
Although the bacterial composition of boar ejaculate has been extensively studied, extended semen is often overlooked, despite potential risks these microorganisms may pose to long-term preservation at 15-17°C. In this study, we characterized community and discovered that Pseudomonas spp. was dominant flora. The strains were further isolated identified as a new species in fluorescens group named GXZC strain, which had adverse effects on sperm quality better adapted growth 17°C. Antimicrobial...
Purpose This paper aims to improve the kinematic modeling accuracy of a spatial three-degrees-of-freedom compliant micro-motion parallel mechanism by proposing modified method based on structural matrix (SMM). Design/methodology/approach analyzes problem that torsional compliance equation circular notched hinge is no longer applicable because it subject bilateral restrained torsion. The introducing relative length coefficient. input coupling effect, which often neglected, considered in...
Bacillus velezensis is a species of that has been widely investigated because its broad-spectrum antimicrobial activity. However, most studies on B. have focused the biocontrol plant diseases, with few reports antagonizing Salmonella Typhimurium infections. In this investigation, it was discovered HBXN2020, which isolated from healthy black pigs, possessed strong anti-stress and antibacterial Importantly, HBXN2020 did not cause any adverse side effects in mice when administered at various...
Bacillus velezensis is a novel species of that has been widely investigated because its broad-spectrum antimicrobial activity. However, most studies on have focused biocontrol plant diseases, with few reports antagonizing Salmonella Typhimurium infections. In this study, HBXN2020 was isolated from healthy black piglets and found to exhibit antibacterial activity robust anti-stress capabilities. Importantly, did not cause any adverse side effects in mice when administered at various doses (1...
Bacillus velezensis is a species of that has been widely investigated because its broad-spectrum antimicrobial activity. However, most studies on have focused the biocontrol plant diseases, with few reports antagonizing Salmonella Typhimurium infections. In this investigation, it was discovered HBXN2020, which isolated from healthy black pigs, possessed strong anti-stress and antibacterial Importantly, HBXN2020 did not cause any adverse side effects in mice when administered at various doses...
Bacillus velezensis is a species of that has been widely investigated because its broad-spectrum antimicrobial activity. However, most studies on have focused the biocontrol plant diseases, with few reports antagonizing Salmonella Typhimurium infections. In this investigation, it was discovered HBXN2020, which isolated from healthy black pigs, possessed strong anti-stress and antibacterial Importantly, HBXN2020 did not cause any adverse side effects in mice when administered at various doses...