Hongwei Guo

ORCID: 0000-0003-4012-9055
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Research Areas
  • Mycotoxins in Agriculture and Food
  • Veterinary medicine and infectious diseases
  • Coccidia and coccidiosis research
  • Parasitic Infections and Diagnostics
  • Wheat and Barley Genetics and Pathology
  • Robotic Mechanisms and Dynamics
  • interferon and immune responses
  • Animal Nutrition and Physiology
  • Genomics, phytochemicals, and oxidative stress
  • Biofuel production and bioconversion
  • Piezoelectric Actuators and Control
  • Agriculture Sustainability and Environmental Impact
  • Iterative Learning Control Systems
  • Mercury impact and mitigation studies
  • NF-κB Signaling Pathways
  • Plant pathogens and resistance mechanisms
  • Ginger and Zingiberaceae research
  • Food composition and properties
  • Bioeconomy and Sustainability Development
  • Mesenchymal stem cell research
  • Microbial Metabolites in Food Biotechnology
  • Selenium in Biological Systems
  • Histone Deacetylase Inhibitors Research
  • Alzheimer's disease research and treatments
  • Helminth infection and control

Huanghuai University
2022-2024

Harbin Institute of Technology
2021-2024

Henan Agricultural University
2013-2022

Henan University
2017-2020

ORCID
2020

Jinan Military General Hospital
2012-2018

Second Military Medical University
2018

Tibet University
2011

China Agricultural University
2007

Abstract Aflatoxin B 1 (AFB ) is one of the most dangerous mycotoxins for humans and animals. This study aimed to investigate effects compound probiotics (CP), CP supernatant (CPS), AFB -degradation enzyme (ADE) on chicken embryo primary intestinal epithelium, liver kidney cell viabilities, determine functions + ADE (CPADE) or CPS (CPSADE) alleviating cytotoxicity induced by . The results showed that decreased viabilities in dose-dependent time-dependent manners. optimal concentrations...

10.1186/s13568-021-01196-7 article EN cc-by AMB Express 2021-03-01

The aim of this study was to evaluate the effects compound mycotoxin detoxifier (CMD) on alleviating toxic effect aflatoxin B1 (AFB1) for broiler growth performance. One-kilogram CMD consists 667 g B1-degrading enzyme (ADE, 1,467 U/g), 200 montmorillonite and 133 probiotics (CP). feeding experiment divided into 2 stages (1–21 d 22–42 d). In early stage, a total 300 one-day-old Ross broilers were randomly 6 groups, 5 replications each group, 10 (half male half female) in replication. later...

10.1016/j.psj.2022.102434 article EN cc-by-nc-nd Poultry Science 2022-12-21

This study investigated the effects of compound probiotics (CP) on AFB

10.1016/j.ecoenv.2024.116619 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2024-06-25

This study investigated the effects of compound probiotics (CP) as starter cultures to reduce AFB1 residues and improve safety quality chicken jerky. First, Enterococcus faecalis, Candida utilis, Lactobacillus casein, Bacillus subtilis were subjected single strain fermentation experiments. Then, a three-factor, three-level response surface methodology design was used select CP based on degradation histamine content. The optimal included casein at initial viable counts 3.0 × 108, 109 CFU/mL...

10.1016/j.foodcont.2024.110601 article EN cc-by-nc-nd Food Control 2024-05-27

In order to alleviate the toxic effects of aflatoxins B1 (AFB1) on inflammatory responses in intestine, liver, and kidney broilers, aflatoxin B1-degrading enzyme, montmorillonite, compound probiotics were selected combined make a triple-action mycotoxin detoxifier (CMD). The feeding experiment was divided into two stages. early stage (1–21 day), total 200 one-day-old Ross broilers randomly four groups; later (22–42 160 aged at 22 days assigned groups: Group A: basal diet (4.31 μg/kg AFB1);...

10.3390/toxins14100665 article EN cc-by Toxins 2022-09-24

The aim of this study was to evaluate the detoxification aflatoxin B1 (AFB1) in vitro and broiler chickens using a triple-action compound mycotoxin detoxifier (CMD). Response surface methodology (RSM) used AFB1 artificial gastrointestinal fluid (AGIF) vitro. AFB1-degradation rate 41.5% (P < .05) when probiotic (CP) which visible counts Bacillus subtilis, Lactobacillus casein, Enterococcus faecalis Candida utilis were 1.0 × 105, 107 105 CFU/mL, respectively. When CP combined with 0.1%...

10.1080/19440049.2021.1957159 article EN Food Additives & Contaminants Part A 2021-08-09

To better understand the prevalence of Gallibacterium anatis in different poultry species, a rapid and accurate method was developed to detect G. using TaqMan fluorescent quantitative polymerase chain reaction (qPCR). Specific primers probe were designed based on reference gtxA gene sequence. The qPCR standard curve showed good linear relationship, reproducibility, sensitivity, specificity, indicating its suitability for identification analysis. A comparison detection results 160 clinical...

10.1080/03079457.2017.1416590 article EN Avian Pathology 2017-12-15

Eimeria tenella is an obligate intracellular parasite of the chicken cecum; it brings huge economic loss to industry. Enolase a multifunctional glycolytic enzyme involved in many processes parasites, such as infection and migration. In this study, effect diclazuril on expression enolase second-generation merozoites E. (EtENO) was reported. The prokaryotic plasmid pET-28a-EtENO constructed transformed into Escherichia coli BL21 (DE3). Then, subjected under induction...

10.1016/j.psj.2020.09.068 article EN cc-by-nc-nd Poultry Science 2020-10-07

Low molecular mass polypeptides 2 (LMP2) and Multicatalytic endopeptidase complex subunit (MECL-1) are two of three catalytic β-type subunits the 20s proteasome upon interferon gamma-induction. LMP2 is critical for production major histocompatibility (MHC) class I ligand T-lymphocytes. The gene located in MHC region, but MECL-1 outside region. They involved antigen presentation important candidate genes an initial exploration relationships between processing disease resistance. In this...

10.1080/10425170601119222 article EN DNA sequence 2007-01-01

Objective To explore the clinicopathological features and characteristics of gene mutation in patients with Aicardi-Goutieres syndrome(AGS). Methods The clinical image one family AGS were summarized. The cutaneous pathological changes observed by biopsy. TREX1 genes sequenced extracted DNA peripheral blood mononuclear cell. Results The main proband included reoccurred chilblain, encephalopathy, calcifications centrum ovale. biopsies skin demonstrated sporadic inflammatory...

10.3760/cma.j.issn.1006-7876.2014.02.006 article EN Chin J Neurol 2014-02-08

1. Aguilar D.L., Rodriguez-Jasso M., Zanuso E., de Rodriguez D.J., Amaya-Delgado L., Sanchez A., Ruiz HA., 2018. Scale-up and evaluation of hydrothermal pretreatment in isothermal non-isothermal regimen for bioethanol production using agave bagasse. Bioresour. Technol. 263, 112–119, https://doi.org/10.1016/j.bior.... CrossRef Google Scholar

10.22358/jafs/124044/2020 article EN Journal of Animal and Feed Sciences 2020-06-21

In this paper, the statics analysis of heavy-duty transfer robot is first performed to determine maximum stress each link in dangerous position. The minimum mass arm taken as optimization target, and strength conditions deformation are constraint conditions. Using target function ANSYS Workbench, thickness width optimized. And based on optimized structure size, designed. results show that forearm support decreased by 24.66% 28.71% respectively, so lightweight realized.

10.1109/crc52766.2021.9620175 article EN 2021-10-09

Abstract Background: Coccidiosis caused by Eimeria tenella infection, directly or indirectly leads to great loss poultry industry. With the emergence of drug-resistance in chicken coccidia, it is imperative develop new drugs. Cyclin-dependent kinases (CDKs) regulate cell cycle progression numerous organisms acting as key molecular switches. Results: In present study, a diclazuril anticoccidiosis animal model was established and CDK-related kinase 2 (CRK2) second-generation merozoite E. ( Et...

10.21203/rs.3.rs-28965/v1 preprint EN cc-by Research Square (Research Square) 2020-08-14
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