A5101627406- Traditional Chinese Medicine Studies
- Alzheimer's disease research and treatments
- Ginseng Biological Effects and Applications
- Identification and Quantification in Food
- Pharmacological Effects of Natural Compounds
- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Analysis
- Natural product bioactivities and synthesis
- Medical Research and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Medicinal Plants and Bioactive Compounds
- Metabolomics and Mass Spectrometry Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Medicinal Plant Pharmacodynamics Research
- Sleep and Wakefulness Research
- Health and Well-being Studies
- Dementia and Cognitive Impairment Research
- Healthcare and Venom Research
- Sleep and related disorders
- Infant Health and Development
- Tryptophan and brain disorders
- Neurological Disease Mechanisms and Treatments
- Nephrotoxicity and Medicinal Plants
- Genomics and Phylogenetic Studies
- Simulation and Modeling Applications
Hubei University of Chinese Medicine
2016-2025
ShanghaiTech University
2024
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2023-2024
Henan Agricultural University
2013-2024
Second Hospital of Shandong University
2020-2023
Shaanxi University of Chinese Medicine
2023
Qingdao Municipal Hospital
2018-2023
Hangzhou Normal University
2023
Qingdao University
2018-2023
Ministry of Agriculture and Rural Affairs
2021
Long non-coding RNA (lncRNA) and exosomes are involved in the pathological process of Alzheimer's disease (AD), changes which usually first observed entorhinal cortex hippocampus. The aim present study was to determine whether measurement plasma exosomal lncRNA combined with image data hippocampus could be used as a biomarker AD. A total 72 patients AD 62 controls were recruited, expression levels several lncRNAs assessed. Of recruited participants, 22 26 received brain 3D‑BRAVO sequence...
Traditional Chinese medicine (TCM) is practiced in the health care system for more than 2,000 years. In recent years, herbal medicines, which are used to treat Alzheimer′s disease (AD) China based on TCM or modern pharmacological theories have attracted considerable attention. this paper, we discuss etiology and pathogenesis of AD, therapy, extracts treatment AD. There evidence suggest that therapy may offer certain complementary cognitive benefits herb advantages with multiple target...
ABSTRACT Thymol (THY) is a natural antioxidant and antimicrobial; however, its biological activity application in the food pharmaceutical fields are limited due to low water solubility volatility. In this study, inclusion complexes of cationic‐β‐cyclodextrin‐THY (C‐β‐CD‐THY) were prepared by using aqueous stirring method. Then UV–Vis spectra, FT‐IR, NMR, DSC, XRD SEM data collected characterise structure morphology complexes. Phase experiments showed better solubilisation effect C‐β‐CD‐THY...
The purpose of this study is to analyze the relationship between psychological richness and innovative performance knowledge workers, as well mediating roles self-expansion self-efficacy in relationship. This collected 443 questionnaire surveys from employees Chinese enterprises conducted data analysis hypothesis testing using AMOS 26.0 SPSS 27.0. results indicate that has a significantly positive impact on play significant chain role process. Prior studies have primarily focused how hedonic...
Rhizoma Paridis (Chonglou) is a commonly used and precious traditional Chinese medicine. Paris polyphylla Smith var. yunnanensis (Franch.) Hand. -Mazz. chinensis Hara are the two main sources of Chonglou under monograph in Pharmacopoeia. In local marketplace, however, this medicine prone to be accidentally contaminated, deliberately substituted or admixed with other species that similar shape color. Consequently, these adulterations might compromise quality control result considerable health...
Herbgenomics provides a global platform to explore the genetics and biology of herbs on genome level. Panax ginseng C.A. Meyer is an important medicinal plant with numerous pharmaceutical effects. Previous reports mainly discussed transcriptome at organ However, based mass spectrometry imaging analyses, ginsenosides varied among different tissues. In this work, root was separated into three tissues-periderm, cortex stele-each for five duplicates. The chemical analysis were conducted...
Seed is not only the main reproductive organ of most herbal plants but also an important part Traditional Chinese Medicine (TCM). TCMs possess medicinal properties and have been widely used as components pharmaceutical products. In parallel with increasing popularity accessibility seeds products in recent years, numerous substitutes adulterants appeared on market. Due to small volume similar appearances many seed TCMs, they are very difficult accurately identify constituent plant species...
To explore the mechanism of reinforcing kidney-essence, removing phlegm, and promoting mental therapy in treating Alzheimer's disease (AD). Sixty patients with AD Wuhan No.1 Hospital Traditional Chinese Medicine for Geriatrics from May 2009 to April 2011 were randomly divided into two groups, 30 each group. Patients Bushenhuatanyizhi group (BHY group) took BHY instant granules (6 g, twice per day). control piracetam (0.8 3 times There twelve weeks a course. Changes mini-mental state...
Mu-tong (Akebiae Caulis) is a traditional Chinese medicine commonly used as diuretic and antiphlogistic. A common adulterant of Guan-mu-tong (Aristolochiae Manshuriensis Caulis), which derived from the stem Aristolochia manshuriensis Komarov, contains carcinogenic aristolochic acids. We an alternative technique, loop-mediated isothermal amplification (LAMP), to differentiate because LAMP quick, highly sensitive, specific. designed set four primers (G-F3, G-B3, G-FIP, G-BIP) loop primer...
In order to remove zearalenone (ZEA) detriment—Bacillus subtilis, Candida utilis, and cell-free extracts from Aspergillus oryzae were used degrade ZEA in this study. The orthogonal experiment vitro showed that the degradation rate was 92.27% (p < 0.05) under conditions Bacillus subtilis SP1, SP2 mixed together at 0.5%, 1.0%, 1.0%. When combined with above probiotics a ratio of 2:1 make mycotoxin-biodegradation preparation (MBP), reached 95.15% 0.05). further investigate MBP effect on...
In the recent years, a wide range of metabonomic technologies are widely used in modern research traditional chinese medicine (TCM). At present, most prevailing methods for TCM mainly nuclear magnetic resonance (NMR), gas chromatography-mass spectrometry (GC-MS), and liquid (LC-MS). With these techniques, metabonomics will help to understand syndromes, efficacy toxicity TCM. However, every analytical technique has its advantages drawbacks, there exist some obstacles applications on So, we...
The deposition of amyloid beta (A
The theory of lung being connected with large intestine, which is a major topic in Traditional Chinese Medicine (TCM), has guided clinical practice for thousands years China.In this study, we analyzed the history, main contents, application, and material basis theory, to attempt improve potential significance "lung intestine" China.The intestine was first described "Huang Di Nei Jing", formed one basic theories TCM. For years, majority TCM practitioners explored continuously, leading its...
Chrysanthemum indicum, an important medicinal plant of Asteraceae, had a long history in use for medicine China. In this study, the complete chloroplast genome C. indicum was sequenced by 454 sequencing platform, and structure obtained also analyzed. The 150 972 bp length pair inverted repeats (IR, 24 956 bp) separated large (LSC, 82 741 small single copy (SSC, 18 319 regions. Its total GC content 37.48%. There were 126 genes including 83 protein-coding genes, 35 tRNAs eight rRNAs...
To explore the mechanisms of volatiles Wendan granule (WDG) for treatment Alzheimer's disease, network pharmacology method integrating absorption, distribution, metabolism, and excretion (ADME) screening, target fishing, constructing, pathway analysing, correlated diseases prediction was applied.Twelve small molecular compounds WDG were selected as objects from 74 with relative abundances above 2 %, their ADME parameters collected Traditional Chinese Medicine Systems Pharmacology platform...