- Palliative Care and End-of-Life Issues
- Intensive Care Unit Cognitive Disorders
- Family and Patient Care in Intensive Care Units
- Potassium and Related Disorders
- Healthcare Decision-Making and Restraints
- Heart Failure Treatment and Management
- Cardiac Arrest and Resuscitation
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- COVID-19 and Mental Health
- Hip and Femur Fractures
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiac, Anesthesia and Surgical Outcomes
- Electrolyte and hormonal disorders
- Frailty in Older Adults
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrhythmias and Treatments
- Nutrition and Health in Aging
- Ethics and Legal Issues in Pediatric Healthcare
- Biomedical and Chemical Research
- Ethics in medical practice
- Infant Development and Preterm Care
- Thermal Regulation in Medicine
- Ethics in Clinical Research
- Antiplatelet Therapy and Cardiovascular Diseases
University of Hong Kong
2014-2024
Chinese University of Hong Kong
2021
Queen Mary Hospital
2014-2016
University of Birmingham
2014
Background and Purpose— Little is known about the impact of quality anticoagulation control, as reflected by time in therapeutic range (TTR), on effectiveness safety warfarin therapy Chinese patients with atrial fibrillation. We investigated risks ischemic stroke intracranial hemorrhage (ICH) relation to at various TTRs a real-world cohort fibrillation receiving compared those dabigatran, aspirin, no therapy. Methods— This an observational study. Results— Of 8754 CHA 2 DS -VASc ≥1 (79.5±9.2...
Dabigatran, an oral direct thrombin inhibitor, possesses several advantages over warfarin that can in principle simplify the management of stroke prevention atrial fibrillation (AF). Nonetheless it remains unclear whether these translate to clinical practice and encourage long-term therapy. The objective was describe dabigatran therapy for AF identify risk factors discontinuation therapy.We studied 467 consecutive Chinese patients (72 ± 11 years, male: 53.8%) with a mean CHA2DS2-VASc score...
Early intensive care unit (ICU) protocolized rehabilitative programs have been described previously, yet with differing starting time points and mostly on mechanically ventilated patients. We extended the concept to all admitted ICU patients investigate efficacy of early mobilization in improving mobility critically ill, address issues surrounding timing intensity an program.Prospective cohorts consecutively before-and-after (control, n=92; intervention, n=90) introduction program a single...
Background: Patients with severe euvolemic hyponatremia can be challenging to treat, and the COVID-19 pandemic has added complexity of situation. Methods: Data were collected from all patients treated in a local intensive care unit (ICU) protocolized proactive desmopressin plus 3% saline (PD-3 S) approach March 2022. Results: Six protocol, whose initial serum sodium level (SNa) ranged 98 108 mmol/L. SNa one patient dropped further due delayed initiation PD-3 S because access block. But...
Abstract Aims Little is known about the relative importance of body volume and haemodynamic parameters in development worsening renal function acutely decompensated heart failure (ADHF). To study relationship between parameters, water content patients with reduced ejection fraction (HFrEF) hospitalised for ADHF. Methods results This prospective observational involved 51 consecutive HFrEF (age: 73±14 years, male: 60%, left ventricular fraction: 33.3%±9.9%) Echocardiographic-determined...