Tobien H.C.M.L. Schreuder
A5091210398- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular Health and Disease Prevention
- MRI in cancer diagnosis
- Orthopedic Surgery and Rehabilitation
- Cardiac, Anesthesia and Surgical Outcomes
- Advanced X-ray and CT Imaging
- Peripheral Artery Disease Management
- Renal and Vascular Pathologies
- Neurosurgical Procedures and Complications
- Atrial Fibrillation Management and Outcomes
- Peripheral Nerve Disorders
- Congenital Heart Disease Studies
- Advanced MRI Techniques and Applications
- Cerebrospinal fluid and hydrocephalus
- Elbow and Forearm Trauma Treatment
Atrium Medisch Centrum Parkstad
2015-2025
Zuyderland Medisch Centrum
2017-2024
Health and Education Research Management and Epidemiologic Services (United States)
2021
Hermes Arzneimittel (Germany)
2021
Maastricht University
2017
Maastricht University Medical Centre
2017
High blood pressure (BP) is associated with poor outcome and the occurrence of symptomatic intracranial hemorrhage in acute ischemic stroke. Whether BP influences benefit or safety intra-arterial treatment (IAT) not known. We aimed to assess relation functional outcome, effect IAT.This a post hoc analysis MR CLEAN (Multicenter Randomized Clinical Trial Endovascular Treatment Acute Ischemic Stroke Netherlands). was measured at baseline, before IAT stroke unit admission. estimated association...
The utility of computed tomographic perfusion (CTP)-based patient selection for intra-arterial treatment acute ischemic stroke has not been proven in randomized trials and requires further study a cohort that was selected based on CTP. Our objective to the relationship between CTP-derived parameters outcome effect patients with because proximal intracranial arterial occlusion.We included 175 who underwent CTP Multicenter Randomized Clinical Trial Endovascular Treatment Acute Ischemic Stroke...
A carotid web (CW) is a shelf-like lesion along the posterior wall of internal artery bulb and an underrecognized cause young stroke. Several studies suggest that patients with symptomatic CW have high risk recurrent stroke, but high-quality data are lacking.To assess 2-year stroke in CW.A comparative cohort study used from MR CLEAN trial (from 2010-2014) Registry 2014-2017). Data were analyzed September 2020. The nationwide prospective multicenter on endovascular treatment (EVT) large...
Background and Purpose— If a relationship between stroke etiology thrombus computed tomography characteristics exists, assessing these in clinical practice could serve as useful additional diagnostic tool for the identification of subtype. Our purpose was to study association patients with acute ischemic due large vessel occlusion. Methods— For 1429 consecutive enrolled MR CLEAN Registry, we determined cause defined by TOAST (Trial ORG 10172 Acute Stroke Treatment) criteria. The hyperdense...
We evaluated data from all patients in the Netherlands who underwent endovascular treatment for acute ischemic stroke past 3.5 years, to identify nationwide trends time and procedural success, assess their effect on clinical outcomes.We included with proximal occlusions of anterior circulation second first cohorts MR CLEAN (Multicenter Randomized Clinical trial Endovascular Treatment Acute Ischemic Stroke Netherlands) Registry (March 2014 June 2016; 2016 November 2017, respectively)....
The Plaque at RISK (PARISK) study demonstrated that patients with a carotid plaque intraplaque hemorrhage (IPH) have an increased risk of recurrent ipsilateral ischemic cerebrovascular events. It was previously reported symptomatic plaques IPH showed higher signal intensity ratios (SIR) and larger volumes than asymptomatic plaques. We explored whether SIR volume are associated future events beyond the presence IPH. TIA stroke mild-to-moderate stenosis IPH-positive (n=89) from PARISK were...
Optimal blood pressure (BP) targets before endovascular treatment (EVT) for acute ischemic stroke are unknown. We aimed to assess the relation between admission BP and clinical outcomes successful reperfusion after EVT.We used data from MR CLEAN (Multicenter Randomized Controlled Trial of Endovascular Treatment Acute Ischemic Stroke in Netherlands) Registry, an observational, prospective, nationwide cohort study patients with treated EVT routine practice Netherlands. Baseline systolic (SBP)...
Spontaneous intracerebral hemorrhage (ICH) in the cerebellum has a poor short-term prognosis, whereas data on long-term case fatality and recurrent vascular events are sparse. Herewith, we aimed to assess recurrence rate of after first cerebellar ICH.
Objectives Carotid plaque vulnerability is a strong predictor of recurrent ipsilateral stroke, but differentiation components using conventional computed tomography (CT) suboptimal. The aim our study was to evaluate the ability dual-energy CT (DECT) characterize atherosclerotic carotid based on effective atomic number and electron density magnetic resonance imaging (MRI) and, where possible, histology as reference standard. Materials Methods Patients with recent cerebral ischemia ≥2-mm...
To investigate the effect of conscious sedation (CS) on functional outcome and complication rates after intra-arterial treatment (IAT) for acute ischemic stroke (AIS) compared to use local anesthesia (LA) at puncture site only.Patients undergoing IAT AIS with CS or LA in Erasmus University Medical Center from March 2014 June 2016 were included analysis. The primary was score ordinal modified Rankin Scale (mRS). We by logistic regression covariate adjustment using propensity scoring.In 146...
Introduction: Endovascular thrombectomy (EVT) procedures and workflow have evolved over the years. We examined trends in patient characteristics, EVT techniques outcomes 5 years Netherlands. Patients methods: Data from MR CLEAN Registry (2014–2018) were analysed, including patients treated with for anterior circulation acute ischaemic stroke (AIS). grouped by year of inclusion except linear regression analysis where date was used. Baseline predicted probability poor outcome (modified Rankin...
Cerebral small vessel disease (SVD) is associated with cognitive impairment. This may be because of decreased microstructural integrity and microvascular perfusion, but data on these relationships are scarce. We determined the relationship between cognition perfusion in SVD patients, using intravoxel incoherent motion imaging-a diffusion-weighted magnetic resonance imaging technique designed to determine simultaneously.Seventy-three patients 39 controls underwent neuropsychological...
Background and Purpose: Thrombectomy with stent retriever direct aspiration are equally effective in the endovascular treatment of anterior circulation acute ischemic stroke. We report efficacy safety initial technique per occlusion segment. Methods: For this study, we analyzed data from MR CLEAN Registry, a prospective, observational study all centers that perform therapy Netherlands. used ordinal logistic regression analysis to compare clinical technical results first line thrombectomy...
Background and Purpose— The use of oral anticoagulants (OAC) is considered a contra-indication for intravenous thrombolytics as acute treatment ischemic stroke. However, little known about the risks benefits endovascular in patients on prior OAC. We aim to compare outcomes after between with without Methods— Data stroke caused by an intracranial anterior circulation occlusion, included nationwide, prospective, MR CLEAN Registry March 2014 November 2017, were analyzed. Outcomes interest...
Background and Purpose: Optimal blood pressure (BP) management in the acute phase of ischemic stroke remains an unresolved issue. It is uncertain whether guidelines for BP during after intravenous alteplase can be extrapolated to endovascular treatment (EVT) due large artery occlusion anterior circulation. We evaluated associations between systolic (SBP) first 6 hours following EVT functional outcome as well symptomatic intracranial hemorrhage. Methods: Patients 8 MR CLEAN (Multicenter...
Cerebral white matter lesions (WMLs) have been associated with a greater risk of poor functional outcome after ischemic stroke. We assessed the relations between WML burden and radiological clinical outcomes in patients treated endovascular treatment routine practice.We analyzed data from MR CLEAN Registry (Multicenter Randomized Controlled Trial Endovascular Treatment for Acute Ischaemic Stroke Netherlands)—a prospective, multicenter, observational cohort study Netherlands. WMLs were graded...
Background and Purpose- Intravenous administration of heparin during endovascular treatment for ischemic stroke may improve outcomes. However, risks benefits this adjunctive therapy remain uncertain. We aimed to evaluate periprocedural intravenous use in Dutch intervention centers assess its efficacy safety. Methods- Patients registered between March 2014 June 2016 the MR CLEAN Registry (Multicenter Randomized Clinical Trial Endovascular Treatment Acute Ischemic Stroke), including all...
Background and Purpose: Ischemic brain tissue damage in patients with acute ischemic stroke, as measured by the Alberta Stroke Program Early CT Score (ASPECTS) may be more impactful older than younger patients, although this has not been studied. We aimed to investigate a possible interaction effect between age ASPECTS on functional outcome stroke undergoing endovascular treatment, compared reperfusion benefit across subgroups. Methods: Patients from MR CLEAN Registry (Multicenter Randomized...
Data on oral anticoagulant-related (OAC) intracerebral hemorrhage (ICH) incidence are scarce. Most studies time trends were performed before the introduction of Direct Oral Anticoagulants (DOACs). Between 2008 and 2018, number OAC-users in Netherlands increased by 63%, with DOAC-users almost equaling that Vitamin K Antagonists (VKA)-users. We aimed to determine recent total OAC-related ICH assess changes over last decade, including effect DOAC introduction.All adult non-traumatic patients...
Abstract Introduction The best treatment strategy for mild ulnar neuropathy at the elbow (UNE) is not known, due to lack of trials comparing surgery vs conservative treatment. Methods We recruited patients with clinical symptoms and signs UNE an electrophysiologically or sonographically confirmed diagnosis. Patients were randomly allocated either in situ decompression primary outcome was proportion subjective symptom improvement short‐term (3 months) long‐term (6‐12 follow‐up. Results One...
Before 2015, endovascular treatment (EVT) for acute ischemic stroke was considered a promising option. Based on limited evidence, it performed in several dedicated centers worldwide selected patients. Since EVT patients with intracranial large vessel occlusion has quickly been implemented as standard many countries worldwide, supported by the revised international guidelines based solid evidence from multiple clinical trials. We describe development use of Netherlands before, during, and...