Oliver G. Denton
- Genetic factors in colorectal cancer
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Surgical Simulation and Training
- Augmented Reality Applications
- Botulinum Toxin and Related Neurological Disorders
- Academic Writing and Publishing
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Anatomy and Medical Technology
- Nasal Surgery and Airway Studies
- Ear Surgery and Otitis Media
- Virtual Reality Applications and Impacts
- Sinusitis and nasal conditions
- 3D Printing in Biomedical Research
- Periodontal Regeneration and Treatments
- Enhanced Recovery After Surgery
- Surgical site infection prevention
University of Strathclyde
2024
NHS Greater Glasgow and Clyde
2020-2024
University of Glasgow
2024
NHS Lanarkshire
2022
Monklands Hospital
2022
Glasgow Royal Infirmary
2020-2021
Cardiff University
2019-2021
Pathogenic variants affecting MLH1, MSH2, MSH6, and PMS2 cause Lynch syndrome result in different but imprecisely known cancer risks. This study aimed to provide age organ-specific risks according gene gender determine survival after cancer.We conducted an international, multicenter prospective observational using independent test validation cohorts of carriers class 4 or 5 variants. After the were merged providing 6350 participants 51,646 follow-up years.There 1808 prospectively observed...
PurposeThis study aimed to report the uptake of hysterectomy and/or bilateral salpingo-oophorectomy (BSO) prevent gynaecological cancers (risk-reducing surgery [RRS]) in carriers pathogenic MMR (path_MMR) variants.MethodsThe Prospective Lynch Syndrome Database (PLSD) was used investigate RRS by a cross-sectional 2292 female path_MMR aged 30–69 years.ResultsOverall, 144, 79, and 517 underwent risk-reducing hysterectomy, BSO, or both combined, respectively. Two-thirds procedures before 50...
Abstract Objective Rate of learning is often cited as a deterrent in the use endoscopic ear surgery. This study investigated curves novice surgeons performing simulated surgery using either an endoscope or microscope. Methods A prospective multi-site clinical research was conducted. Seventy-two medical students were randomly allocated to microscope group, and performed 10 myringotomy ventilation tube insertions. Trial times used produce curves. From these, slope (learning rate) asymptote...
Acute recurrent tonsillitis is a chronic, biofilm-related infection that significant burden to patients and healthcare systems. It often treated with repeated courses of antibiotics, which contributes antimicrobial resistance. Studying biofilms key understanding this disease. In vitro modelling using 3D bioprinted hydrogels promising approach achieve this. A novel gelatin-PEGDA pseudomonas fluorescens-laden bioink was developed in hydrogel construct fabricated computer-aided design mimic the...
Abstract Background Three-dimensional endoscopes provide a stereoscopic view of the operating field, facilitating depth perception compared to two-dimensional systems, but are not yet widely accepted. Existing research addresses performance and preference, there no studies that quantify anatomical orientation in endoscopic ear surgery. Methods Participants ( n = 70) were randomised starting with either or three-dimensional endoscope system perform one two tasks: using labelled printed...
Abstract Introduction Surgical site infections (SSI) are responsible for one third of all inpatient and associated with increased morbidity extended hospital stay. The colorectal department at Glasgow Royal Infirmary introduced the Jubilee dressing method in August 2019 aim reducing SSI incidence. Method Closed loop audit elective laparotomies pre- post-introduction (March – July & December 2019). Literature reviews informed selection baseline characteristics relevant to SSI. Analysis by...