A5089360004- Preterm Birth and Chorioamnionitis
- Pregnancy-related medical research
- Neonatal Respiratory Health Research
- Maternal and Perinatal Health Interventions
- Assisted Reproductive Technology and Twin Pregnancy
- Pelvic floor disorders treatments
- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- Maternal and fetal healthcare
- Reproductive System and Pregnancy
- Reproductive tract infections research
- Infant Nutrition and Health
- Adventure Sports and Sensation Seeking
- Neonatal and fetal brain pathology
- Cervical Cancer and HPV Research
- Physical Education and Sports Studies
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Congenital Heart Disease Studies
- Fetal and Pediatric Neurological Disorders
- Urological Disorders and Treatments
- Neuroscience of respiration and sleep
- Immune Response and Inflammation
- Trauma and Emergency Care Studies
- Youth Development and Social Support
Oregon Health & Science University
2013-2024
Faculdade de Medicina do ABC
2024
Universidade Estadual Paulista (Unesp)
2011-2016
In-Q-Tel
2015
J.P. Morgan
2015
Centro Universitário de Jales
2011
Methodist University of Piracicaba
2007
Universidade de São Paulo
2005-2007
Thomas Jefferson University
2002-2006
Jefferson College
2002-2004
Cell-free DNA (cfDNA) testing for fetal trisomy is highly effective among high-risk women. However, there have been few direct, well-powered studies comparing cfDNA with standard screening during the first trimester in routine prenatal populations.In this prospective, multicenter, blinded study conducted at 35 international centers, we assigned pregnant women presenting aneuploidy 10 to 14 weeks of gestation undergo both (with measurement nuchal translucency and biochemical analytes)...
Abstract Inflammation is a crucial step for the wound healing process. The effect of linoleic and oleic acids on inflammatory response skin during process release pro‐inflammatory cytokines by rat neutrophils in vitro was investigated. A dorsal surface adult rats performed fatty were then topically administered. Both increased tissue mass. total protein DNA contents wounds treatment with acid. treatments did not affect vascular permeability. However, number wounded area air pouches thickness...
Os mecanismos envolvidos no processo de reparo tecidos estão revisados nesse trabalho. O cicatrização ocorre fundamentalmente em três fases: inflamação, formação tecido granulação e deposição matriz extracelular remodelação. eventos celulares tissulares cada uma dessas fases descritos discutidos. mediadores químicos correlacionados com os do as células envolvidas. Especial ênfase é dada à participação dos fatores crescimento.
Development of effective prevention and treatment strategies for pre-eclampsia is limited by the lack accurate methods identification at-risk pregnancies. We performed small RNA sequencing (RNA-seq) maternal serum extracellular RNAs (exRNAs) to discover verify microRNAs (miRNAs) differentially expressed in patients who later developed pre-eclampsia. Sera collected from 73 cases 139 controls between 17 28 weeks gestational age (GA), divided into separate discovery verification cohorts, are...
The purpose of this study was to determine the efficacy sonographically indicated cerclage in multiple gestations with sonographic evidence short cervical length (CL).Between 1996 and 2002, all undergoing serial CL determinations second trimester were identified 2 separate institutions. Cervical lengths measured transvaginal probes (4-8 MHz). Short defined as a closed 2.5 cm or less. When before 24 weeks, group underwent via modified Shirodkar technique; control patients placed on bed rest...
The transition from pregnancy into parturition is physiologically directed by maternal, fetal and placental tissues. We hypothesize that these processes may be reflected in maternal physiological metrics. enrolled pregnant participants the third-trimester (n = 118) to study continuously worn smart ring devices monitoring heart rate, rate variability, skin temperature, sleep physical activity negative temperature coefficient, 3-D accelerometer infrared photoplethysmography sensors. Weekly...
Obstet Gynecol Surv 2015;70(8):483–484 While cell-free DNA (cfDNA) testing for fetal aneuploidy has been shown to have a high detection rate trisomy, most large studies included only high-risk populations. This blinded, prospective study tested the performance of screening with cfDNA common trisomies in general population.
In Brief BACKGROUND Uterine artery embolization is an increasingly popular alternative to hysterectomy and myomectomy as a treatment for uterine leiomyoma. Whether this procedure safe women desiring future fertility controversial. CASES A primigravida who had previously undergone premature rupture of membranes at 24 weeks. She cesarean delivery 28 weeks, which was followed by atony requiring hysterectomy. delivered appropriately grown dichorionic twins 36 An analysis the 50 published cases...
We sought to estimate the effect of indomethacin on duration pregnancy in women with dilated cervix between 140/7 256/7 weeks. Demographics, risk factors, and outcomes were compared weeks a ≥ 1 cm who received versus no therapy, stratified for cerclage. Primary outcome was interval from presentation until delivery. Of 222 singleton gestations, 68 (31%) indomethacin. In unadjusted adjusted analyses, significant differences observed delivery preterm birth < 28, 32, or 35 comparing groups, even...
Recent evidence suggests that exposure to intrauterine inflammation causes acute fetal brain injury and is linked a spectrum of neurobehavioral disorders. In rodent model induced by lipopolysaccharide (LPS) in utero, activated microglia can be detected the hippocampus offspring survivors, as late 60 days postnatal (DPN). Given important for learning memory, these results suggest utero underlies long-term cognitive deficits observed children/survivors. An established mouse LPS-induced was...
Objective: Proteomic analysis of four cervical-vaginal fluid (CVF) proteins to identify biomarkers recurrent preterm birth (rPTB) in at-risk women prior onset labor.