A5100455372- Tryptophan and brain disorders
- Nicotinic Acetylcholine Receptors Study
- Advanced Combustion Engine Technologies
- Spine and Intervertebral Disc Pathology
- IoT and Edge/Fog Computing
- Neurotransmitter Receptor Influence on Behavior
- Vehicle emissions and performance
- Genetics and Neurodevelopmental Disorders
- Spinal Fractures and Fixation Techniques
- Neuroscience and Neuropharmacology Research
- Time Series Analysis and Forecasting
- Migraine and Headache Studies
- Catalytic Processes in Materials Science
- Anomaly Detection Techniques and Applications
- Epigenetics and DNA Methylation
- Stress Responses and Cortisol
- Cervical and Thoracic Myelopathy
- Spinal Hematomas and Complications
- Age of Information Optimization
- Orthopedic Infections and Treatments
- Ophthalmology and Eye Disorders
- Circadian rhythm and melatonin
- Forensic Toxicology and Drug Analysis
- Advanced Computing and Algorithms
- Pancreatic function and diabetes
Xi'an Jiaotong University
2015-2024
Xi'an Honghui Hospital
2016-2023
Centre for Addiction and Mental Health
2015
Abstract The translational defect has emerged as a common feature of neurological disorders. Studies have suggested that alterations between opposing and balanced synaptic protein synthesis turnover processes could lead to abnormalities, followed by depressive symptoms. Further studies link this phenomenon with eIF4E TrkB/BDNF signaling. However, the interplay signaling in presence neuroinflammation is yet be explored. To illuminate role activities within LPS-induced depression symptomology,...
Abstract Aim Psilocin is an active metabolite form of psilocybin and exerts psychoactive effects. Recent studies suggest that psilocin may have regulatory effects on abuse drugs, but the mechanisms remain unclear. In this study, we want to explore methamphetamine (METH)‐induced alterations behavior in mice its molecular mechanisms. Methods Acute METH administration model conditioned place preference (CPP) were used investigate METH‐induced behavior. Western blot was detect expression...
Depression is often linked to inflammation in the brain. Researchers have been exploring ways reduce this improve depression symptoms. One potential target a protein called RIPK1, which known contribute brain inflammation. However, it's unclear how RIPK1 influences depression. Our study aims determine whether inhibition could alleviate neuroinflammation-associated and elucidate its underlying mechanisms. To investigate our research objectives, we established neuroinflammation mouse model by...
The use of electronic cigarette (e-cigarette) has been increasing dramatically worldwide. More than 8,000 flavors e-cigarettes are currently marketed and menthol is one the most popular flavor additives in nicotine delivery systems (ENDS). There a controversy over roles social behavior, little known about potential impacts flavorings ENDS. In our study, we aimed to investigate effects ENDS on behavior long-term vapor-exposed mice with daily intake limit, underlying immunometabolic changes...
Abstract A recent genome-wide meta study suggested that rs67338227 in the FHL5 gene and rs10456100 KCNK5 are associated with migraine from 27 population-based cohorts excluding Chinese population. Given without aura (MO) is most common subtype of migraine, our aim was to systematically investigate relationship variants genes susceptibility MO provide clues as nature mechanisms involved etiology migraine. total 3306 subjects including 1042 patients 2264 controls were recruited for discovery...
Background: Methamphetamine use disorder (MUD) has become a global problem due to the highly addictive nature of methamphetamine. Earlier research have demonstrated that PROK2 functions as compensatory and protective response against neurotoxic stress by stimulating astrocyte reactivity. The aim our study was evaluate correlation between gene both MUD risk susceptibility craving scale in Chinese Han population. Methods: A total 5,282 participants (1,796 patients 3,486 controls) were...
Wireless devices (WDs) connected to the Internet usually have limited computing capacity and battery power. Task offloading enables these support applications with complex tasks, reduce task execution delay save We consider a device-to-device (D2D) assisted mobile edge (MEC) system, in which WDs can not only offload tasks MEC server through cellular link, but also nearby idle D2D link. However, hybrid mode environment is non-stationary, wireless channel states workloads of auxiliary (ADs)...
Abstract Background: Cervical disc replacement (CDR) is considered to be an effective alternative treatment anterior cervical discectomy and fusion (ACDF). However, the use of most artificial prostheses can lead complications due high morphological dimensional mismatch with human neck anatomy. Objective: By comparing clinical efficacy new 3D printed ACDF in treating spondylosis, study value appropriate dimensional. Methods: This was a retrospective analysis 58 patients single-segment...