A5012016987- Vascular Malformations and Hemangiomas
- Vascular Malformations Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Vascular Tumors and Angiosarcomas
- Tumors and Oncological Cases
- Central Venous Catheters and Hemodialysis
- Dermatologic Treatments and Research
- Bone fractures and treatments
- Bone and Joint Diseases
- Renal and related cancers
- Mesenchymal stem cell research
- Cardiac Valve Diseases and Treatments
- Peroxisome Proliferator-Activated Receptors
- Wound Healing and Treatments
- Burn Injury Management and Outcomes
- Vascular anomalies and interventions
- Facial Rejuvenation and Surgery Techniques
- Cardiac Structural Anomalies and Repair
- Neurofibromatosis and Schwannoma Cases
- Soft tissue tumor case studies
- Renal cell carcinoma treatment
- Diabetic Foot Ulcer Assessment and Management
- Breast Implant and Reconstruction
- Genetic and rare skin diseases.
Nanjing University
2014-2025
Nanjing General Hospital of Nanjing Military Command
2016-2025
Southern Medical University
2018-2025
Nanjing Medical University
2011-2025
Nanjing University of Chinese Medicine
2024-2025
Southeast University
2019-2025
Guangzhou Medical University
2025
Second Affiliated Hospital of Guangzhou Medical University
2025
Weatherford College
2024
WuXi AppTec (China)
2023
Purpose: Hydrogen is a proven novel antioxidant that selectively reduces hydroxyl radicals. In this study, we investigated the effects of hydrogen-rich saline solution on prevention renal injury induced by ischemia/reperfusion (I/R) and function recovery. Methods: A rat model I/R was 45 min occlusion left pedicle, followed 108 h reperfusion. The right kidney surgically removed. Then, 0.9% NaCl (1 ml/kg) or (HRSS) injected into abdominal cavity at four hours intervals. We assessed influence...
ObjectivesThe objectives of this study were to determine species distribution and in vitro antifungal susceptibility Candida isolates identified the multicentre China-SCAN invasive infection (ICI) intensive care units (ICUs) across China.
Background: Cutaneous melanoma is a highly malignant tumor which tends to metastasize in the early stage and leads poor prognosis. Hematogenous lymphatic metastasis are common dissemination of melanoma. Rapamycin, an mTOR inhibitor, was reported have anti-angiogenic anti-lymphangiogenic properties. Aim: The aim this study investigate if rapamycin can inhibit formation blood vessels Methods: A xenograft model generated by subcutaneously transplanting A375 human cells into back immunodeficient...
The peroneal artery perforator flap is widely used to repair deep defects in the distal lower leg and ankle. However, success of transplantation depends on accurate location perforators, which can be a challenge due potential vascular damage anatomical variations. This study utilizes digital subtraction angiography high-frequency ultrasound clarify features its perforators accurately locate these thereby improving preoperative design clinical outcomes. Peroneal sequential flaps were employed...
Background ATP11A encodes an integral-membrane type IV P-type-adenosine triphosphatase that plays important role in neural development by maintaining membrane lipid asymmetry. de novo heterozygous missense variants have been reported to be associated with hypomyelinating leukodystrophy; however, the neurological symptoms of patients are often varying. In this study, we aimed explore relationship between and epilepsy. Methods Trio-based whole-exome sequencing was performed on focal Multiple...
ABSTRACT Background Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue malignancy with aggressive growth. Objective To summarize the surgical treatment and results of DFSP based on case series literature review. Methods Seventeen cases were analyzed retrospectively at our hospital from June 2016 to December 2022, including 14 males 3 females. All these treated by wide local excision negative margins. Postoperative follow‐up was performed observe recurrence, survival, effect wound...
Background and Objective: Arteriovenous malformations (AVMs) in soft tissues are uncommon congenital vascular malformations, which challenging to treat due the high flow, risk of uncontrollable bleeding, infiltrative growth. Surgical resection interventional embolization main treatment for AVMs. The authors aim summarize an individualized strategy treating AVMs achieve optimal outcome. Methods: medical records patients with tissue who were treated our center from January 2006 December 2023...
Infantile hemangioma grows quickly in the first year of life and regresses slowly to fibrofatty tissue during childhood; mesenchymal stem cells (MSCs) have been reported contribute this adipogenesis. Recent studies shown perivascular origin MSCs multiple organs. We hypothesized that might also reside region. isolated from proliferating by their selective adhesion plastic culture dishes. Mesenchymal bone marrow (BM-MSCs) foreskin-derived fibroblasts were used as controls. Flow cytometry...
Kaposiform hemangioendothelioma (KHE), a borderline tumor of endothelial origin, is associated with Kasabach-Merritt phenomenon, characterized by profound thrombocytopenia and consumptive coagulopathy resulting from the localized intravascular coagulation (LIC) in tumor. Previous studies have suggested that trapping blood components, including platelets, may underlie LIC KHE. However, more evidence needed to support this hypothesis. In study, one case Chinese infant KHE left arm was...
// Si-Ming Yuan 1, * , Yao Guo Qian Wang 1 Xu Min Hai-Ni Chen 2 and Wei-Min Shen Department of Plastic Surgery Vascular Biology Lab, Jinling Hospital, School Medicine, Nanjing University, Nanjing, Jiangsu 210002, China Surgery, Children's 210008, These authors have contributed equally to this work Correspondence to: Yuan, email: yuansm@163.com Keywords: infantile hemangioma; involution; mesenchymal stem cell; PPAR-γ; adipogenesis Received: August 08, 2017 Accepted: December 05, Published:...
The use of glucocorticoid in infantile hemangioma has remained the main stream for over 30 years. Intralesional corticosteroids got good effects small-size hemangioma. Here, we introduce a new compound glucocorticoids preparation, Diprospan. Diprospan 1 mL/ampoule contains betamethasone disodium phosphate 2 mg and dipropionate 5 mg. It is combination short-acting long-acting components.From January 2005 to December 2013, 57 children with were enrolled into this study. area tumor ranged from...
Infantile hemangioma can grow dramatically or typically locate on the face, which may lead to functional impairment, cosmetically disfiguring and exhibiting complications such as ulceration, bleeding, infection. Early intervention is necessary. In this study, authors chose individual treatment for different patients. From January 2012 December 2016, 185 patients with were enrolled into study. Lesion area ranged from 0.5 cm × 9 12 cm. The initial age 1 7 months an average of 3.9 months....
Bone morphogenetic protein-7 (BMP-7) and SOX9 are important transcription factors in chondrogenesis.In this study, we examined the biological function of adeno-associated virus (AAV)mediated BMP-7 double gene vitro co-transfection nucleus pulposus cells human degenerative intervertebral disc.Human disc were cultured subcultured for 5 generations.Using rAAV-BMP-7 rAAV-SOX9 AAV2-type AAV viruses, divided into 4 groups: blank normal, transfection, co-transfection.After 48 h, expression type II...
Functional human hepatocytes xenografted into the liver of mice can be used as a model system to study pharmacokinetics, infection hepatitis viruses, and efficacy vaccines. Significant levels xeno-repopulation have been reported in Fah−/−Rag2−/−Il2rg−/− mice. However, high mortality low breeding rate this may hinder its application. A new model, termed Fah−/−Nod/Scid mice, which combines advantages repopulation Fah−/− with ease xenotransplantation Nod/Scid was obtained by gradual...
Sir: Nipple inversion is generally a congenital disease, but it sometimes occurs after ductitis or breast operation.1 Anatomically, result of shortened lactiferous ducts, dysplasia nipple smooth muscles, and insufficient soft tissue. For years, doctors have preferred surgical procedures to narrow the neck consolidate bulk However, these may injure ductal system affect milk drainage,2 they induce scar formation around areola.3 We developed aspirator correct deformity in noninvasive way...
Soft tissue reconstruction of the distal lower leg and foot sole is a challenge for surgeons. In this article, we describe our experience outcomes with using medial plantar flap. From January 2007 to December 2017, 29 consecutive patients from department underwent soft defects over leg, heel forefoot flaps. Of patients, were located in (n = 8 [27.6%]), 14 [48.3%]) 7 [24.1%]). The mean follow-up period was 18.6 months, 28 (96.6%) survived completely. Lateral partial necrosis occurred one No...