- Chemokine receptors and signaling
- Endometrial and Cervical Cancer Treatments
- Immunotherapy and Immune Responses
- Cytokine Signaling Pathways and Interactions
- Head and Neck Cancer Studies
- Advances in Oncology and Radiotherapy
- Brain Metastases and Treatment
- Radiation Therapy and Dosimetry
- Bone health and treatments
- Head and Neck Surgical Oncology
- Advanced Radiotherapy Techniques
- Ovarian cancer diagnosis and treatment
- Bone Metabolism and Diseases
- Full-Duplex Wireless Communications
- Cervical Cancer and HPV Research
- Lung Cancer Research Studies
- Meningioma and schwannoma management
- Lung Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Neurofibromatosis and Schwannoma Cases
- HER2/EGFR in Cancer Research
- Medical Imaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Microplastics and Plastic Pollution
University of Messina
2022-2024
Morpho (United States)
2023
University of Verona
2022
Magna Graecia University
2017-2020
Purpose: To evaluate feasibility, toxicities, and clinical response in Stage IV patients treated with palliative “metabolism-guided” lattice technique. Patients Methods: From June 2020 to December 2021, 30 consecutive stage 31 bulky lesions were included this study. All received irradiation consisting of a spatially fractionated high radiation dose delivered spherical deposits (vertices, Vs) within the disease. The Vs placed at edges tumor areas different metabolisms PET exam following...
Protein hydrolysates obtained from discarded biomass can be further upgraded into high market value products, in the optic of a circular bioeconomy. In this work, residues cultivation alfalfa, soybean and rice, bovine wet blue shavings were fermented with mixed microbial cultures obtaining concentrations volatile fatty acid (up to 50 times compared original hydrolysate), mainly butyric acetic acid. This rich medium was used for growing bacterium Thauera sp., known producer...
Inflammatory breast cancer (IBC) is a rare, aggressive form of characterized by poor prognosis. The treatment requires multidisciplinary approach, with neoadjuvant chemotherapy, surgery, and radiation therapy (RT). Particularly, high doses conventional RT have been historically delivered in the adjuvant setting after chemotherapy mastectomy or as radical patients ineligible for surgery. Here, we report case 49-year-old woman patient IBC unsuitable surgery treated combination lattice...
To investigate the ability of radiotherapy (RT) to prolong progression-free survival (PFS) and report treatment-related toxicities among oligoprogressive metastatic Merkel cell carcinoma (mMCC) patients on avelumab. We retrospectively collected clinical data mMCC who underwent for limited progression Patients were categorized as primary or secondary immune refractory depending time onset resistance immunotherapy (at first subsequent follow-up visits after avelumab initiation). Pre- post-RT...
Locally advanced head and neck squamous cell carcinoma (LA-Hnscc) is a true therapeutical challenge in the modern era scientific community trying to face this with new strategies, including combinations of monoclonal antibodies radiation therapy. The aim study evaluate clinical outcomes LA-Hnscc patients unfit receive platinum-based chemotherapy, treated concurrent simultaneous integrated boost-intensity modulated radiotherapy (Sib-Imrt) + cetuximab (Ctx) daily practice.
Paragangliomas (PG) are rare neoplasms of neuroendocrine origin that tend to be highly vascularized, slow-growing, and usually sporadic. To date, common treatment options surgical resection (SR), with or without radiation therapy (RT), a watch-and-wait approach.
BACKGROUND Precision medicine is an emerging field that includes tumor-targeted delivery and tumor microenvironment. This review explores the synergistic potential of combining nano-drug systems with low radiation doses to achieve optimized therapeutic outcomes, particularly in context cancer treatment. Nanoparticle-based drug carriers offer precise targeted delivery, enhancing index anticancer agents. The use lower has become a focus oncology minimize off-target effects on healthy tissues...
Background: Paraneoplastic gastroparesis is a gastrointestinal syndrome that rarely precedes tumor diagnosis. To increase awareness of this rare clinical entity, we present case severe gastroparesis, which was later proven to be associated with thymoma. Case report: A 55-year old man had the sudden onset abdominal cramps and distension, early satiety postprandial nausea, acid regurgitation, belching, flatulence. He lost about 20 pounds. The physical imaging examination revealed stomach...
Abstract Th17 cells play a critical role in Multiple Myeloma (MM) microenvironment by triggering osteoclastogenic activity, that leads to severe skeleton damage. We have recently found directly promote osteoclast (OCL) differentiation and function via expression of RANKL. It has been demonstrated miRNAs are involved the cells. Murugaiyan et al. miR-21 promotes targeting depleting SMAD-7, negative regulator TGF-β signaling. Indeed, we able negatively modulate specific inhibitor (mir21i). The...