A5066263302- Asthma and respiratory diseases
- Peptidase Inhibition and Analysis
- Protease and Inhibitor Mechanisms
- Plant Pathogens and Fungal Diseases
- Genetic Associations and Epidemiology
- Indoor Air Quality and Microbial Exposure
- Genetic diversity and population structure
- Mycorrhizal Fungi and Plant Interactions
- Plant Diversity and Evolution
- Signaling Pathways in Disease
- Plant Pathogenic Bacteria Studies
- Forensic and Genetic Research
- Nutrition, Genetics, and Disease
- Horticultural and Viticultural Research
- Plant Reproductive Biology
- Forest Insect Ecology and Management
- Chromatin Remodeling and Cancer
- Climate Change and Health Impacts
- Insect Resistance and Genetics
- Studies on Chitinases and Chitosanases
- Cassava research and cyanide
- Advanced biosensing and bioanalysis techniques
- Plant Physiology and Cultivation Studies
- Respiratory and Cough-Related Research
- Air Quality and Health Impacts
Universidad de La Laguna
2021-2025
Hospital Universitario de Canarias
2022-2023
Fungi of the family Botryosphaeriaceae are considered responsible for various symptoms in avocado such as dieback, external necrosis branches and inflorescences, cankers on trunks, or stem-end rot fruits. In recent years, these problems becoming more frequent orchards Canary Islands (Spain). This work includes characterization fungal species involved diseases, which were isolated from crops Tenerife Island between 2018 2022. A total 158 vegetal samples collected, 297 isolates...
The Canary Islands, a region with high asthma prevalence, are frequently exposed to Saharan Dust Intrusions (SDIs), as wide range of countries in Europe. Alpha-1 antitrypsin (SERPINA1 gene) regulates the airway's inflammatory response. This study analyzed combined effect SDI exposure and SERPINA1 variants on bacterial/fungal DNA concentrations saliva pharyngeal samples from asthmatic patients. Bacterial fungal DNAs were quantified by qPCR 211 patients (GEMAS study), grouped based their daily...
Asthma is a chronic inflammatory disease of the airways. patients may experience potentially life-threatening episodic flare-ups, known as exacerbations, which significantly contribute to asthma burden. The Pi*S and Pi*Z variants SERPINA1 gene, usually involve alpha-1 antitrypsin (AAT) deficiency, had previously been associated with asthma. link between AAT deficiency might be represented by elastase/antielastase imbalance. However, their role in exacerbations remains unknown. Our objective...
El Hierro is the smallest and westernmost island of Canary Islands, whose population derives from an admixture different ancestral components that has been subjected to genetic isolation. We established "El Genome Study" characterize health status composition ~10% current island, accounting for a total 1054 participants. Detailed demographic clinical data blood sample DNA extraction were obtained each participant. Genomic genotyping was performed with Global Screening Array (Illumina). The...
Alpha-1-antitrypsin deficiency (AATD) is a heritable condition that predisposes to respiratory and hepatic complications. Screenings in East Asia human populations for the AATD alleles most commonly found among Caucasians have yielded poor outcomes. Serum alpha-1-antitrypsin (AAT) levels, AAT phenotypes, sequences of SERPINA1 gene were examined Chinese child with moderate deficit serum AAT, who had suffered several episodes liver disease, as well his first-order relatives. Results allowed...
Abstract Banana cultivars of agronomic interest have been genetically characterized using two different molecular markers. On the one hand, a panel 14 trinucleotide single sequence repeats (SSRs or microsatellites) was optimized for homogeneous PCR conditions. It tested with 50 individuals from seven cultivars, yielding 76 alleles and 5.4 ± 1.8 per locus, while presence cultivar‐exclusive allowed discrimination all cultivars. other retrotransposon‐based marker system named inter‐primer...
Alpha‐1 antitrypsin deficiency (AATD) is a genetic disorder caused by specific variants in the SERPINA1 gene, which encodes AAT. The most common disease‐associated are Pi ∗ S and Z alleles, cause moderate severe AATD, respectively. Recent studies have reported presence of possible regulator SERPINA gene cluster expression (LOC126862032), suggested to act as BRD4‐Independent Enhancer ( ‐BIE). This study aimed at characterizing ‐BIE locus assessing associations with AATD‐related alleles. For...
Persea americana (avocado) represents one of the most demanded food products worldwide, with an important impact in several agronomy-based economies. The avocado is salt-sensitive and valuable crops. It therefore necessary to use salt-tolerant varieties, such as West Indian, for cultivation locations soil salinity problems, Canary Islands. Therefore, characterization cultivars demand, well development molecular tools able easily identify main horticultural races. In present work,...
Abstract Rumex lunaria is an endemic shrub of the Canary Islands, which colonizing Timanfaya National Park (TNP) in Lanzarote. Whether arrival R. to Lanzarote has been natural or by human intervention still a matter debate. To address this question, 100 specimens were collected from seven main and genetic analysis four chloroplast DNA loci performed, covering total length 4809 nucleotide positions. Multiple alignments revealed 49 substitutions, define 30 different haplotypes. Island-specific...