A5101832660- Glioma Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Meningioma and schwannoma management
- Medical Image Segmentation Techniques
- Advancements in Semiconductor Devices and Circuit Design
- Semiconductor materials and devices
- Medical Imaging and Analysis
- Functional Brain Connectivity Studies
- 2D Materials and Applications
- Ferroelectric and Negative Capacitance Devices
- Anatomy and Medical Technology
- TGF-β signaling in diseases
- Medical Imaging Techniques and Applications
- MRI in cancer diagnosis
- Peripheral Nerve Disorders
- Neurobiology of Language and Bilingualism
- Chemokine receptors and signaling
- Ferroelectric and Piezoelectric Materials
- Head and Neck Surgical Oncology
- Radiomics and Machine Learning in Medical Imaging
- Neural dynamics and brain function
- Atomic and Subatomic Physics Research
- Neurofibromatosis and Schwannoma Cases
- Integrated Circuits and Semiconductor Failure Analysis
Fudan University
2010-2024
Civil Aviation Flight University of China
2024
Huashan Hospital
2010-2024
Suzhou University of Science and Technology
2021-2023
Shanghai Center for Brain Science and Brain-Inspired Technology
2023
Shanghai Medical College of Fudan University
2014-2017
State Key Laboratory of ASIC and System
2010-2013
Shanghai Fudan Microelectronics (China)
2011-2012
William & Mary
2010
Williams (United States)
2010
One of the major problems p-i-n tunneling field-effect transistor (TFET) is reliability due to strong electric field near junction. In this paper, using technology computer-aided design simulation, we show that insertion a thin n-layer into junction TFET (p-n-i-n TFET) not only enhances its drive current, as has been previously reported, but also improves reliability. As compared with conventional TFET, demonstrate following properties p-n-i-n TFET: 1) The normal component reduced, and...
Glioma surgery in eloquent areas remains a challenge because of the risk postoperative motor deficits.To prospectively evaluate efficiency using combination diffusion tensor imaging (DTI) tractography functional neuronavigation and direct subcortical stimulation (DsCS) to yield maximally safe resection cerebral glioma areas.A prospective cohort study was conducted 58 subjects with an initial diagnosis primary within or adjacent pyramidal tract (PT). The white matter beneath cavity stimulated...
The marginal delineation of gliomas cannot be defined by conventional imaging due to their infiltrative growth pattern. Here we investigate the relationship between changes in glioma metabolism proton magnetic resonance spectroscopic ((1)H-MRSI) and histopathological findings order determine an optimal threshold value choline/N-acetyl-aspartate (Cho/NAA) that can used define extent spread.Eighteen patients with different grades were examined using (1)H-MRSI. Needle biopsies performed under...
Wu, Jin-Song MD, PhD*; Gong, Xiu MD‡; Song, Yan-Yan PhD§; Zhuang, Dong-Xiao Yao, Cheng-Jun Qiu, Tian-Ming MD*; Lu, Jun-Feng Zhang, Jie Zhu, Wei PhD¶; Mao, Ying Zhou, Liang-Fu MD¶ Author Information
OBJECTIVE To evaluate the applicability of low-field intraoperative magnetic resonance imaging (iMRI) during transsphenoidal surgery pituitary macroadenomas. METHODS Fifty-five surgeries were performed for macroadenomas (modified Hardy's Grade II–IV) resections. All surgical processes guided by real-time updated contrast T1-weighted coronal and sagittal images, which acquired with 0.15 Tesla PoleStar N20 iMRI (Medtronic Navigation, Louisville, CO). The definitive benefits as well major...
Abstract Patients with frontal lobe gliomas often experience neurocognitive dysfunctions before surgery, which affects the default mode network (DMN) to different degrees. This study quantitatively analyzed this effect from perspective of cerebral hemispheric functional connectivity (FC). We collected resting-state fMRI data 20 glioma patients treatment and healthy controls. All controls were right-handed. After pre-processing images, FC maps built seed defined in left or right posterior...
OBJECTIVE This study aimed to assess the clinical efficiency of combined awake craniotomy with 3-T intraoperative MRI (iMRI)–guided resection gliomas adjacent eloquent cortex performed at a single center. It also sought explore contribution iMRI surgeons' learning process maximal safe gliomas. METHODS All patients who underwent an and for area glioma during 53 months between January 2011 June 2015 were included. The cases analyzed short- long-term neurological outcome, progression-free...
Abstract Chinese processing has been suggested involving distinct brain areas from English. However, current functional localization studies on speech use mostly “indirect” techniques such as magnetic resonance imaging and electroencephalography, lacking direct evidence by means of electrocortical recording. In this study, awake craniotomies in 66 Chinese‐speaking glioma patients provide a unique opportunity to directly map eloquent language areas. Intraoperative stimulation was conducted...
<h3>BACKGROUND AND PURPOSE:</h3> Resting-state functional MR imaging has been used for motor mapping in presurgical planning but never intraoperatively. This study aimed to investigate the feasibility of applying intraoperative resting-state safe resection gliomas using real-time cortex during an operation. <h3>MATERIALS METHODS:</h3> Using interventional imaging, we conducted preoperative and intrinsic connectivity analyses 30 patients with brain tumors. Factors that may influence quality,...
As a promising noninvasive imaging technique, functional MRI (fMRI) has been extensively adopted as localization procedure for surgical planning. However, the information provided by preoperative fMRI (pre-fMRI) is hampered brain deformation that secondary to procedures. Therefore, intraoperative (i-fMRI) becomes potential alternative can compensate shifts updating during craniotomy. previous i-fMRI studies required patients be under general anesthesia, preventing wider application of such...
The aim of this study was to assess the diagnostic accuracy diffusion kurtosis magnetic resonance imaging parameters for differentiating high-grade gliomas (HGGs) from primary central nervous system lymphomas (PCNSLs).Diffusion parameters, including fractional anisotropy (FA), mean diffusivity (MD), axial (λ// ), radial (λ⊥ ); and (MK), (K// (K⊥ were normalized contralateral normal-appearing white matter (NAWMc) decrease inter-individual inter-regional changes across entire brain, then...
<h3>BACKGROUND AND PURPOSE:</h3> Intraoperative brain deformation is an important factor compromising the accuracy of image-guided neurosurgery. The purpose this study was to elucidate role a model-updated image in compensation intraoperative shift. <h3>MATERIALS METHODS:</h3> An FE linear elastic model built and evaluated 11 patients with craniotomies. To build model, we provided novel model-guided segmentation algorithm. After craniotomy, sparse data (the deformed cortical surface) were...
The reliability performance of In <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</i> Ga <sub xmlns:xlink="http://www.w3.org/1999/xlink">1-</sub> As n-type metal-oxide-semiconductor field-effect transistors with Al xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> gate dielectric under positive-bias temperature instability stress is investigated systematically. A model stress-induced border...
As part of the ITK v4 project efforts, we have developed filters for physics-based non-rigid registration (PBNRR), which satisfies following requirements: account tissue properties in registration, improve accuracy compared to rigid and reduce execution time using GPU multi-core accelerators. The implementation has three main components: (1) Feature Point Selection, (2) Block Matching (mapped both processors), (3) a Robust Finite Element Solver. use accelerators provides substantial...
This study aimed at an analysis of expression epidermal-type and brain-type fatty acid-binding proteins (E-FABP B-FABP, also called FABP5 FABP7, respectively) in adult hippocampus their potential value as neuroprotective factors after ischemic brain damage monkey model. The immunostaining Western blotting results show that was mainly expressed neurons, whereas FABP7 primarily astrocytes progenitors the subgranular zone (SGZ). Interestingly, neurons increased cornu Ammonis 1 (CA1) remains...
OBJECTIVE Jugular foramen schwannomas (JFSs) are rarely seen, benign tumors with slow growth. Today, management options for JFSs include observation, surgery, and radiation. However, the optimal treatment strategy remains controversial. Stereotactic radiosurgery serves as a minimally invasive alternative or adjuvant therapeutic regimen of microsurgery. Gamma Knife is suitable patients JFS who have small- medium-sized normal cranial nerve (CN) function. Hypofractionated stereotactic...