A5020952052- Burn Injury Management and Outcomes
- Wound Healing and Treatments
- Injury Epidemiology and Prevention
- Trauma and Emergency Care Studies
- Acute Kidney Injury Research
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Disaster Response and Management
- Thermal Regulation in Medicine
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Pressure Ulcer Prevention and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Corneal Surgery and Treatments
- Nosocomial Infections in ICU
- Respiratory Support and Mechanisms
- Antibiotic Resistance in Bacteria
- Reconstructive Surgery and Microvascular Techniques
- Silk-based biomaterials and applications
- Climate Change and Health Impacts
- Dermatologic Treatments and Research
- Medical Imaging and Pathology Studies
- Maternal and fetal healthcare
- Laser Applications in Dentistry and Medicine
- Neonatal Health and Biochemistry
- Skin Protection and Aging
Hallym University
2012-2024
Hallym University Medical Center
2013-2024
Hangang Sacred Heart Hospital
2014-2024
Marymount University
2017-2018
Sacred Heart Hospital
2012
Jun Hur, M.D., Hyeong Tae Yang, Wook Chun, Jong-Hyun Kim, Seon-Hee Shin, Hee Jung Kang, and Hyun Soo M.D.. Ann Lab Med 2015;35:105-10. https://doi.org/10.3343/alm.2015.35.1.105
Abstract Introduction The reported mortality rates range from 28% to 100% in burn patients who develop acute kidney injury (AKI) and 50% among such treated with renal replacement therapy. Recently, the serum cystatin C plasma urine neutrophil gelatinase-associated lipocalin (NGAL) levels have been introduced as early biomarkers for AKI; of these are known increase 24 48 hours before creatinine increase. In this study, we aimed estimate diagnostic utility NGAL post-burn period predicting AKI...
Abstract Sepsis and septic shock are prevalent life-threatening complications in burn patients. Despite their severity, existing diagnostic methods limited. This study aims to evaluate the efficacy of Complete Blood Count (CBC) CBC ratio markers diagnosing sepsis shock, predicting mortality among A cohort 2757 patients was examined ascertain correlation between various parameters, ratios, incidence related mortality. Key analyzed included Red Cell Distribution Width (RDW), Mean Platelet...
Abstract This study aims to evaluate the utility of complete blood count (CBC) markers, in conjunction with acute kidney injury network (AKIN) criteria, for early detection, severity assessment, and prediction mortality outcomes (AKI) burn patients. The research seeks fill existing gaps knowledge validate cost-effectiveness using CBC as a routine diagnostic tool better management AKI. was conducted at Hangang Sacred Heart Hospital. We performed large-scale retrospective analysis 2758 adult...
To develop a population pharmacokinetic model of meropenem in burn patients and to explore the appropriateness current dosage regimens. Fifty-nine with burns ranging from 3% 97% total body surface area treated were analysed. The parameters 59 estimated, concentrations simulated by using mixed effect method (NONMEM, ver. 6.2). final was two-compartment first-order elimination where creatinine clearance (CLCR) oedema contributed. mean (L/h) = 4.45 + 10.5 × CLCR (mL/min)/138, V1 (central...
Inhalation injury is known to be an important factor in predicting mortality burns patients. However, the diagnosis complicated by heterogeneous presentation and inability determine severity of inhalation injury. The purpose this study was identify clinical features that affect values could predict outcome more precisely patients with This retrospective observational included 676 who were over 18 years age hospitalized Burns Intensive Care Unit between January 2012 December 2015. We analyzed...
This prospective observational study was performed to analyze the clinical outcomes of patients with massive burns treated using cultured epithelial autografts (CEAs) and determine association this treatment survival outcomes. During 2006-2013, total 177 massive-burns subjects (96 subjects) or without (81 CEAs. Data were analyzed independent t test chi-square test. Multivariate logistic regression, Kaplan-Meier survival, Cox regression analyses evaluate factors that influenced mortality....
Objectives: We evaluated the ability of new sepsis (S3) criteria (compared with previous definitions [S1] and burn criteria) to accurately determine mortality in severe burns patients sepsis. Design: This was retrospective cohort study. Setting: The Burn ICU Center, Hangang Sacred Heart Hospital, Hallym University, Seoul, Korea. Patients: A total 1,185 adult (mean age, 49.1 yr) were admitted between January 2009 December 2015. Interventions: enrolled present study then re-evaluated based on...
Background : The purpose of this study is to clarify the clinical significance serum transthyretin (TTR) in massively burned patients nutrition support and severity. Methods A retrospective was performed with 204 admitted Hangang Sacred Heart Hospital's Burn Center September 2010‐September 2012 burn wounds > 20% total body surface area (TBSA) burned. Serum TTR, C‐reactive protein (CRP), lactic acid, an NST index (calculated by dividing real caloric intake estimated need for 7 days) were...
Purpose The purpose of this study was to develop a new prediction model reflect the risk mortality and severity disease evaluate ability developed predict among adult burn patients. Methods This included 2009 patients aged more than 18 years who were admitted intensive care unit (ICU) within 24 hours after burn. We divided into two groups; those from January 2007 December 2013 in derivation group 2014 September 2017 validation group. Shrinkage methods with 10-folds cross-validation performed...
The pharmacokinetic (PK) property of fluconazole might be significantly altered in major burn patients by medical interventions and physiologic changes. In this study, our aims were to investigate PK using a population approach recommend the optimal regimen based upon predicted therapeutic outcome. At steady state, blood samples for analysis obtained from 60 receiving between 100 ~400 mg daily. A mixed-effect modeling was performed outcome antifungal therapy 10,000 virtual NONMEM (version...
We observed that serum transthyretin (TTR) levels consistently remain low when patients' general conditions are poor, despite adequate nutritional support. conducted this study to analyze the changes of TTR over time from injury in massively-burned patients and verify validity prediction by clinical outcomes, which assessed via early postburn period.From January 2005 December 2010, samples 471 burn (mean % total body surface area [TBSA] burned, 51% ± 20%) were analyzed with frames...
This study was aimed at evaluating the effectiveness of serum cystatin C and microalbuminuria as diagnostic markers for acute kidney injury (AKI) in major burn patients.Major adult patients admitted to intensive care unit within 24 h from onset were enrolled. Serum (albumin-creatinine ratio, ACR) obtained postburn days 1, 3, 7, 14, 21 28. The divided into two groups AKI group nonacute group.A total 97 enrolled this study. Acute diagnosed 40 (41.2%) day 17.3 ± 7.9. area under curve receiver...
Purpose Sepsis-3 is a life-threatening organ dysfunction caused by dysregulated host responses to infection; and defined using the criteria, introduced in 2016, however, criteria need be validated specific clinical fields. We investigated mortality prediction compared diagnostic performance of quick Sequential Organ Failure Assessment (qSOFA), systemic inflammatory response syndrome (SIRS), burn-specific SIRS (bSIRS) burn patients. Methods This single-center retrospective cohort study...
Abstract Background Sepsis is a potentially life-threatening condition that occurs when the body’s response to infection leads widespread inflammation and tissue damage. Negative cultures can make it difficult for clinicians diagnosis may raise questions about validity of definition sepsis. In addition, clinical distinctions between burn patients with blood culture-positive -negative sepsis are also poorly understood. Therefore, this study aimed examine differences in order improve...