A5062882893- Reproductive System and Pregnancy
- Cancer-related molecular mechanisms research
- RNA Research and Splicing
- Advanced Glycation End Products research
- Adipokines, Inflammation, and Metabolic Diseases
- Endometriosis Research and Treatment
- Retinoids in leukemia and cellular processes
- Cancer-related gene regulation
- Aldose Reductase and Taurine
- Protein Hydrolysis and Bioactive Peptides
- Cancer, Hypoxia, and Metabolism
- Biotin and Related Studies
- Liver Disease Diagnosis and Treatment
- Protein Degradation and Inhibitors
- Reproductive Biology and Fertility
- Aquatic life and conservation
- Extracellular vesicles in disease
- Signaling Pathways in Disease
- Public Health and Nutrition
- Ovarian function and disorders
- Pelvic floor disorders treatments
- Nuclear Receptors and Signaling
- Hepatitis B Virus Studies
Zhongda Hospital Southeast University
2022-2023
Guangzhou University
2023
Nanchang University
2020-2022
Jiangxi Maternal and Child Health Hospital
2022
Oocyte maturation disorder and decreased quality are the main causes of infertility in women, granulosa cells (GCs) provide only microenvironment for oocyte through autocrine paracrine signaling by steroid hormones growth factors. However, chronic inflammation oxidative stress caused ovarian hypoxia largest contributors to aging GC dysfunction. Therefore, amelioration is expected be a pivotal method improve function quality. In this study, we detected protective effect chitosan...
Non-alcoholic fatty liver disease (NAFLD) is a public health challenge and an increasing cause of chronic worldwide. However, the underlying molecular mechanism remains unclear. The aim this study was to determine precise role serpina3c in process NAFLD. Male Apoe-/- /serpina3c-/- double knockout (DKO) mice were fed high-fat diet (HFD) for 12 weeks. Several markers steatosis inflammation evaluated. In vitro cell models induced by palmitic acid (PA) treatment used evaluate beneficial effect...
Chronic low-grade inflammation and ovarian germline stem cells (OGSCs) aging are important reasons for the decline of reserve function, resulting in infertility. Regulation chronic is expected to promote proliferation differentiation OGSCs, which will become a key means maintaining remodeling function. Our previous study demonstrated that Chitosan Oligosaccharides (Cos) promoted OGSCs remodelled function through improving secretion immune related factors,but mechanism remains unclear, role...
Objective: Studies have found that high expression of human Kallistatin (HKS) in adipose tissue can improve obesity and its associated comorbidities, but the underlying mechanism specific regulation is unclear. Methods: An model was built by injecting 8-week-old C57BL/6 mice (n = 6 per group) with Ad.Null Ad.HKS adenovirus into epididymal fed a high-fat diet (HFD). Insulin resistance-related proteins, AKT IRS1, were detected liver, subcutaneous fat, skeletal muscle western blotting after one...
Skin wound caused by burns, disease, etc., is a substantial healthcare issue, it may result in infection and chronic state, long-term incidence even death. A highly effective viable therapy involved healing, this will present the more significant exploration. Marine bioactive peptides are currently being utilized due to their beneficial biological properties, which encompass anti-inflammatory, antioxidant, antimicrobial, anti-aging, antitumor activities, antihypertensive. These offer...