Zheng-Wei Zhu

ORCID: 0000-0003-1432-1115
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Research Areas
  • Advanced Fiber Optic Sensors
  • Geotechnical Engineering and Underground Structures
  • Acupuncture Treatment Research Studies
  • Photonic and Optical Devices
  • Railway Engineering and Dynamics
  • Structural Health Monitoring Techniques
  • Healthcare and Venom Research
  • ATP Synthase and ATPases Research
  • Neurological Disease Mechanisms and Treatments
  • High Altitude and Hypoxia
  • Tissue Engineering and Regenerative Medicine
  • Traditional Chinese Medicine Studies
  • Alzheimer's disease research and treatments
  • Neuroendocrine regulation and behavior
  • Mitochondrial Function and Pathology
  • Cardiac Ischemia and Reperfusion
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Stroke Rehabilitation and Recovery
  • Soil Mechanics and Vehicle Dynamics
  • Inflammatory mediators and NSAID effects
  • Stress Responses and Cortisol
  • Advanced Photonic Communication Systems
  • Cardiac Fibrosis and Remodeling
  • Ultrasound and Hyperthermia Applications
  • Congenital heart defects research

Chongqing Medical University
2018-2023

First People's Hospital of Chongqing
2022

Chongqing University
2010-2021

Depression is a complex clinical disorder associated with poor outcomes. Electroacupuncture (EA) has been demonstrated to have an important role in both and pre-clinical depression investigations. Evidence suggested that the P2X7 receptor (P2X7R), NLRP3, IL-1β play depressive disorder. Our study aimed at exploring of EA alleviating depression-like behaviors rats. We therefore investigated effects on prefrontal cortex liver rats subjected chronic unpredictable mild stress (CUMS) through...

10.3390/brainsci13030436 article EN cc-by Brain Sciences 2023-03-03

To observe the effect of electroacupuncture (EA) on expression apolipoprotein E (ApoE) and related proteins inflammation anti-oxidative stress in spinal cord mice with injury (SCI), so as to explore its mechanisms underlying function repair.Thirty-six female C57BL/6 were equally randomized into 3 groups: sham operation, model EA. The SCI was established by clamping for 25 s a serrefine after laminectomy 1st lumbar vertebra (L1). EA (1.5 Hz/7.5 Hz, 1.0 mA) applied bila-teral "Zusanli" (ST36)...

10.13702/j.1000-0607.190101 article EN PubMed 2019-11-25

OBJECTIVE To observe the effect of electroacupuncture(EA) on proangiogenesis process and protein turn-over in a mouse model sarcopenia, so as to explore its potential molecular mechanism anti-aging. METHODS Fourteen 30-week-old male SAMP8 mice were randomly divided into group (n=7) an EA (n=7). Seven anti-rapidly aging SAMR1 same age used control (1 mA, 4 Hz) was applied bilateral Zusanli(ST36) Yanglingquan(GB34) for 20 minutes each time once day, 6 times week weeks. The exhausted running...

10.13702/j.1000-0607.200081 article EN Acupuncture Research 2020-12-25

To explore the effect of electroacupuncture (EA) on expression synovial AMP-activated protein kinase (AMPK) α, arginase-1 mRNA, nitric oxide synthase 2 (NOS 2) NOD-like receptor 3 (NLRP 3) and interleukin-1 β (IL-1 β) mRNA in acute gouty arthritis (AGA) rats, so as to its mechanisms underlying improvement AGA via M 1/M macrophage polarization.Male Wistar rats were randomly divided into normal control, model, medication (colchicine) EA groups (n=15 each group). The model was established by...

10.13702/j.1000-0607.180498 article EN PubMed 2018-12-25

To investigate the effect of electroacupuncture (EA) combined with Donepezil on learning-memory ability and gene expression β-amyloid (Aβ) clearance-related factors in hippocampus senescence-accelerated mouse prone 8 (SAMP8) mice, so as to explore their synthetic improving dementia Alzheimer's disease (AD)..Male SAMP8 mice (30-week-old) were randomly divided into model, medication EA+medication groups (n=6 each group), other 6 senescence-resistant 1 (SAMR1) used control group. Mice group...

10.13702/j.1000-0607.190081 article EN PubMed 2020-04-25

To observe the effect of electroacupuncture (EA) on physical strength and expression levels hepatic AMP-activated protein kinase (AMPK), mammalian target rapamycin (mTOR), unc-51 like autophagy activating 1 (ULK1) proteins Atg5, Atg7, Atg13, Beclin1 ULK1 mRNAs in aging (senescence accelerated mouse/prone 8, SAMP8)mice, so as to exp lore its mechanism underlying delaying by AMPK/mTOR/ULK1 signaling pathway.Twenty-four male SAMP8 mice were randomly divided into model group, (autophagy inducer)...

10.13702/j.1000-0607.201244 article EN PubMed 2022-01-25

To investigate the effect of electroacupuncture (EA) on muscular atrophy and expression microRNAs (Mir-1, Mir-133a, Mir-133b) some proliferation-related factors muscle satellite cells as histone deacetylase4 (HDAC4) paired box transcription factor Pax7 (Pax7) in skeletal rats.Twenty-four male SD rats were randomly equally divided into sham operation, model EA groups. The was established by transection right sciatic nerve. (2 Hz, 1 mA) applied to "Zusanli"(ST36) "Huantiao"(GB30) for 10 min,...

10.13702/j.1000-0607.180721 article EN PubMed 2019-09-19
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