A5033918631- Acupuncture Treatment Research Studies
- Spinal Cord Injury Research
- Healthcare and Venom Research
- Traditional Chinese Medicine Studies
- Myofascial pain diagnosis and treatment
- Medical Research and Treatments
- Autophagy in Disease and Therapy
- Neonatal and fetal brain pathology
- Spinal Dysraphism and Malformations
- Stroke Rehabilitation and Recovery
- Nerve injury and regeneration
- Cerebral Palsy and Movement Disorders
- Medicinal Plants and Bioactive Compounds
- Educational Reforms and Innovations
- Neuroscience and Neuropharmacology Research
- Exercise and Physiological Responses
- Mitochondrial Function and Pathology
- Gastrointestinal motility and disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Alzheimer's disease research and treatments
- Nerve Injury and Rehabilitation
- Intracerebral and Subarachnoid Hemorrhage Research
- Ion Transport and Channel Regulation
- Educational Technology and Pedagogy
Chongqing Medical University
2015-2025
First People's Hospital of Chongqing
2023
Shanghai Micro Satellite Engineering Center
2021
Stanford University
2018-2020
Jiangnan University
2018
Fujian Agriculture and Forestry University
2018
Chang Hua Hospital
2007
Guangxi Normal University
2007
Chengdu University
2005
To observe the effect of electroacupuncture (EA) on neuroinflammatory response and glial scar formation Via regulating expression neutrophil extracellular traps (NETs) in mice with spinal cord injury (SCI). Sixty female C57BL/6 were randomized into sham operation, model, EA, DNase1 EA+DNase1 groups, 12 each group. The SCI model was established by clamping a serrefine after laminectomy at 11th thoracic vertebra (T11). EA (1.5 Hz/7.5 Hz, 1 mA) applied to bilateral "Jiaji" (EX-B2, T10, T12) for...
Summary Background Demyelination is one of the most important pathological factors spinal cord injury. Oligodendrocyte apoptosis involved in triggering demyelination. However, fewer reports on changes and mechanism demyelination have been presented from compressed injury ( CSCI ). The relative effect oligodendrocyte ‐induced remain unclear. Aims In this study, a custom‐designed model was used to determine whether or not occur after CSCI. axonal myelinated fibers were investigated by osmic...
ABSTRACT Curcumin is a natural product with several anti‐Alzheimer's disease (AD) neuroprotective properties. This study aimed to investigate the effects of curcumin on memory deficits, lactate content, and monocarboxylate transporter 2 (MCT2) in APP/PS1 mouse model AD. transgenic mice wild‐type (WT) C57BL/6J were used present study. Spatial learning was detected using Morris water‐maze test. Cerebral cortex hippocampus contents assay. MCT2 expression cerebral examined by...
Depression is a complex clinical disorder associated with poor outcomes. Electroacupuncture (EA) has been demonstrated to have an important role in both and pre-clinical depression investigations. Evidence suggested that the P2X7 receptor (P2X7R), NLRP3, IL-1β play depressive disorder. Our study aimed at exploring of EA alleviating depression-like behaviors rats. We therefore investigated effects on prefrontal cortex liver rats subjected chronic unpredictable mild stress (CUMS) through...
Abstract Introduction Electroacupuncture protects neurons and myelinated axons after spinal cord injury by mitigating the inflammatory response oxidative stress, but how it exerts these effects is unclear. Methods results Spinal was induced in C57BL/6 wild‐type apolipoprotein E (ApoE) knockout ( ApoE –/– ) mice, followed electroacupuncture or mimetic peptide COG112 treatment. Mice with suffered loss of hindlimb motor function through detections Basso mouse scale, histology, transmission...
Brain edema formation following intracerebral hemorrhage (ICH) appears to be related with aquaporin-4 (AQP4), which is critically involved in brain volume homeostasis and water balance. Despite its importance, the regulation of AQP4 expression transmembrane movements still remains rudimentary. Many studies suggest that internalization several membrane-bound proteins, including AQP4, may occur or without lysosomal degradation. Previously, we investigated retinal ischemic-reperfusion model....
Abstract Astrocytic necroptosis plays an essential role in the progression and regression of neurological disorders, which contributes to neuroinflammation disrupts neuronal regeneration remyelination severed axons. Electroacupuncture (EA), effective therapeutic efficacy against spinal cord injury (SCI), has been proved reduce cell apoptosis, inhibit inflammation, prompt neural stem cells proliferation differentiations. However, there have no reports on whether EA regulate astrocytic SCI...
To observe the effect of electroacupuncture (EA) on expression apolipoprotein E (ApoE) and related proteins inflammation anti-oxidative stress in spinal cord mice with injury (SCI), so as to explore its mechanisms underlying function repair.Thirty-six female C57BL/6 were equally randomized into 3 groups: sham operation, model EA. The SCI was established by clamping for 25 s a serrefine after laminectomy 1st lumbar vertebra (L1). EA (1.5 Hz/7.5 Hz, 1.0 mA) applied bila-teral "Zusanli" (ST36)...
Abstract Axonal impairment and demyelination after compressed spinal cord injury lead to serious neurological dysfunction. Increasing studies have suggested that Schwann cells (SCs) transplantation is a reliable, effective, promising method for treating injury. However, single SCs insufficient promote the full recovery of function. Additional approaches are required support as treatment In study, we investigated whether combination electroacupuncture (EA) was reliable intervention We found...
In this paper, the electrochemiluminescence (ECL) behavior of luminol/H2 O2 system in presence bromhexine hydrochloride (BrH) was investigated. It found that ECL intensity on a platinum electrode could be intensely quenched by BrH owing to scavenging superoxide radical ability BrH, and therefore sensitive determination possible. Under optimal conditions, linear concentration wide range 0.08 500 μM, with detection limit 0.02 μM (signal-to-noise ratio (S/N) = 3). This method possessed merits...
Abstract Background Functional dyspepsia (FD) is one of the most common functional gastrointestinal disorders, with a high prevalence and significant influence on quality life (QoL). Either acupuncture or moxibustion effective for dyspepsia, which confirmed by both ancient documents modern research. However, therapeutic advantage underlying mechanism between FD remain unclear. Methods This randomized controlled fMRI trial aims to (i) evaluate advantages treatment FD, (ii) investigate...
Insulin resistance (IR) is the impaired insulin response that causes decreased glucose tolerance. Electrical stimulation (ES) can improve sensitivity in skeletal muscle. However, underlying molecular mechanisms remain to be elucidated. In present study, effect of ES and diet therapy on IR role mammalian target rapamycin (mTOR) pathway improvement by were investigated. A total 70 Sprague‑Dawley male rats divided into five groups: Normal (n=10), control (n=15), (n=15) + groups. An rat model...
To explore the possible biological mechanism of skeletal muscle contusion repair through researching changes in expression autophagy-related genes and proteins SD rats with acute contusion.Six were randomly selected as control group from 30 male rats, model established remaining 24 self-made hitter, then divided into 4 groups (3 d, 5 7 14 d groups, n=6). On 3rd, 5th, 7th 14th day after injury, injured gastrocnemius each was harvested. The morphological ultra-microstructure injury observed by...