A5100637988- Gastric Cancer Management and Outcomes
- Land Use and Ecosystem Services
- Bladder and Urothelial Cancer Treatments
- Cancer Immunotherapy and Biomarkers
- Metastasis and carcinoma case studies
- Reproductive tract infections research
- Ovarian cancer diagnosis and treatment
- Urinary and Genital Oncology Studies
- Tryptophan and brain disorders
- Prostate Cancer Treatment and Research
- Conservation, Biodiversity, and Resource Management
- Cancer, Lipids, and Metabolism
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Urban Green Space and Health
- Sarcoma Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Autophagy in Disease and Therapy
- Endometrial and Cervical Cancer Treatments
- Estrogen and related hormone effects
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal Tumor Research and Treatment
- EFL/ESL Teaching and Learning
- Remote Sensing and Land Use
- Ferroptosis and cancer prognosis
Jinshan Hospital of Fudan University
2024-2025
Central South University
2023-2025
Shanghai Medical College of Fudan University
2024-2025
Xiangya Hospital Central South University
2023-2025
Sun Yat-sen Memorial Hospital
2020-2024
Sun Yat-sen University
2014-2024
Chinese PLA General Hospital
2024
Fujian Medical University
2021-2024
Qilu Hospital of Shandong University
2019-2024
Union Hospital
2021-2024
Understanding the coordinative relationship between urbanization and ecosystem services (ESs) has a great significance in sustainable development urban agglomeration. In this paper, InVEST model was firstly used to assess spatio-temporal evaluation of four types ESs (water yield, carbon storage, soil retention nitrogen export) Yangtze River Delta Urban Agglomerations (YRDUA) China from 2000 2020. Then comprehensive index system established multi-dimensions economy, population land analyze...
The aim of this study was to explore the microecological distribution and differences in uterus vaginal microbiome women with early embryonic arrest those normal pregnancy by high-throughput sequencing. We systematically sampled uterine microbiomes 56 pregnant women, namely, 38 patients 18 pregnancy-induced abortion. obtained colonization data 16S rRNA gene amplicon In vagina, Lactobacillus , Bacteroidetes Helicobacter exhibited significant between groups. further found that iners crispatus...
Abstract Background The objective of the current study was to investigate correlation between trajectories maternal perinatal depression (PND) spanning from early pregnancy one year postpartum and developmental delays observed in one-year-old children. Methods dataset under examination encompassed 880 women who took part a mother-child birth conducted China. Latent class growth analysis (LCGA) employed identify patterns Edinburgh Postnatal Depression Scale (EPDS) scores women, postpartum. To...
Abstract Cyclooxygenase‐2 (COX‐2) is a key molecule in the inflammatory pathway amyotrophic lateral sclerosis (ALS). Cytosolic phospholipase A (cPLA2) an important enzyme providing substrate for cyclooxygenases. We therefore examined cPLA2 expression human ALS and mutant Cu/Zn superoxide dismutase (SOD1) transgenic mice its relation to COX‐2. Immunohistochemistry real‐time RT‐PCR revealed elevated protein mRNA levels lumbar spinal cord of SOD1 mice. COX‐2 immunoreactivity was increased...
Abstract Inefficient utilization puts the productivity of cultivated land in a low development state. The key challenge for efficient is to clarify how various factors affect spatial differentiation pattern (CLP), improve food production. However, evaluating impact intensity and direction CLP on large‐scale difficulty there gap knowledge. In this study, we used net primary (NPP) calculate reveal its differentiation. Also, study examined spatio‐temporal heterogeneity determined effect...
AR signalling pathway reactivation plays a key role in the development of castration‑resistant prostate cancer (CRPC). High‑mobility group protein B1 (HMGB1) is an important factor involved occurrence and variety tumours by regulating gene transcription. In present study, association between HMGB1 (PCa) effects on androgen receptor (AR) transcription PCa cells vitro vivo were evaluated. A bioinformatics method was used to determine mRNA expression level specimens its correlation with AR....
ABSTRACT Ovarian cancer (OC) is a deadly disease and lacks precise marker for diagnosis worldwide. Our previous work has shown the overexpression of flotillin‐1 (FLOT1) in OC tissue. To improve diagnostic sensitivity accuracy, we evaluated serum level FLOT1 patients found that concentration as well CA125 was significantly increased with compared healthy control ( p < 0.01) those benign tumors 0.05). The detection rate (above upper limit cut‐off value) 77.78% 72.22%, respectively, OC,...
Abstract Background To investigate distributions of cervical lesions and factors associated with the severity in high-risk HPV (hr-HPV) positive women atypical squamous cells undetermined significance (ASC-US) cytology. Methods Clinical information 250,000 who underwent cytological test was collected from January 2012 to 2019. The association between hr-HPV genotypes, viral load, ages, were analyzed hr-HPV-positive/ASC-US women. Results 3459 enrolled this study. Overall, 43.51% ASC-US had...
Abstract Irritable bowel syndrome (IBS) is a widespread gastrointestinal disorder known for its multifaceted pathogenesis and varied extraintestinal manifestations, yet implications bone muscle health are underexplored. Recent studies suggest link between IBS musculoskeletal disorders, but comprehensive understanding remains elusive, especially concerning the role of bile acids (BAs) in this context. This study aimed to elucidate potential contribution deterioration via alterations gut...
Our previous study showed that pyridoxine 5'-phosphate oxidase (PNPO) is a tissue biomarker of ovarian cancer (OC) and has prognostic implication but detailed mechanisms remain unclear. The current focused on PNPO-regulated lysosome/autophagy-mediated cellular processes the potential role PNPO in chemoresistance. We found was overexpressed OC cells factor patients. significantly promoted cell proliferation via regulation cyclin B1 phosphorylated CDK1 shortened G2M phase cycle. Overexpressed...
To reduce excessive scarring in wound healing, electrospun nanofibrous meshes, composed of haloarchaea-produced biodegradable elastomer poly(3-hydroxybutyrate- co-3-hydroxyvalerate) (PHBV), are fabricated for use as a dressing. Three PHBV polymers with different 3HV content used to prepare either solution-cast films or meshes. As increases, the crystallinity decreases and scaffolds become more elastic. The meshes exhibit greater elasticity elongation at break than films. When culture human...
Purpose: The aim of this study was to review the clinicopathologic characteristics, treatments, and outcomes patients with primary large cell neuroendocrine carcinoma bladder (LCNEC). Patients Methods: We report one patient diagnosed pure LCNEC in Sun Yat-sen Memorial Hospital. In addition, we performed a systematic literature review, April 2020, on case series bladder. treatments rare disease were analyzed. Results: A total 39 included our analysis (1 from institution 38 cases literature)....
Recent centuries have witnessed a considerable economic growth, but also been accompanied by ecological deterioration which has led to the utility decline in every hard-won material wealth. Here we proposed comprehensive framework for detecting these growth expenses, combining ecosystem services chain with economics principles. Remote sensing products, biophysical process modeling, and inferential geostatistics were comprehensively used tracing quantity quality of natural capital, total...
The development of resilient cities has become a critical global issue with respect to the stimulation sustainable economic, social, and ecological advancement. Yangtze River Delta region, which is most densely populated region in China, undergoing fastest urbanization achieving highest level economic country. Thus, it great theoretical practical significance study evolution spatiotemporal city resilience this region. For study, 41 core China from 2010 2020 was evaluated through combination...