- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Innovations in Medical Education
- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Nosocomial Infections in ICU
- Evaluation of Teaching Practices
- Health Sciences Research and Education
- Antibiotics Pharmacokinetics and Efficacy
- Cancer therapeutics and mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Pharmaceutical Practices and Patient Outcomes
- Appendicitis Diagnosis and Management
- Sepsis Diagnosis and Treatment
- Evaluation and Performance Assessment
- Synthesis and Biological Evaluation
- Clostridium difficile and Clostridium perfringens research
- Bacterial Identification and Susceptibility Testing
- Helicobacter pylori-related gastroenterology studies
- Dialysis and Renal Disease Management
- Neutropenia and Cancer Infections
- Respiratory Support and Mechanisms
- Antibiotic Use and Resistance
- Polyomavirus and related diseases
Roseman University of Health Sciences
2017-2022
Valley Hospital Medical Center
2019-2020
California Northstate University
2014-2015
Banner - University Medical Center Tucson
2012-2013
University of Arizona
2009-2013
Arizona Oncology
2013
University of Missouri
2009
Multidrug-resistant Acinetobacter baumannii remains challenging to treat. Although eravacycline has in vitro activity against this pathogen, there are no studies evaluating outcomes.To assess the efficacy of compared with best previously available therapy adults difficult-to-treat resistant (DTR) A. pneumonia.This was a retrospective study hospitalized for pneumonia DTR baumannii. Patients receiving were those therapy. The primary outcome 30-day in-hospital mortality. Secondary outcomes...
Leinamycin is a structurally novel Streptomyces-derived natural product that displays very potent activity against various human cancer cell lines (IC50 values in the low nanomolar range). Previous vitro biochemical studies have revealed leinamycin alkylates DNA, generates apurinic (AP) sites and reactive oxygen species (ROS), causes DNA strand breaks. However, it not clear whether these events occur inside cells. In present study, we determined endogenous amount of AP breaks genomic...
The response of ICU patients to continuously infused ketamine when it is used for analgesia and/or sedation remains poorly established.To describe continuous infusion (CI) use in critically ill patients, including indications, dose and duration, adverse effects, patient outcomes, time goal pain/sedation score range, exposure analgesics/sedatives, delirium.Multicenter, retrospective, observational study from twenty-five diverse institutions the United States. Patients receiving CI between...
<b>Objective.</b> To assess the impact of a debate exercise on self-reported evidence student learning in literature evaluation, evidence-based decision making, and oral presentation. <b>Methods.</b> Third-year pharmacy students required infectious disease therapeutics course participated modified that included reading assignment readiness assessment tests consistent with team-based (TBL) pedagogy. Peer faculty was accomplished standardized rubric. A pre- post-debate survey used to...
A scoring system for identifying patients at high or low risk recurrent Clostridium difficile-associated diarrhea (CDAD) is described.A retrospective cohort study was performed using data on adults with CDAD admitted to a 3-hospital from 2009 2014. The primary endpoint the rate of within 60 days clinical cure CDAD. Risk factors recurrence were identified, and prediction tool developed multivariate logistic regression.The in (n = 340) 92.3%; 60-day 16.9%. Five significantly associated risk:...
Objective. To determine how changes to the student evaluation of teaching (SET) survey instrument and process at a college pharmacy contributed improved response rates understand could be further refined. Methods. Pharmacy students from class 2018 who had participated in both old new SET were recruited participate one four focus group interviews. An inductive approach was used for data collection analysis. A guide created based on two major domains: comparing between form, determining...
<b>Objective.</b> To describe the landscape of teaching and learning curriculum (TLC) programs sponsored by US schools colleges pharmacy evaluate their adoption best practice recommendations. <b>Methods.</b> A 28-item electronic survey instrument was developed based on recommendations published American Association Colleges Pharmacy (AACP), Society Health-System Pharmacists (ASHP), College Clinical (ACCP) for conduct TLC programs. The electronically distributed to 137 accredited in United...
Guidelines for pneumonia recommend empiric dual antipseudomonal therapy in patients with specific risk factors. However, there is lack of consensus on when to use as the recommendations are rated weak, based low-quality evidence.The objectives this study were develop combination antibiograms assess susceptibility Pseudomonas aeruginosa (P. aeruginosa) respiratory cultures combinations antibiotics and delineate impact factors which guidelines therapy.A retrospective cohort was conducted...
This paper presents 10 key tips or recommendations for successful navigation of the promotion and tenure process. The are: know institutional expectations, develop an action plan at least two to three years in advance; identify your balance teaching, scholarship, service; synergize activities a niche; prioritize time high-impact tenure; track achievements format expected application; seek out faculty guidance on meet with mentor(s) regularly review progress; have well-written personal...
Groth, Christine1; Droege, Chris2; Connor, Kathryn3; Kaukeinen, Kimberly4; Acquisto, Nicole5; Chui, Sai Ho6; Cucci, Michaelia7; Dixit, Deepali8; Flannery, Alexander9; Gustafson, Kyle10; Glass, Nina11; Horng, Helen12; Heavner, Mojdeh13; Kinney, Justin14; Kruer, Rachel15; Peppard, William16; Sarangarm, Preeyaporn17; Newsome, Andrea18; Viswesh, Velliyur19; Erstad, Brian20 Author Information
Groth, Christine1; Connor, Kathryn2; Kaukeinen, Kimberly3; Acquisto, Nicole4; Chui, Sai Ho5; Cucci, Michaelia6; Dixit, Deepali7; Droege, Chris8; Flannery, Alexander9; Gustafson, Kyle10; Glass, Nina11; Horng, Helen12; Heavner, Mojdeh13; Kinney, Justin14; Kruer, Rachel15; Peppard, William16; Sarangarm, Preeyaporn17; Newsome, Andrea18; Viswesh, Velliyur19; Erstad, Brian20 Author Information
Although there is an abundance of literature on the acute management enterocutaneous fistulas, a paucity data chronic fistulas. Their impact oral pharmacotherapy, including their effect bioavailability medications, poorly understood. This case describes 23-year-old quadriplegic male with complex history multiple abdominal surgeries presented three persistent Diazepam and furosemide were among patient's medications had sufficient to show efficacy anxiety pedal edema, respectively. Conversely,...
Groth, Christine1; Sarangarm, Preeyaporn2; Gustafson, Kyle3; Rappaport, Stephen4; Kaukeinen, Kimberly5; Connor, Kathryn4; Acquisto, Nicole6; Chui, Sai Ho4; Cucci, Michaelia7; Dixit, Deepali8; Droege, Christopher9; Flannery, Alexander10; Glass, Nina11; Horng, Helen12; Heavner, Mojdeh13; Kruer, Rachel14; Peppard, William15; Newsome, Andrea16; Viswesh, Velliyur17; Erstad, Brian18 Author Information
Background High-risk febrile neutropenia (FN), an oncologic emergency common in patients receiving myelosuppressive chemotherapy, requires prompt initiation of broad-spectrum antibacterials with current guidelines recommending meropenem 1 g intravenously (IV) every 8 hours as first-line treatment. However, alternative dosage meropenem, 500 mg IV 6 hours, has been shown to attain a similar percentage time above the minimum inhibitory concentration (%T > concentration) lower daily dose and...