A5074550649- Pharmaceutical Practices and Patient Outcomes
- Intensive Care Unit Cognitive Disorders
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Antimicrobial Resistance in Staphylococcus
- Anesthesia and Sedative Agents
- Opioid Use Disorder Treatment
- Trauma and Emergency Care Studies
- Bacterial Identification and Susceptibility Testing
- Anesthesia and Pain Management
- Pain Management and Opioid Use
- Cardiac Arrest and Resuscitation
- Liver Disease and Transplantation
- Patient Safety and Medication Errors
- Trauma Management and Diagnosis
- Antifungal resistance and susceptibility
- Clinical Nutrition and Gastroenterology
- Anesthesia and Neurotoxicity Research
- Sepsis Diagnosis and Treatment
- Facial Trauma and Fracture Management
- Drug-Induced Hepatotoxicity and Protection
- Liver Disease Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Head and Neck Surgical Oncology
- Electrolyte and hormonal disorders
Froedtert Hospital
2016-2025
Medical College of Wisconsin
2016-2025
Loyola University Chicago
2025
Lutheran Hospital
2013-2019
American Association for Thoracic Surgery
2019
Creative Commons
2018
Concordia University Wisconsin
2017
To develop evidence-based recommendations for clinicians caring adults with acute or on chronic liver failure in the ICU.The guideline panel comprised 29 members expertise aspects of care critically ill patient and/or methodology. The Society Critical Care Medicine standard operating procedures manual and conflict-of-interest policy were followed throughout. Teleconferences electronic-based discussion among panel, as well within subgroups, served an integral part development.The was divided...
BACKGROUND Rib fractures occur in up to 40% of trauma patients and are associated with increased mortality. Opiate-based pain regimens remain the cornerstone rib fracture management; however, concerns around opioids have fostered interest alternative analgesics. Ketamine is currently being used lieu opioids, but little evidence exists supporting its use within population. METHODS A prospective, randomized, double-blind placebo-controlled trial adult three or more admitted a Level I center...
Current guidelines provide weak recommendations for starting enteral nutrition (EN) in patients with septic shock (on vasopressor support). Outcomes of receiving EN on support have not been well studied. We hypothesize that early trophic mechanically ventilated is associated improved outcomes.Single-center retrospective study admitted to identify (1) no EN, (2) <600 kcal/d within 48 hours, and (3) ≥600 hours. studied included in-hospital mortality, length intensive care unit stay (LOS),...
Demonstrate the safety and efficacy of a standardized intravenous etomidate infusion protocol in normalizing cortisol levels patients with severe life-threatening hypercortisolism.A retrospective case series seven representing nine episodes hypercortisolism at two large academic medical centers was conducted. Patients were included this if they received an for treatment hypercortisolism. The administered via newly developed designed to safely reduce until more long-term or definitive...
To comprehensively classify interventions performed by emergency medicine clinical pharmacists and quantify cost avoidance generated through their accepted interventions.A multicenter, prospective, observational study was between August 2018 January 2019.Community academic hospitals in the United States.Emergency pharmacists.Recommendations classified into one of 38 intervention categories associated with avoidance.Eighty-eight at 49 centers 13,984 during 917 shifts that were on 8,602...
To develop evidence-based recommendations for clinicians caring adults with acute liver failure (ALF) or on chronic (ACLF) in the ICU.The guideline panel comprised 27 members expertise aspects of care critically ill patient methodology. We adhered to Society Critical Care Medicine standard operating procedures manual and conflict-of-interest policy. Teleconferences electronic-based discussion among panel, as well within subgroups, served an integral part development.In 2 this guideline, was...
Introduction: Clinical pharmacists bring unparalleled medication expertise, but quantifying their impact on a health system’s bottom line remains unestablished. Objective: To classify interventions by with and without board certification quantify the cost avoidance (CA) from accepted interventions. Methods: This multicenter prospective observational study, conducted between August 2018 January 2019, included certified (BPS) non-board (Non-BPS) emergency medicine (EM) intensive care unit...
BACKGROUND Opiate-based pain regimens remain the cornerstone of management following traumatic injury, but issues related to opioids have driven research into alternative analgesics. Adjunctive ketamine has been increasingly used decrease opioid use, little evidence exists support its efficacy within trauma population. METHODS A prospective, randomized, double-blind placebo-controlled trial severely injured (Injury Severity Score [ISS], ≥15) adult patients (aged 18–64 years) admitted a Level...
The optimal dose and timing of enteral nutrition (EN) in septic shock are unclear.We conducted a phase 3 single-center randomized controlled pilot trial comparing early trophic EN with "no EN" mechanically ventilated adults shock, the hypothesis that implementing protocol patients would be feasible. Patients were to or until off vasopressor for hours. primary outcome was feasibility achieving >75% consent compliance rate <10% contamination rate.One hundred thirty-one eligible enrollment, 49...
BACKGROUND Rib fractures are associated with increased mortality, particularly in the elderly. While opiate-based pain regimens remain cornerstone of rib fracture management, issues related to opioids have driven research into alternative analgesics. Adjunctive ketamine use lieu continues increase but little evidence exists support its efficacy or safety within elderly trauma population. METHODS A prospective, randomized, double-blind placebo-controlled trial patients (age, ≥65 years) three...
Acute liver failure (ALF) and acute on chronic (ACLF) are conditions frequently encountered in the ICU associated with high mortality. The purpose of these guidelines was to develop evidence-based recommendations addressing common clinical questions surrounding unique manifestations critically ill patient. Often, care must be adapted individual circumstances patient/family preferences. These meant supplement not replace an clinician’s cognitive decision-making. primary goal is aid best...
The response of ICU patients to continuously infused ketamine when it is used for analgesia and/or sedation remains poorly established.To describe continuous infusion (CI) use in critically ill patients, including indications, dose and duration, adverse effects, patient outcomes, time goal pain/sedation score range, exposure analgesics/sedatives, delirium.Multicenter, retrospective, observational study from twenty-five diverse institutions the United States. Patients receiving CI between...
Journal Article Pharmacist involvement on a rapid response team Get access Joel Feih, Pharm.D., BCCCP, BCCCP Cardiovascular Intensive Care Unit, Froedtert & the Medical College of Wisconsin, Milwaukee, WI Address correspondence to Dr. Feih (joel.feih@froedtert.com). Search for other works by this author on: Oxford Academic Google Scholar William J. Peppard, BCPS, FCCM, FCCM Surgical Michael Katz, Pharm.D American Health-System Pharmacy, Volume 74, Issue 5_Supplement_1, 1 March 2017, Pages...
Background: A fixed dose of cefazolin results in serum concentrations that decrease as body mass increases. Current national guidelines suggest a pre-operative two grams may be insufficient for patients ≥120 kg; thus three gram is recommended. These recommendations, however, are based on pharmacokinetic rather than outcome data. We evaluate the efficacy and doses measured by rate surgical site infection (SSI). Patients Methods: conducted retrospective review adult ≥100 kg who were prescribed...
Multidrug-resistant pathogens have become increasingly common in contemporary healthcare. Specific to Gram-positive pathogens, methicillin-resistant Staphylococcus aureus (MRSA) is of particular concern, as it has been associated with increased hospital length stay, higher healthcare expenditures and poorer outcomes. To date, linezolid the first only oxazolidinone approved by US FDA for treatment infections caused including MRSA. This article will serve a comprehensive review linezolid, an...
Abstract Introduction Intensive care unit (ICU) pharmacists are integral members of the interdisciplinary health team. Pharmacy staffing models vary by ICU and hospital, clinical may cover one service or multiple services. It is presently unknown how covering rounding on services relative to impacts quantity interventions made acceptance rate those interventions. Methods Exploratory analysis PHarmacist Avoidance Reductions in Medical costs CRITically ill adults (PHARM‐CRIT) study, a...
Head and neck cancer (HNC) surgery remains an important component of management but is associated with a high rate surgical site infection (SSI). We aimed to assess the safety efficacy topical mucosal antiseptic bundle in preventing SSI evaluate microbial predictors through genomic sequencing approach.This study was open-label, single-arm, single-center, phase 2 trial patients HNC undergoing aerodigestive tract resection reconstruction. Patients underwent preparation oral mucosa...