Joanna C. Dionne
A5090236255- Nosocomial Infections in ICU
- Liver Disease and Transplantation
- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Clinical Nutrition and Gastroenterology
- Liver Disease Diagnosis and Treatment
- Clostridium difficile and Clostridium perfringens research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Family and Patient Care in Intensive Care Units
- Drug-Induced Hepatotoxicity and Protection
- Organ Transplantation Techniques and Outcomes
- Enhanced Recovery After Surgery
- Blood transfusion and management
- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- Palliative Care and End-of-Life Issues
- Gastrointestinal motility and disorders
- Grief, Bereavement, and Mental Health
- Cardiac Arrest and Resuscitation
- Healthcare Decision-Making and Restraints
- Nutrition and Health in Aging
- Renal function and acid-base balance
- Healthcare Systems and Practices
- Diet and metabolism studies
McMaster University
2016-2025
Impact
2019-2025
Population Health Research Institute
2023-2024
Hamilton Health Sciences
2023-2024
Centre hospitalier universitaire de Québec
2024
University of Toronto
2022-2024
Juravinski Hospital
2023
University of Ottawa
2022-2023
Sanquin
2023
Queen's University
2022
<h3>Importance</h3> Growing interest in microbial dysbiosis during critical illness has raised questions about the therapeutic potential of microbiome modification with probiotics. Prior randomized trials this population suggest that probiotics reduce infection, particularly ventilator-associated pneumonia (VAP), although probiotic-associated infections have also been reported. <h3>Objective</h3> To evaluate effect of<i>Lactobacillus rhamnosus</i>GG on preventing VAP, additional infections,...
Whether proton-pump inhibitors are beneficial or harmful for stress ulcer prophylaxis in critically ill patients undergoing invasive ventilation is unclear.
Stress ulcer prophylaxis (SUP) is commonly prescribed in the intensive care unit. However, data from systematic reviews and conventional meta-analyses are limited by imprecision restricted to direct comparisons. We conducted a network meta-analysis of randomized clinical trials (RCTs) examine safety efficacy drugs available for SUP critically ill patients. searched MEDLINE, EMBASE, Cochrane Library Central Register Controlled Trials through April 2017 controlled that examined proton pump...
To develop evidence-based recommendations for clinicians caring adults with acute or on chronic liver failure in the ICU.The guideline panel comprised 29 members expertise aspects of care critically ill patient and/or methodology. The Society Critical Care Medicine standard operating procedures manual and conflict-of-interest policy were followed throughout. Teleconferences electronic-based discussion among panel, as well within subgroups, served an integral part development.The was divided...
To develop evidence-based clinical practice recommendations regarding transfusion practices and in bleeding critically ill adults. A taskforce involving 15 international experts 2 methodologists used the GRADE approach to guideline development. The addressed three main topics: support massively non-massively patients (transfusion ratios, blood products, point of care testing) use tranexamic acid. panel developed answered structured questions using population, intervention, comparison,...
RATIONALE: Critically ill adults can develop stress-related mucosal damage from gastrointestinal hypoperfusion and reperfusion injury, predisposing them to clinically important upper bleeding (UGIB). OBJECTIVES: The objective of this guideline was evidence-based recommendations for the prevention UGIB in ICU. DESIGN: A multiprofessional panel 18 international experts dietetics, critical care medicine, nursing, pharmacy, two methodologists developed alignment with Grading Recommendations,...
BackgroundThe goal of this systematic review was to examine the efficacy and safety proton-pump inhibitors for stress ulcer prophylaxis in critically ill patients.MethodsWe included randomized trials comparing versus placebo or no adults, performed meta-analyses, assessed certainty evidence using Grading Recommendations, Assessment, Development, Evaluations approach. To explore effect on mortality based disease severity, a subgroup analysis conducted combining within-trial data from two...
The objective of this study was to create a definition patient-important upper gastrointestinal bleeding during critical illness as an outcome for randomized trial.
Background Pandemic-related restrictions are expected to continue shape end-of-life care and impact the experiences of dying hospitalised patients their families. Objective To understand families’ loss bereavement during after death loved one amidst SARS-CoV-2 (COVID-19) pandemic. Design Qualitative descriptive study. Setting Three acute units in a Canadian tertiary hospital. Participants Family members 28 who died from March–July 2020. Main outcome measures semistructured interviews...
To develop evidence-based recommendations for clinicians caring adults with acute liver failure (ALF) or on chronic (ACLF) in the ICU.The guideline panel comprised 27 members expertise aspects of care critically ill patient methodology. We adhered to Society Critical Care Medicine standard operating procedures manual and conflict-of-interest policy. Teleconferences electronic-based discussion among panel, as well within subgroups, served an integral part development.In 2 this guideline, was...
Acute liver failure (ALF) and acute on chronic (ACLF) are conditions frequently encountered in the ICU associated with high mortality. The purpose of these guidelines was to develop evidence-based recommendations addressing common clinical questions surrounding unique manifestations critically ill patient. Often, care must be adapted individual circumstances patient/family preferences. These meant supplement not replace an clinician’s cognitive decision-making. primary goal is aid best...