- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Luminescence and Fluorescent Materials
- Diet and metabolism studies
- Wound Healing and Treatments
- Metabolomics and Mass Spectrometry Studies
- Mitochondrial Function and Pathology
Southern Medical University
2023-2024
Southern Medical University Shenzhen Hospital
2023
Abstract Infected burn wounds are characterized by persistent drug‐resistant bacterial infection coupled with an inflammatory response, impeding the wound‐healing process. In this study, intelligent nanoparticle system (CCM+TTD@ZIF‐8 NPs) was prepared using curcumin (CCM), aggregation‐induced emission luminogens (TTD), and ZIF‐8 for infection‐induced wound healing. The CCM+TTD@ZIF‐8 NPs showed multiple functions, including bacteria targeting, fluorescence imaging pH response‐guided...
Abstract Tuberculosis, a fatal infectious disease caused by Mycobacterium tuberculosis ( M.tb ), is difficult to treat with antibiotics due drug resistance and short half‐life. Phototherapy represents promising alternative in combating . Exploring an intelligent material allowing effective treatment definitely appealing, yet significantly challenging task. Herein, all‐in‐one biomimetic therapeutic nanoparticle featured aggregation‐induced second near‐infrared emission, granuloma‐targeting,...
The combination of Astragulus embranaceus (Fisch.) Bge (Huangqi) and Dioscorea opposita Thunb (Shanyao) are one the most widely accepted herb pairs in traditional Chinese medicine prescriptions for treating sarcopenia. However, mechanisms underlying these herbs anti-sarcopenia treatment not yet fully understood.To investigate potential effect pair (Ast-Dio) on sarcopenia mice that have been induced with senile type 2 diabetes mellitus, as well to explore related Rab5a/mTOR signaling pathway...