A5025956762- Carbon dioxide utilization in catalysis
- Catalysts for Methane Reforming
- Catalysis for Biomass Conversion
- Fire dynamics and safety research
- Catalytic Processes in Materials Science
- Polyoxometalates: Synthesis and Applications
- Carbon Dioxide Capture Technologies
- Neuroscience and Neuropharmacology Research
- Luminescence and Fluorescent Materials
- Fire Detection and Safety Systems
- CO2 Reduction Techniques and Catalysts
- Lightning and Electromagnetic Phenomena
- Combustion and Detonation Processes
- Connexins and lens biology
- Neurogenesis and neuroplasticity mechanisms
- Advanced Glycation End Products research
- Supercapacitor Materials and Fabrication
- Advanced biosensing and bioanalysis techniques
- Palliative Care and End-of-Life Issues
- Cancer Mechanisms and Therapy
- Zeolite Catalysis and Synthesis
- Iron and Steelmaking Processes
- Estrogen and related hormone effects
- Combustion and flame dynamics
- Chronic Kidney Disease and Diabetes
Guizhou University
2025
Inner Mongolia University
2025
Southern Medical University
2010-2024
Sun Yat-sen Memorial Hospital
2010-2024
Sun Yat-sen University
2014-2024
Anhui University of Technology
2022-2024
Fudan University
2006-2024
Tianjin University of Science and Technology
2023-2024
The First Affiliated Hospital, Sun Yat-sen University
2007-2024
Southern Medical University Shenzhen Hospital
2023
The obstruction of post-insulin receptor signaling is the main mechanism insulin-resistant diabetes. Progestin and adipoQ 3 (PAQR3), a key regulator inflammation metabolism, can negatively regulate PI3K/AKT pathway. Here, we report that gentiopicroside (GPS), bioactive secoiridoid glycoside Gentiana manshurica Kitagawa, decreased lipid synthesis increased glucose utilization in palmitic acid (PA) treated HepG2 cells. Additionally, GPS improved glycolipid metabolism streptozotocin (STZ)...
Neuregulin 1 (NRG1) is a trophic factor that acts by stimulating ErbB receptor tyrosine kinases and has been implicated in neural development synaptic plasticity. In this study, we investigated mechanisms of its suppression long-term potentiation (LTP) the hippocampus. We found NRG1 did not alter glutamatergic transmission at SC-CA1 synapses but increased GABA A receptor-mediated currents CA1 pyramidal cells via presynaptic mechanism. Inhibition receptors blocked suppressing effect on LTP...
Endogenously produced hydrogen sulfide (H2S) may have multiple functions in brain. An increasing number of studies demonstrated its anti-inflammatory effects. In the present study, we investigated effect sodium hydrosulfide (NaHS, a H2S donor) on cognitive impairment and neuroinflammatory changes induced by injections Amyloid-β1-40 (Aβ1-40), explored possible mechanisms action. We injected Aβ1-40 into hippocampus rats to mimic rat model Alzheimer’s disease (AD). Morris water maze was used...
Solid acids have received considerable attention as alternatives to traditional corrosive and hazardous homogeneous because of their advantages in practical applications, including low corrosion equipment high catalytic activity recyclability. In this work, a strong solid acid was prepared by anchoring thiol group terminated chains on layered α-zirconium phosphate (ZrP) single-layer nanosheets, followed oxidation groups form sulfonic groups. The obtained were thoroughly characterized the...
Skeletal muscle atrophy in chronic kidney disease (CKD) leads to a decline quality of life and increased risk morbidity mortality. We have obtained evidence that oxidative stress is essential the progression CKD-related atrophy. Whether Saikosaponin A D, two emerging antioxidants extracted from Bupleurum chinense DC, alleviate remains be further studied. The purpose this study was investigate effects mechanisms these components on CKD complicated with atrophy.In research, dystrophy model...
Abstract Astrocytes are key components of the niche for neural stem cells (NSCs) in adult hippocampus and play a vital role regulating NSC proliferation differentiation. However, exact molecular mechanisms by which astrocytes modulate have not been identified. Here, we identified adenosine 5′-triphosphate (ATP) as proliferative factor required astrocyte-mediated NSCs hippocampus. Our results indicate that ATP is necessary sufficient to promote vitro. The lack inositol 1,4,5-trisphosphate...
With the worldwide attention on decreasing carbon dioxide (CO2) emissions, capture and storage (CCS) is utilized to stop CO2 from escaping into atmosphere. Selecting appropriate materials crucial for establishment of a dependable secure technology infrastructure. The natural cellulose possess inherent characteristics such as eco-friendliness, high utility, remarkable physical mechanical properties, which make them particularly available CCS. In field capture, utilization sequestration...
Developing Cr-free and non-noble metal catalysts with high activity, selectivity durability for chemoselective hydrogenation of furfural to furfuryl alcohol is highly desirable yet challenging. In this study, we design a hollow mesoporous Co-N-C@mSiO2 nanostructure derived from ZIF-67 via the encapsulation-pyrolysis strategy. The catalyst exhibits excellent catalytic performance in towards good stability, much better than Co-N-C originating plain other reported transition catalysts....
Abstract Enhancing the covalent organic framework (COF)’s photocatalytic ability synergistically with gelling formulations remains an urgent challenge for extended bio‐applications. Herein, COF is homogeneously coated on oxidized carbon nanotube (OCNT) and coordinated by Fe 3+ to obtain tubular nanocomplex OCNT@COF‐Fe (O@CF). The results showed that photodynamic reactive oxygen species (ROS) generation of O@CF enhanced due wrapped OCNT , which can respectively serve as intermolecular charge...
The survival and colonization of tumor cells at new locations involve a variety complex genetic, epigenetic, microenvironmental factors. TRIM24 was originally named transcription intermediary factor 1-alpha (TIF1α), which associated with cellular proliferation an oncogene in development. Here we provide the first evidence expression profile clinicopathological significance patients hepatocellular carcinoma (HCC). Immunohistochemistry employed to determine level HCC tissues noncancerous liver...
Abstract A thermodynamic model for calculating the mass action concentrations of structural units in CaO–SiO 2 –MgO–FeO–MnO–Al O 3 –CaF slags, i.e. , IMCT‐ N i model, has been developed based on ion and molecule coexistence theory (IMCT). The calculated comprehensive concentration iron oxides $N_{{\rm Fe}_{t} {\rm O}} $ compared with reported activity oxide $a_{{\rm 14 FeO‐containing slag systems from literatures. good agreement between indicates that can be successfully applied to predict...
The preoperative C-reactive protein/Albumin (CRP/Alb) ratio has been shown to be valuable in predicting the prognosis of patients with certain cancers. aim our study is explore its prognostic value renal cell carcinoma (RCC). A retrospective was performed 570 RCC underwent radical or partial nephrectomy including 541 who received full resection localized (T1-3 N0/+ M0) RCC. optimal cutoff CRP/Alb determined by receive operating characteristic (ROC) analysis. impact and other...
Renal tubulointerstitial fibrosis (TIF), characterized by epithelial-to-mesenchymal transition (EMT) of renal tubular epithelial cells, is the typical pathological alteration in diabetic nephropathy. Gentiopicroside (GPS), a natural compound with anti-inflammatory activity, has been demonstrated to alleviate glomerulosclerosis, whereas whether GPS inhibits TIF via regulating inflammation remains unclear. In this study, db/db mice and high glucose (HG)-stimulated cells (NRK-52E) were applied...