A5051024587- Probiotics and Fermented Foods
- RNA Research and Splicing
- Polysaccharides Composition and Applications
- Nuclear Structure and Function
- Proteins in Food Systems
- Pediatric health and respiratory diseases
- Extracellular vesicles in disease
- Immune Response and Inflammation
- Bone Metabolism and Diseases
- Meat and Animal Product Quality
- Caveolin-1 and cellular processes
- Polysaccharides and Plant Cell Walls
- Dialysis and Renal Disease Management
- Autophagy in Disease and Therapy
- RNA modifications and cancer
- Lipid metabolism and biosynthesis
- Gut microbiota and health
- Antimicrobial Peptides and Activities
- Protein Hydrolysis and Bioactive Peptides
- Microencapsulation and Drying Processes
- IL-33, ST2, and ILC Pathways
- Microbial Metabolites in Food Biotechnology
- Cancer-related molecular mechanisms research
- Genomics and Chromatin Dynamics
- Infant Nutrition and Health
Nantong University
2024
Second People's Hospital of NanTong
2024
Northeast Agricultural University
2020-2023
Guangdong Medical College
2023
Capital Medical University
2020-2022
Lactobacillus fermentum HY01 is a probiotic strain screened from traditional yak yogurt, which can effectively relieve enteritis and constipation. This study aimed to evaluate the effects of as an adjunct starter on quality storage yogurt. A total 36 main volatile flavor substances were detected in all samples. In particular, more aldehydes, esters, alcohols yogurt prepared by mixed fermentation L. MY105 (including Streptococcus thermophilus delbrueckii ssp. bulgaricus). The rheological...
The present study aimed to develop a soft soy cheese using Geotrichum candidum (G. candidum) on the basis of Chinese tofu. Soy was prepared by adding 3% lactic acid bacteria (LAB) starter, 0.3% CaCl2, and G. at 104 CFU/ml. And microbial, chemical, textural, sensory characteristics product were evaluated different maturation temperatures. We observed that numbers in increased rapidly 107–108 CFU/g after 21 days 10°C or 15°C, remained constant until 28 days. Moreover, greatly promoted...
Abstract Integrin‐based focal adhesion is one of the major mechanosensory in osteocytes. The aim this study was to mine hub genes associated with and investigate their roles osteoporosis based on data single‐cell RNA sequencing RNA‐sequencing. Two (FAM129A RNF24) same expression trend AUC values greater than 0.7 both GSE56815 GSE56116 cohorts were uncovered. nomogram created predict risk OP two genes. Subsequently, competing endogenous network established genes, 14 microRNAs five long...
Bovine milk-derived extracellular vesicles (EVs) have been proved to positive effects on innate immunity and intestinal health. However, the effect of different processing treatments biological function EVs in dairy products remains unclear. Thus, we explored immunomodulatory from (pasteurized milk, UHT freeze-dried powder organic milk powder) by constructing RAW264.7 cell model, most commonly used vitro model study immune responses screen for anti-inflammatory active substances. The results...
Our previous study has confirmed that Lactobacillus acidophilus KLDS 1.0738 (La 1.0738) could alleviate β-lactoglobulin (β-Lg)-induced allergic inflammation. This further explored its molecular regulation mechanism through an in vitro macrophage model. β-Lg-induced macrophages were treated with strains of viable or non-viable L. and Toll-like receptor 4 (TLR4) inhibitor miR-146a inhibitor. results revealed β-Lg stimulation led to the increased expression TLR4/NF-κB signal pathway...
Abstract Non‐coding RNA 886 (nc886/VTRNA2‐1) is a Pol III transcript and an atypical imprinted gene. Its exact function as negative regulator of protein kinase R establishes its connection with innate immunity. Studies have shown that nc886 silencing closely associated prostate cancer progression. Previous work has constructed cell model stable overexpression (“mimic” or “nc886 + ”) in PC‐3M‐1E8 lines (1E8), which are highly bone‐metastatic human cells low expression nc886, expressing the...
The roles of lamin A/C in adipocyte differentiation and skeletal muscle lipid metabolism are associated with familial partial lipodystrophy Dunnigan (FPLD). We confirmed that LMNA knockdown (KD) mouse adipose-derived mesenchymal stem cells (AD-MSCs) prevented maturation. Importantly, vitro experiments, we discovered a significant increase phosphorylated levels at serine 22 or 392 sites (pLamin A/C-S22/392) accompanying increased synthesis liver cell line (7701 cells) two hepatocellular...
Laminopathies are a spectrum of diseases caused by LMNA mutations. In familial partial lipodystrophy Dunnigan (FPLD), plays role in the differentiation and development adipocytes lipid metabolism. Changes predict not only adipose-derived mesenchymal stem cells (AD-MSCs) but also transformation cancer cells. Hence, our in-depth study aimed to identify molecular connection between disordered metabolism hepatic carcinogenesis. We first discovered significant positive correlations pLMNA two key...