A5029134267- Health Systems, Economic Evaluations, Quality of Life
- Frailty in Older Adults
- Balance, Gait, and Falls Prevention
- Geriatric Care and Nursing Homes
- Chronic Disease Management Strategies
- Testicular diseases and treatments
- Hearing Loss and Rehabilitation
- Delphi Technique in Research
- Nutrition and Health in Aging
- Neuroblastoma Research and Treatments
- Stroke Rehabilitation and Recovery
- Hip and Femur Fractures
- Cerebral Palsy and Movement Disorders
- Health Policy Implementation Science
- Noise Effects and Management
- Musculoskeletal pain and rehabilitation
- Primary Care and Health Outcomes
- Bone fractures and treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Intensive Care Unit Cognitive Disorders
- Physical Activity and Health
- Healthcare Policy and Management
- Sinusitis and nasal conditions
- Diabetic Foot Ulcer Assessment and Management
- Neuroscience and Music Perception
University of Nottingham
2016-2025
Nottingham University Hospitals NHS Trust
2013-2024
Nottingham Biomedical Research Centre
2021-2023
Queen's Medical Centre
1999-2022
Memphis VA Medical Center
2021
NHS Lothian
2021
Florey Institute of Neuroscience and Mental Health
2020
The University of Melbourne
2020
Austin Health
2020
Peninsula Health
2020
Exercise and physical activity can improve bone strength the risk of falls, which may offer benefits in prevention management osteoporosis. However, uncertainty about types exercise that are safe effective instigates lack confidence people with osteoporosis health professionals. Existing guidelines leave some questions unresolved. This consensus statement aimed to determine needed optimise strength, reduce fall fracture risk, posture manage vertebral symptoms, while minimising potential...
PURPOSE: To evaluate carboplatin, etoposide, and bleomycin (JEB) in children with malignant extracranial germ cell tumors (GCTs). PATIENTS AND METHODS: Malignant GCTs aged 0 to 16 years were excised without major morbidity or otherwise biopsied. Stage I testicular some ovarian resected monitored alpha-fetoprotein (AFP) (“watch-and-wait” approach). Patients recurrent stage disease all other patients received JEB (etoposide 120 mg/m 2 on days 1 through 3, carboplatin 600 day 2, 15 3). Courses...
Abstract Objectives To determine the clinical and cost effectiveness of a multifactorial fall prevention programme compared with usual care in long term homes. Design Multicentre, parallel, cluster randomised controlled trial. Setting Long homes UK, registered to for older people or those dementia. Participants 1657 consenting residents 84 39 were intervention group 45 care. Interventions Guide Action Care Homes (GtACH): Main outcome measures Primary measure was rate at 91-180 days after...
In a 2 year double blind controlled trial of cyclosporin against placebo in multiple sclerosis conducted at two centres there was beneficial effect the therapy upon progression disease, relapse rate and severity one where patients received mean dose 7.2 mg/kg/day. This not seen other centre lower (mean 5 mg/kg/day) given. Reduction clinical accompanied by decreased IgG synthesis central nervous system. Side effects included hypertension, renal insufficiency anaemia were such to preclude use...
In the UK there has been little assessment of efficacy therapy for patients with dysphonia. Current objective methods (e.g. acoustical analysis) do not correlate well patient symptoms. Existing subjective measures are based on clinical impression. To date, no measure patient’s experience and aim this study was to explore difficulties that encounter as a consequence their illness or disability. One hundred thirty-three dysphonic completed an open-ended questionnaire where they were asked make...
Trials are at risk of contamination bias which can occur when participants in the control group inadvertently exposed to intervention. This is a particular rehabilitation studies where it easy for trial interventions be either intentionally or adopted settings. The Falls Care Homes (FinCH) used this paper as an example large randomised controlled complex intervention explore potential risks bias. We outline FinCH design, present from bias, and strategies design minimise mitigate against...
The measurement of a patient's health-related quality life following acoustic neuroma surgery is important because the itself can impose significant symptoms postoperatively. This study describes most common problems experienced by patients, using an open-ended questionnaire mailed to series 70 patients who had undergone surgery. Patient responses were classified impairment, disability and handicap, according World Health Organization (WHO) classification. Results showed that this group wide...
AIMS/BACKGROUND. Endonasal laser dacryocystorhinostomy (ELDCR) has recently become established as an alternative technique to conventional external DCR (EXDCR) for relief of epiphora. The aim this study was compare quality life and symptomatic outcomes in patients treated by these two methods. METHODS. A postal questionnaire sent 204 ELDCR 78 EXDCR who had undergone surgery under our care more than 6 months previously. included the validated 18-item Glasgow Benefit Inventory (GBI) 5 further...
Chair based exercise (CBE) is suggested to engage older people with compromised health and mobility in an accessible form of exercise. A systematic review looking at the benefits CBE for identified a lack clarity regarding definition, delivery, purpose benefits. This study aimed utilise expert consensus define develop core set principles guide practice future research. The framework was constructed through team workshop identifying 42 statements within 7 domains. four round electronic Delphi...
Abstract Purpose To investigate the longitudinal associations between pain and falls risks in adults. Methods Prospective cohort study on data from 40,636 community-dwelling adults ≥ 50 years assessed Wave 5 6 Survey of Health, Ageing Retirement Europe (SHARE). Socio-demographic clinical information was collected at baseline (Wave 5). At 2-year follow-up 6), previous months were recorded. The intensity, number sites specific anatomic sites, respectively, risk analysed by binary logistic...
Abstract Background National and international guidelines on frailty assessment management recommend screening in older people. This study aimed to determine how Brazilian healthcare professionals (HCPs) identify manage practice. Methods An anonymous online survey the of was circulated virtually through HCPs across Brazil. Results Most respondants used non-specific criteria such as gait speed (45%), handgrip strength (37.6%), comprehensive geriatric (33.2%). The use frailty-specific lower...
Abstract Background People living in care homes often have problems with pain, anxiety and depression. Whether being on analgesia, anxiolytics or antidepressants has any bearing pain severity quality of life (QoL) this population, requires further investigation. Objectives (i) to examine the relationship between depression medication use home residents (ii) compare those medications treat depression, who were not, associations overall QoL. Methods This was a secondary analysis randomised...
Previous work has shown that a normally aided ear tested without the hearing aid is better able to identify speech-in-noise than unaided at high sound levels, while performance for superior lower levels [S. Gatehouse, J. Acoust. Soc. Am. 86, 2103–6 (1989); 92, 1258–68 (1992)]. This effect was further explored using intensity discrimination complex stimuli. Stimuli were half-octave bandpass-filtered tone complexes centered 0.25 and 3 kHz. Four bilateral, symmetric hearing-impaired listeners...
Falls in care home residents are common, unpleasant, costly and difficult to prevent.
Abstract Introduction Neuromuscular electrical stimulation (NMES) is a treatment to prevent or reverse acquired disability in hospitalised adults. We conducted systematic review and meta-analysis of its effectiveness. Method searched MEDLINE, EMBASE, Cumulative Index Nursing & Allied Health (CINAHL) the Cochrane library. Inclusion criteria: randomised controlled trials adult patients comparing NMES control usual care. The primary outcome was muscle strength. Secondary outcomes were size,...
Frailty is a common condition that leads to multiple adverse outcomes. should be identified and managed in holistic, evidence-based patient-centered way. We aimed understand how UK healthcare professionals (HCPs) identify manage frailty comparison with Fit for guidelines, their training, confidence providing support organizational pathways this. An online mixed-methods survey was distributed HCPs supporting older people through professional bodies, special interest groups, key contacts,...