A5087650984- Total Knee Arthroplasty Outcomes
- Musculoskeletal pain and rehabilitation
- Orthopaedic implants and arthroplasty
- Knee injuries and reconstruction techniques
- Hip disorders and treatments
- Cerebral Palsy and Movement Disorders
- Hip and Femur Fractures
- Scoliosis diagnosis and treatment
- Orthopedic Infections and Treatments
- Shoulder Injury and Treatment
- Spine and Intervertebral Disc Pathology
- Stroke Rehabilitation and Recovery
- Osteoarthritis Treatment and Mechanisms
- Clinical practice guidelines implementation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Systems, Economic Evaluations, Quality of Life
- Musculoskeletal Disorders and Rehabilitation
- Bone fractures and treatments
- Empathy and Medical Education
- Pain Management and Placebo Effect
- Healthcare Systems and Challenges
- Orthopedic Surgery and Rehabilitation
- Neuroblastoma Research and Treatments
- Spinal Fractures and Fixation Techniques
- Lower Extremity Biomechanics and Pathologies
University of Oxford
2016-2025
Nuffield Orthopaedic Centre
2016-2025
Oxford University Hospitals NHS Trust
2015-2024
Oxford Brookes University
2013-2024
National Institute for Health Research
2018-2022
Oxford Research (Norway)
2022
National Health Service
2010-2022
Government of the United Kingdom
2022
Oxford Health NHS Foundation Trust
2022
NIHR Oxford Musculoskeletal Biomedical Research Centre
2011-2022
To assess the clinical effectiveness of surgical stabilisation (spinal fusion) compared with intensive rehabilitation for patients chronic low back pain.
In Brief Study Design. Prospective, cross-sectional observational study. Objectives. The aim of this study was to determine if there an association between wasting psoas and multifidus as observed on MRI scans the presenting symptoms, reported pathology, pain, or disability a cohort patients with unilateral low back pain. Summary Background Data. Current physiotherapy practice is often based localized spine stabilizing muscle exercises; most attention has been focused transversus abdominus...
Abstract Small and medium sized enterprises (SMEs) can gain a competitive advantage create sustainable business by adopting environmental good practices. However, the perceptions of SMEs their approach to improvements suggest that there are some fundamental misunderstandings difficulties in achieving this practice. A questionnaire‐based study responses current requirements practice was carried out South Yorkshire. Follow‐up interviews factory visits were also out. The aimed assess ability...
This prospective study describes the outcome of first 1000 phase 3 Oxford medial unicompartmental knee replacements (UKRs) implanted using a minimally invasive surgical approach for recommended indications by two surgeons and followed up independently. The mean follow-up was 5.6 years (1 to 11) with 547 knees having minimum five years. At their score 41.3 (sd 7.2), American Knee Society Objective Score 86.4 13.4), Functional 86.1 16.6), Tegner activity 2.8 1.1). For entire cohort, maximum...
Studies that systematically search for and synthesise qualitative research are becoming more evident in health care, they can make an important contribution to patient care. Our team was funded complete a meta-ethnography of patients' experience chronic musculoskeletal pain. It has been 25 years since Noblit Hare published their core text on meta-ethnography, the current environment brings additional challenges researchers aiming research. propose seven stages which take researcher from...
BackgroundLate-stage isolated medial knee osteoarthritis can be treated with total replacement (TKR) or partial (PKR). There is high variation in treatment choice and little robust evidence to guide selection. The Total Partial Knee Arthroplasty Trial (TOPKAT) therefore aims assess the clinical effectiveness cost-effectiveness of TKR versus PKR patients compartment knee, this represents an analysis main endpoints at 5 years.MethodsOur multicentre, pragmatic randomised controlled trial was...
Abstract Objective To compare arthroscopic hip surgery with physiotherapy and activity modification for improving patient reported outcome measures in patients symptomatic femoroacetabular impingement (FAI). Design Two group parallel, assessor blinded, pragmatic randomised controlled trial. Setting Secondary tertiary care centres across seven NHS England sites. Participants 222 participants aged 18 to 60 years FAI confirmed clinically imaging (radiography or magnetic resonance imaging) were...
Exercise and physical activity can improve bone strength the risk of falls, which may offer benefits in prevention management osteoporosis. However, uncertainty about types exercise that are safe effective instigates lack confidence people with osteoporosis health professionals. Existing guidelines leave some questions unresolved. This consensus statement aimed to determine needed optimise strength, reduce fall fracture risk, posture manage vertebral symptoms, while minimising potential...
Anterior cruciate ligament (ACL) rupture is a common debilitating injury that can cause instability of the knee. We aimed to investigate best management strategy between reconstructive surgery and non-surgical treatment for patients with non-acute ACL persistent symptoms instability.We did pragmatic, multicentre, superiority, randomised controlled trial in 29 secondary care National Health Service orthopaedic units UK. Patients symptomatic knee problems (instability) consistent an were...
Access to pain relief is a fundamental human right, yet child and adolescent can remain unheard untreated . We aimed understand testify young people's experiences. This the first systematic review of qualitative research present findings as poetry. followed stages meta-ethnography, using verbatim poetry express findings. included 189 studies incorporating 6072 people with across range conditions contexts. Our highlight ambiguity exacerbated by unpredictability, absence diagnosis, tangle...
This prospective study describes the complications and survival of first 688 Phase 3 Oxford medial unicompartmental knee replacements implanted using a minimally-invasive technique by two surgeons followed up independently. None was lost to follow-up. We had carried out 132 procedures more than five years ago. The clinical assessment 101 these which were available for review at is also presented. Nine knees revised: four infection, three dislocation bearing unexplained pain. A further seven...
Current musculoskeletal outcome tools are fragmented across different healthcare settings and conditions. Our objectives were to develop validate a single measure for use throughout the pathway patients with conditions: Arthritis Research UK Musculoskeletal Health Questionnaire (MSK-HQ).
Studies that systematically search for and synthesise qualitative research are becoming more evident in health care, they can make an important contribution to patient care. However, there is still no agreement as whether, or how we should appraise studies inclusion. We aimed explore the intuitive processes determined 'quality' of inclusion syntheses. were particularly interested way knowledge was constructed.We used methods process quality appraisal within a team seven researchers funded...
Each year over five million people develop chronic non-malignant pain and can experience healthcare as an adversarial struggle. The aims of this study were: (1) to bring together qualitative evidence syntheses that explore patients’ living with conceptual understanding what it is like live for improved healthcare; (2) undertake the first mega-ethnography using methods meta-ethnography. We used seven stages meta-ethnography refined large studies. innovation use findings from primary data....
BackgroundCorticosteroid injections and physiotherapy exercise programmes are commonly used to treat rotator cuff disorders but the treatments' effectiveness is uncertain. We aimed compare clinical cost-effectiveness of a progressive programme with single session best practice advice, or without corticosteroid injection, in adults disorder.MethodsIn this pragmatic, multicentre, superiority, randomised controlled trial (2 × 2 factorial), we recruited patients from 20 UK National Health...
Abstract Objective There is a large body of research exploring what it means for person to live with chronic pain. However, existing does not help us understand recover. We aimed identify qualitative that explored the experience living pain published since 2012 and process recovery. Design A synthesis using meta-ethnography. Methods used seven stages systematically searched research, 2012, adults’ experiences with, being treated for, constant comparison distill essence ideas into themes...