A5035652235- Diet and metabolism studies
- Dietary Effects on Health
- Mobile Health and mHealth Applications
- Nutritional Studies and Diet
- Regulation of Appetite and Obesity
- Physical Activity and Health
- Diet, Metabolism, and Disease
- Adipose Tissue and Metabolism
- Obesity, Physical Activity, Diet
- Osteoarthritis Treatment and Mechanisms
- Knee injuries and reconstruction techniques
- Exercise and Physiological Responses
- Radiation Therapy and Dosimetry
- Behavioral Health and Interventions
- Obesity and Health Practices
- Eating Disorders and Behaviors
- Biochemical Analysis and Sensing Techniques
- Lipid metabolism and disorders
- Laser-Ablation Synthesis of Nanoparticles
- Musculoskeletal pain and rehabilitation
- Boron Compounds in Chemistry
- Health and Lifestyle Studies
- Circadian rhythm and melatonin
- Nutrition, Genetics, and Disease
- Adipokines, Inflammation, and Metabolic Diseases
Versus Arthritis
2021-2025
University of Bath
2014-2024
Queen's Medical Centre
2014
Background: The causal nature of associations between breakfast and health remain unclear in obese individuals. Objective: We sought to conduct a randomized controlled trial examine links habits components energy balance free-living humans. Design: Bath Breakfast Project is with repeated measures at baseline follow-up among cohort South West England aged 21–60 y dual-energy X-ray absorptiometry–derived fat mass indexes ≥13 kg/m2 for women (n = 15) ≥9 men 8). Components (resting metabolic...
Popular beliefs that breakfast is the most important meal of day are grounded in cross-sectional observations link to health, causal nature which remains be explored under real-life conditions.
Wearable physical activity monitors are growing in popularity and provide the opportunity for large numbers of public to self-monitor behaviours. The latest generation these devices feature multiple sensors, ostensibly similar or even superior advanced research instruments. However, little is known about accuracy their energy expenditure estimates. Here, we assessed performance against criterion measurements both controlled laboratory conditions (simulated activities daily living structured...
Daily energy restriction more effectively reduces body fat content than alternate-day fasting, with no evidence of fasting-specific health benefits.
Breakfast omission is associated with obesity and CVD/diabetes, but the acute effects of extended morning fasting upon subsequent energy intake metabolic/hormonal responses have received less attention. In a randomised cross-over design, thirty-five lean men ( n 14) women 21) their overnight fast or ingested typical carbohydrate-rich breakfast in quantities relative to RMR (i.e. 1963 sd 238) kJ), before an ad libitum lunch 3 h later. Blood samples were obtained hourly throughout day until...
Breakfast omission is positively associated with obesity and increased risk of disease. However, little known about the acute effects extended morning fasting upon subsequent energy intake metabolic/regulatory factors in obese adults. In a randomised cross-over design, 24 men (n=8) women (n=16) their overnight fast by omitting breakfast consumption or ingesting typical carbohydrate-rich 2183±393 kJ (521±94 kcal), before an ad libitum pasta lunch 3 h later. Blood samples were obtained...
Abstract Background The intelligent knee osteoarthritis lifestyle app (iKOALA) has been co-developed with target users to extend the support for physical activity (PA) and musculoskeletal health, beyond short-term structured rehabilitation, using personalised PA guidance, education, social support. purpose of this study was assess preliminary effectiveness usability iKOALA digital intervention on indices (MSK) symptoms, levels in a broad range individuals (KOA) over 12 weeks inform design...
Abstract Background Current guidance regarding the role of daily breakfast in human health is largely grounded cross-sectional observations. However, causal nature these relationships has not been fully explored and what limited information emerging from controlled laboratory-based experiments appears inconsistent with much existing data. Further progress our understanding therefore requires a direct examination how impacts under free-living conditions. Methods/Design The Bath Breakfast...
Key points In lean individuals, 6 weeks of extended morning fasting increases the expression genes involved in lipid turnover ( ACADM ) and insulin signalling IRS2 subcutaneous abdominal adipose tissue. obese The content activation status key proteins glucose transport (GLUT4, Akt1 Akt2) were unaffected by fasting. Therefore, any observations altered tissue sensitivity with do not necessarily require changes proximal to Akt. Insulin‐stimulated uptake rates are lower versus but this...
Abstract Background Technological progress has enabled the provision of personalised feedback across multiple dimensions physical activity that are important for health. Whether this multidimensional approach supports behaviour change not yet been examined. Our objective was to examine effectiveness a novel digital system and app provided combined with health trainer support in primary care patients identified as at risk chronic disease. Methods MIPACT parallel-group, randomised controlled...
It remains unknown whether sustained daily feeding-fasting patterns modify the acute response to specific feedings on a given day. We conducted randomized controlled trial establish if breakfast consumption or fasting until noon modifies metabolic and appetitive responses fixed ad libitum lunch. With use of parallel group design, we randomly assigned 31 healthy, lean men women (22–56 y) 6 wk either consuming ≥700 kcal self-selected items before 1100 (0 kcal) 1200 daily. Following 48 h diet...
Abstract Background Knee osteoarthritis is one of the most prevalent long term health conditions globally. Exercise and physical activity are now widely recognised to significantly reduce joint pain, improve function quality life in patients with knee osteoarthritis. However, prescribed exercise without regular contact a healthcare professional often results lower adherence poorer outcomes. Digital mobile (mHealth) technologies offer great potential support people long-term such as more...
Objective The aim of this study was to determine the effects sustained morning fasting or breakfast consumption on metabolism, energy intake, and appetite in healthy adults with obesity. Methods An independent‐measures randomized controlled trial baseline follow‐up laboratory assessment days separated by a 6‐week intervention either (0 kcal until 12:00 pm ) daily (> 700 11:00 am performed. Measures included metabolic outcomes (glucose, insulin, nonesterified fatty acids), hormones...
This study investigated the effect of 3 weeks high-sugar ("Sweet") versus low-sugar ("Plain") breakfast on energy balance, metabolic health, and appetite.A total 29 healthy adults (22 women) completed this randomized crossover study. Participants had pre- postintervention appetite, body mass outcomes measured, they recorded diet, appetite (visual analogue scales), physical activity for 8 days during each intervention. Interventions were isoenergetic Sweet (30% by weight added sugar; average...
Abstract Omission of a carbohydrate‐rich breakfast followed by consuming an ad libitum lunch impairs evening exercise performance. However, it is unclear if this due to omission per se , or secondary lower carbohydrate intake over the day. To test whether impaired performance following persists when complete dietary compensation occurs at lunch, in randomised cross‐over design, eleven highly trained cyclists (age: 25 ± 7 y, VO 2 max: 61 5 ml·kg −1 ·min ) completed two trials: (B) and no...
Weight loss following prolonged energy restriction and/or exercise can reduce biomarkers of systemic inflammation and improve pain function in individuals with knee osteoarthrosis (KOA). However, the short-term effects diet exercise, absence significant reduction fat mass, on markers inflammation, remains unclear. PURPOSE: The primary aim this randomized controlled trial was to determine whether acute restriction, or without effective altering joint patients KOA. METHODS: Fourteen men...
Some patients with chronic knee pain experience an increase in following a single bout of exercise involving their joint, which can negatively affect adherence and thus result reduced overall health lack disease management. We want to determine whether upper-body (UB) aerobic arm-ergometry is effective reducing the those compared lower-body (LB) leg ergometry exercise.A total 19 individuals (women = 11, men 8; age 63 ± 8 years; body mass index 24 3 kg/m2) who suffered from for ≥3 months took...