A5017915765- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury Research
- Sepsis Diagnosis and Treatment
- Maternal Mental Health During Pregnancy and Postpartum
- Emergency and Acute Care Studies
- Maternal and Perinatal Health Interventions
- Child and Adolescent Health
- Nursing Roles and Practices
- Trauma and Emergency Care Studies
- Ethics in Clinical Research
- Child and Adolescent Psychosocial and Emotional Development
- Bullying, Victimization, and Aggression
- Intracranial Aneurysms: Treatment and Complications
- Poisoning and overdose treatments
- Hemodynamic Monitoring and Therapy
- Ultrasound in Clinical Applications
- Data Quality and Management
- Neonatal Respiratory Health Research
- Plant Virus Research Studies
- Ethics and Legal Issues in Pediatric Healthcare
- BRCA gene mutations in cancer
- Electronic Health Records Systems
- Iron Metabolism and Disorders
- Genomics and Rare Diseases
Duke University
2016-2025
Duke University Health System
2016-2024
American Association of Nurse Practitioners
2022
Robert Wood Johnson Foundation
2016-2020
University of Alabama at Birmingham
2020
E Ink (South Korea)
2020
National Institutes of Health
2019
Child, Adolescent and Family Mental Health
2018
Biostats (United States)
2017
Rady Children's Hospital-San Diego
2008-2016
Objectives: The American College of Critical Care Medicine provided 2002 and 2007 guidelines for hemodynamic support newborn pediatric septic shock. Provide the 2014 update “Clinical Guidelines Hemodynamic Support Neonates Children with Septic Shock.” Design: Society members were identified from general solicitation at Educational Scientific Symposia (2006–2014). PubMed/Medline/Embase literature (2006–14) was searched by librarian using keywords: sepsis, septicemia, shock, endotoxemia,...
Severe Traumatic Brain Injury in Infants, Children, and Adolescents 2019: Some Overdue Progress, Many Remaining Questions, Exciting Ongoing Work the Field of Research In this Supplement to Pediatric Critical Care Medicine, we are pleased present Third Edition Guidelines for Management (TBI). This body work updates Second guidelines that was published 2012 (1). It represents a substantial effort by multidisciplinary group individuals assembled reflect team approach treatment these complex,...
To produce a treatment algorithm for the ICU management of infants, children, and adolescents with severe traumatic brain injury.Studies included in 2019 Guidelines Management Pediatric Severe Traumatic Brain Injury (Glasgow Coma Scale score ≤ 8), consensus when evidence was insufficient to formulate fully evidence-based approach, selected protocols from studies.Baseline care germane all pediatric patients injury along two tiers therapy were formulated. An approach emergent crisis scenario...
Abstract The purpose of this work is to identify and synthesize research produced since the second edition these Guidelines was published incorporate new results into revised evidence-based recommendations for treatment severe traumatic brain injury in pediatric patients. This document provides an overview our process, lists added, includes recommendations. Recommendations are only provided when there supporting evidence. update 22 recommendations, 9 or from previous editions. New on...
The purpose of this work is to identify and synthesize research produced since the second edition these Guidelines was published incorporate new results into revised evidence-based recommendations for treatment severe traumatic brain injury in pediatric patients.This document provides an overview our process, lists added, includes recommendations. Recommendations are only provided when there supporting evidence. This update 22 recommendations, nine or from previous editions. New on...
Objectives: To develop the first core Critical Care Data Dictionary (C2D2) with common data elements (CDEs) to characterize critical illness and injuries. Design: Group consensus process using modified Delphi approach. Setting: Electronic surveys in-person meetings. Subjects: A multidisciplinary workgroup of clinicians researchers expertise in care critically ill injured. Interventions: The was divided into domain CDE portions each composed two item generation rounds one reduction/refinement...
Davis, Alan L. MD, MPH, FAAP, FCCM; Carcillo, Joseph A. MD; Aneja, Rajesh K. Deymann, Andreas J. Lin, John C. Nguyen, Trung Okhuysen-Cawley, Regina S. FAAP; Relvas, Monica MSHA, Rozenfeld, Ranna Skippen, Peter W. MBBS, FRCPC; Stojadinovic, Bonnie DNP, CPNP; Williams, Eric MS, MMM; Yeh, Tim MCCM; Balamuth, Fran Brierley, Joe MA; de Caen, Allan R. Cheifetz, Ira M. Choong, Karen MSc, MB, Bch; Conway, Edward Jr Cornell, Timothy Doctor, Dugas, Marc-Andre MSc; Feldman, Jonathan D. Fitzgerald,...
The aim of this study was to determine the relationship between transcranial Doppler (TCD) derived pulsatility index (PI), end diastolic flow velocity (Vd), and intracranial pressure (ICP). subjects in were 36 children admitted after severe traumatic brain injury (TBI) (postresuscitation Glasgow Coma Scale ≤ 8) undergoing invasive ICP monitoring.Subjects underwent a total 148 TCD studies. measurements systolic (Vs), Vd, mean (Vm) performed on middle cerebral artery (MCA) ipsilateral monitor....
To determine the incidence of vasospasm in children who have suffered moderate to severe traumatic brain injury.A prospective observational pilot study a 24-bed pediatric intensive care unit was performed. Twenty-two aged 7 months 14 years with injury as indicated by Glasgow Coma Score </=12 and abnormal head imaging were enrolled. Transcranial Doppler ultrasound performed identify follow vasospasm. Patients flow velocity middle cerebral artery (MCA) >120 cm/s considered criterion A. If MCA...
Abstract Transcranial Doppler ultrasonography (TCD) is being used in many pediatric intensive care units (PICUs) to aid the diagnosis and monitoring of children with known or suspected pathophysiological changes cerebral hemodynamics. Standardized approaches scanning protocols, interpretation, documentation TCD examinations this setting are lacking. A panel multidisciplinary clinicians expertise use PICU undertook a three-round modified Delphi process reach unanimous agreement on 34...
To explore changes to expected, age-related transcranial Doppler ultrasound variables during pediatric extracorporeal membrane oxygenation.Prospective, observational, multicenter study.Tertiary care PICUs.Children 1 day 18 years old requiring veno arterial oxygenation.Participants underwent daily measurement of bilateral middle cerebral artery flow velocities. Acute neurologic injury was diagnosed if seizures, hemorrhage, or diffuse ischemia detected.Fifty-two children were enrolled and...
The scope of transcranial Doppler ultrasound in the practice pediatric neurocritical care is unknown. We have surveyed centers on their use and analyzed clinical management practices.Electronic-mail recruitment with survey expert using web-based questionnaire.Survey 43 hospitals (31 United States, 12 international) belonging to Pediatric Neurocritical Care Research Group.None.None.A 67% (29/43) hospital-response rate. Of these centers, 27 reported PICU; two opted out due lack...
Substitutable Medical Apps Reusable Technologies (SMART® ) on Fast Healthcare Interoperability Resources (FHIR) is an open, standards platform that allows third parties to build health applications interact with electronic record (EHR) systems. This can allow for aggregation of unique data ranging from genomics lifestyle, thereby promoting the emerging precision medicine approach. It also first provide a way successfully incorporate interoperability in EHRs and implementation.
Clinical practice guidelines are essential for promoting evidence-based healthcare. While diversification of panel members can reduce disparities in care, processes selection lack transparency. We aim to share our approach forming a diverse expert the updated Adult Critical Care Ultrasound Guidelines.