- Remote-Sensing Image Classification
- Remote Sensing and Land Use
- Advanced Image Fusion Techniques
- Seismic Imaging and Inversion Techniques
- Hydrocarbon exploration and reservoir analysis
- Advanced Thermoelectric Materials and Devices
- Advancements in Semiconductor Devices and Circuit Design
- Semiconductor Quantum Structures and Devices
- Topological Materials and Phenomena
- Machine Fault Diagnosis Techniques
- Image Retrieval and Classification Techniques
- Drilling and Well Engineering
- Air Quality and Health Impacts
- Physics of Superconductivity and Magnetism
- Nanowire Synthesis and Applications
- Surface and Thin Film Phenomena
- Quantum and electron transport phenomena
- Gear and Bearing Dynamics Analysis
- Renal Diseases and Glomerulopathies
- Advanced Thermodynamics and Statistical Mechanics
- Graphene research and applications
- Molecular Junctions and Nanostructures
- Atmospheric chemistry and aerosols
- Complement system in diseases
- Alzheimer's disease research and treatments
Harbin Medical University
2023-2025
China University of Petroleum, Beijing
2024-2025
Shanxi Province Hospital of Traditional Chinese Medicine
2024-2025
Tianjin University of Science and Technology
2025
Dalian Medical University
2024
Chongqing Medical University
2024
Second Affiliated Hospital of Chongqing Medical University
2024
Sun Yat-sen University
2022-2024
Sun Yat-sen University Cancer Center
2022-2024
China University of Geosciences (Beijing)
2021-2024
Probing an isolated Majorana zero mode is predicted to reveal a tunneling conductance quantized at $2e^2/h$ temperature. Experimentally, zero-bias peak (ZBP) expected and its height should remain robust against relevant parameter tuning, forming plateau. Here, we report the observation of large ZBPs in thin InAs-Al hybrid nanowire device. The ZBP can stick close $2e^2/h$, mostly within $5\%$ tolerance, by sweeping gate voltages magnetic field. We further map out phase diagram identify two...
Background Obesity is a metabolic and chronic inflammatory disease involving genetic environmental factors. This study aimed to investigate the causal relationship among gut microbiota abundance, plasma metabolomics, peripheral cell (blood immune cell) counts, cytokines, obesity. Methods Summary statistics of 191 traits (N = 18,340), 1,400 metabolite 8,299), 128 counts cells, N 408,112; 3,757), 41 cytokine 8,293), 6 obesity were obtained from publicly available genome-wide association...
Hybrid semiconductor-superconductor InAs-Al nanowires with uniform and defect-free crystal interfaces are one of the most promising candidates used in quest for Majorana zero modes (MZMs). However, InAs often exhibit a high density randomly distributed twin defects stacking faults, which result an uncontrolled non-uniform interface. Furthermore, this type disorder can create potential inhomogeneity wire, destroy topological gap, form trivial sub-gap states mimicking MZM transport...
Silica nanoparticle (SiNP) exposure induces severe pulmonary inflammation and fibrosis, but the pathogenesis remains unclear, effective therapies are currently lacking. To explore mechanism underlying SiNPs-induced we constructed in vivo silica animal models vitro of silica-induced macrophage pyroptosis fibroblast transdifferentiation. We found that SiNP elicits upregulation proteins associated with pyroptosis, including NLRP3, ASC, IL-1β, GSDMD, while immunofluorescence staining...
The prevalence of colorectal cancer (CRC) is increasing annually and metastasis the principal cause death in patients with CRC, liver being most frequently affected site. Many studies have shown a strong interplay between gut flora, particularly <i>Fusobacterium nucleatum</i> (<i>F. nucleatum</i>), <i>Escherichia coli</i>, <i>Bacteroides fragilis</i>, development tumors. Some strains can induce inflammation produce toxins that directly harm epithelial cells, ultimately accelerating onset...
Phospholipase A2 receptor 1 (PLA2R1) exists in many animals and plays an important role membranous nephropathy. In this study, we aimed to evaluate a PLA2R1 knock-in rat model with repaired kidney function study the molecular mechanisms of We constructed knockout [PLA2R1(-)] knock [PLA2R1(+)] rats. Consistent complement C3 IgA expression was confirmed through colocalization studies. Urinary biochemical indicators were performed using Automatic Biochemistry Analyzer. The C3, IgG, Nephrin...
Deep learning has made significant progress in hyperspectral image (HSI) classification, and its powerful ability to automatically learn abstract features is well recognized. Recently, the simple architecture of multi-layer perceptron (MLP) been extensively employed extract long-range dependencies HSI achieved impressive results. However, existing MLP-based models exhibit insufficient representation spectral–spatial information generally aggregate with fixed weights, which limits their...
ABSTRACT The pathogenicity of cholestatic liver diseases (CLDs) remains insufficiently characterized, hindering definitive diagnosis and timely treatment. aim this study was to improve the prediction novel bile acid (BA) transporter variants in patients with CLDs. We analyzed clinical characteristics genetic profiles a CLD cohort ( n = 57) using multiple silico tools vitro functional assays. identified 78 unique four BA genes. predominant defects were associated ABCC2 (57/78, 73.1%), most...
Amyloids are insoluble fibrillar aggregates that highly associated with complex human diseases, such as Alzheimer's disease, Parkinson's and type II diabetes. Recently, many studies reported some specific regions of amino acid sequences may be responsible for the amyloidosis proteins. It has become very important elucidating mechanism amyloids identifying amyloidogenic regions. Accordingly, several computational methods have been put forward to discover The majority these predicted based on...
Phospholipase A2 receptor 1 (PLA2R1) plays a crucial role in various diseases, including membranous nephropathy. However, the precise implications of PLA2R1 deficiency remain poorly understood. In this study, we created knockout rats to explore potential consequences resulting from loss gene. Unexpectedly, our exhibited symptoms resembling those chronic kidney disease after an 8-week observation period. Notably, several developed persistent proteinuria, hallmark renal dysfunction....
This study aimed to examine the prevalence and risk factors of Post-Traumatic Stress Symptoms (PTSS) in hospitalised children with cancer their parents explore PTSS correlation between children.
Polymer-ceramic dielectric composites have been of great interest because they combine the processability polymers with desired properties ceramics. We fabricated a low voltage-operated flexible organic field-effect transistor (OFET) based on crosslinked poly (4-vinyl phenol) (PVP) polymer blended novel ceramic calcium titanate nanoparticles (CaTiO3 NPs) as gate dielectric. To reduce interface roughness caused by nanoparticles, it was further coated very thin PVP film. The resulting OFET...
Circular RNAs (circRNAs) have important regulatory roles in the development of various cancers. However, biological functions and potential molecular mechanisms circRNAs hepatocellular carcinoma (HCC) are still unclear. In this study, we investigated role a new circRNA-circGSK3B (hsa_circ_0003763) its mechanism HCC. We found that circGSK3B was highly expressed HCC tissues cell lines. Additionally, expression level significantly correlated with tumor size vascular invasion. Functionally,...
Deep learning has dominated hyperspectral image (HSI) classification due to its modular design and powerful feature extraction capabilities. Recently, a modern macro-architecture-based framework with high-order interactions been proposed, inspiring the of HSI models. As spatial mixer in macro-architecture, interaction facilitates aggregation discriminative information by gated mechanisms standard convolutions. However, homogeneous operators convolution are challenging consider different...