Protein adhesion plays a major role in determining the biocompatibility of materials. The first stage implant integration is protein followed by cell attachment. Surface modification implants (surface chemistry and topography) to induce control currently great interest. This communication presents data on adsorption (bovine serum albumin fibrinogen) onto model hydrophobic (CH3) hydrophilic (OH) surfaces, investigated using quartz crystal microbalance (QCM) grazing angle infrared...

Protein adsorption behavior is at the heart of many today's research fields including biotechnology and materials science. With understanding protein-surface interactions, control over conformation orientation immobilized species may ultimately allow tailor-made surfaces to be generated. In this contribution interactions have been examined with particular focus on surface curvature without chemistry effects. Silica spheres diameters in range 15-165 nm both hydrophilic hydrophobic chemistries...

The incorporation of silica within the plant cell wall has been well documented by botanists and materials scientists; however, means which plants are able to transport silicon control its polymerization, together with roles in situ, not fully understood.

Super-hydrophobicity can be achieved on relatively smooth surfaces. Short, wide pillars slightly rough surfaces are shown to produce super-hydrophobic (see Figure) where neither the nor slight roughness suffice alone. This use of two length scales create directly mimics mechanism used by some plants including lotus.

Silica nanostructures find applications in drug delivery, catalysis, and composites, however, understanding of the surface chemistry, aqueous interfaces, biomolecule recognition remain difficult using current imaging techniques spectroscopy. A silica force field is introduced that resolves numerous shortcomings prior fields over last 30 years reduces uncertainties computed interfacial properties relative to experiment from several 100% less than 5%. In addition, a model database for full...

Intrinsically superhydrophobic foams with contact angles greater than 150° were prepared using a sol−gel phase-separation process. Hydrophobicity was built in by organofunctionalized inorganic monomers and setting the conditions so that they retained product. The materials characterized advancing receding water angle measurements, scanning electron microscopy, infrared spectroscopy. preparation method used simple produced roughness hydrophobicity same material, thus obviating need for...

We report a one-pot synthesis of spherical gold nanoparticles (52–22 nm) and their capping with cefaclor, second-generation antibiotic, without use other chemicals. The differently sized were fabricated by controlling the rate reduction ions in aqueous solution varying reaction temperature (20–70 °C). primary amine group cefaclor acted as both reducing agent for leaving β-lactam ring available activity against microbes. Antimicrobial testing showed that reduced have potent antimicrobial...

Control over selective recognition of biomolecules on inorganic nanoparticles is a major challenge for the synthesis new catalysts, functional carriers therapeutics, and assembly renewable biobased materials. We found low sequence similarity among sequences peptides strongly attracted to amorphous silica various size (15-450 nm) using combinatorial phage display methods. Characterization surface by acid base titrations zeta potential measurements revealed that acidity particles increased...

Rough and patterned copper surfaces were produced using etching and, separately, electrodeposition. In both of these approaches the roughness can be varied in a controlled manner when hydrophobized, show contact angles that increase with increasing to above 160 degrees . We transitions from Wenzel mode, whereby liquid follows contours surface, Cassie-Baxter bridges between features on surface. Measured etched samples could modeled quantitatively within few by equations. The angle hysteresis...

Roughening a hydrophobic surface enhances its nonwetting properties into superhydrophobicity. For liquids other than water, roughness can induce complete rollup of droplet. However, topographic effects also enhance partial wetting by given liquid to create superwetting. In this work, model system spreading droplets nonvolatile on surfaces having lithographically produced pillars is used show that superwetting modifies the dynamics spreading. The edge speed-dynamic contact angle relation...

Several studies have demonstrated the use of biomimetic approaches in synthesis a variety inorganic materials. Poly-l-lysine (PLL) promotes precipitation silica from silicic acid solution within minutes. The molecular weight PLL was found to affect morphology resulting precipitate. Larger-molecular produced hexagonal platelets, whereas spherical particles were obtained using low-molecular PLL. Here we report on polypeptide secondary-structure transition that occurs during silicification...

Molecular recognition and interactions at the interface between biomolecules inorganic materials determine important phenomena such as protein adsorption, cell adhesion to biomaterials, or selective response of biosensors. Events occurring biomolecule-inorganic interface, despite their importance, are still poorly understood, thus limiting control interfacial properties response. In this contribution, using well-characterized silica nanoparticles a series peptides having heterogeneous...

Silica skeletal architectures in diatoms are characterized by remarkable morphological and nanostructural details. Silk proteins from spiders silkworms form strong intricate self-assembling fibrous biomaterials nature. We combined the features of silk with biosilica through design, synthesis, characterization a novel family chimeric for subsequent use model materials forming reactions. The domains major ampullate spidroin 1 (MaSp1) protein Nephila clavipes spider dragline provide control...

Switching between superhydrophobicity and superhydrophilicity in porous materials was predicted theoretically demonstrated experimentally with the example of thermally induced contact angle change; tunability this system also demonstrated.

Most insects and spiders drown when submerged during flooding or tidal inundation, but some are able to survive others can remain indefinitely without harm. Many achieve this by natural adaptations their surface morphology trap films of air, creating plastrons which fix the water-vapor interface provide an incompressible oxygen-carbon dioxide exchange surface. Here authors demonstrate how extremely water-repellent foam mimics mechanism underwater respiration allows direct extraction oxygen...

Silica nanostructures are biologically available and find wide applications for drug delivery, catalysts, separation processes, composites. However, specific adsorption of biomolecules on silica surfaces control in biomimetic synthesis remain largely unpredictable. In this contribution, the variability peptide nanoparticle explained as a function pH, particle diameter, electrostatic charge using molecular dynamics simulations with CHARMM-INTERFACE force field. Adsorption free energies...

The controlled synthesis of ZnO at the micro- and nanoscale has been focus significant research due to its importance in electrical optoelectronic applications, potential tuning properties crystal formation stage. We present a detailed study growth processes which supports consolidates previous findings gives clearer understanding mechanism formation. influence conditions on was investigated by comparison two different routes (Zn(CH3COO)2–NH3 Zn(NO3)2·6H2O−HMTA) both known result wurtzite...