A5103081493- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Renal Diseases and Glomerulopathies
- Neonatal Respiratory Health Research
- Antifungal resistance and susceptibility
- Infant Development and Preterm Care
- interferon and immune responses
- Mosquito-borne diseases and control
- Atherosclerosis and Cardiovascular Diseases
- Nutrition, Health and Food Behavior
- Neonatal and fetal brain pathology
- Asthma and respiratory diseases
- Health and Wellbeing Research
- Physical Activity and Health
- Research on Leishmaniasis Studies
- Vasculitis and related conditions
- Pregnancy and preeclampsia studies
- Sepsis Diagnosis and Treatment
- Nonmelanoma Skin Cancer Studies
- Urinary Tract Infections Management
- Psoriasis: Treatment and Pathogenesis
- Neutropenia and Cancer Infections
- Phytochemicals and Medicinal Plants
- Inflammatory Myopathies and Dermatomyositis
- Influenza Virus Research Studies
University of Pittsburgh
2024-2025
University of Tsukuba
2018-2024
King Edward VIII Hospital
2024
University of KwaZulu-Natal
2022-2023
Suamandeep Vidyapeeth University
2021
University of Liverpool
2015
Children’s Foundation
2015
National Health Service
2015
ICMR-National Institute of Virology
2009
NewYork–Presbyterian Brooklyn Methodist Hospital
2003
We compared the validity of pancytopenia, formol-gel test (FGT), indirect fluorescence antibody (IFAT), direct agglutination (DAT), and rK39 dipstick as diagnostic criteria for visceral leishmaniasis (VL) in Nepal. Between September 2000 January 2002, 310 clinical suspects had a bone marrow aspirate, if negative, spleen aspirate smear examined Leishmania donovani. Sensitivity specificity all tests were determined with parasitology by latent class analysis (LCA). Compared parasitology,...
Introduction Influenza-associated pulmonary aspergillosis (IAPA) is a severe complication of influenza infection that occurs in critically ill patients and results higher mortality compared to alone. Interleukin-17 (IL-17) the Type 17 immune signaling pathway cytokine family are recognized for their pivotal role fostering protective immunity against various pathogens. In this study, we investigate IL-17 components during IAPA. Methods Wild-type mice were challenged with A H1N1 (flu) then...
Influenza infections are often complicated by secondary bacterial such as MRSA pneumonia, which increase morbidity and mortality. Viral lead to an inflammatory response that includes elevated levels of IL-6 interferons. activates the JAK/STAT signaling pathway, amplifying downstream inflammation. Given clinical efficacy JAK inhibitor baricitinib in reducing disease severity COVID-19, we evaluated its impact a murine model influenza, MRSA, post-influenza pneumonia. Additionally, because...
All-trans retinoic acid (atRA) plays a critical role in tissue homeostasis as master regulator of cellular proliferation, apoptosis and differentiation well immune cell function. An active metabolite vitamin A, atRA has been reported to be reduced number inflammatory conditions both the lung gut. Decreases have gastrointestinal bowel diseases, radiation-induced injury viral infection. In lung, is including allergic asthma injury; however, impact infection on not defined. this short...
Prevalence of systemic lupus erythematosus (SLE) was studied in the northern Indian population by means a two-pronged approach: (a) antinuclear antibody (ANA) screening general new well-standardized finger-prick 'filter paper' technique (sensitivity and specificity: 95.4% 86.2%, respectively); (b) questionnaire survey carried out primarily trained personnel community 100% 68.6% respectively). The low specificity two methods improved introduction step secondary authors, thus excluding false...
Data on the clinical and laboratory profiles of 83 children with SLE have been analysed compared data 187 adults disease. The features childhood are similar to those seen in adults, although parameters reflect propensity a more severe form disease juvenile age group. However, comparison descriptions lupus from developed countries, India female-to-male ratio this group parallels that adults. Renal involvement is noted be common, whereas gastro-intestinal haematological abnormalities less...
Abstract Japanese encephalitis virus (JEV) induces an acute infection of the central nervous system, pathogenic mechanism which is not fully understood. To investigate host response to JEV infection, 14‐day‐old mice were infected via extraneural route, resulted in and death. Mice that received immune splenocyte transfer protected from infection. Pathology gene expression profiles then compared brains either succumbed or by cell transfer. undergoing progressive had increased proinflammatory...
Neutrophilic eccrine hidradenitis (NEH) is an unusual self-limited skin disorder characterized by inflammatory cell infiltrate in the deep dermis involving sweat glands, commonly presenting as painful cutaneous nodules. NEH occurs most frequently patients receiving chemotherapy for haematologic malignancies. We report a case of masquerading vasculitis woman cyclophosphamide lupus nephritis. The association and use cytotoxic agents SLE or other autoimmune diseases has not been reported...
Abstract Background Pelvic organ prolapse (POP) is one of the main contributors to reproductive health problems that affect women’s quality life. Previous studies have reported risk factors and prevalence POP. The aim this study examine association between POP short birth intervals in a rural area Nepal. Methods A cross-sectional was conducted Panchapuri municipality, located Surkhet District Karnali Province questionnaire used collect information on POP, intervals, other known confounding...
Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes, also known as platelets, in the blood. Several medicinal plants possess curative and protective effect against thrombocytopenia associated with diseases or drugs.In present study, we have investigated platelet augmentation activity polyherbal formulation (VITA PLAT Capsule) cyclophosphamide-induced thrombocytopenic rat model.Twenty-four albino Wistar rats were divided into four groups. was induced...
Background. Meconium-stained amniotic fluid (MSAF) may reflect normal fetal gut maturation or indicate compromise. Protocols on the management of newborns with grade 3 MSAF exposure who do not require immediate resuscitation at birth, are required. Objectives. To determine outcomes born through MSAF. Methods. A retrospective chart review was conducted King Edward VIII Hospital (KEH) in Durban, KwaZulu-Natal (KZN), South Africa (SA) from 1 January to 31 December 2018. Data were collected 238...
This study investigates how lifestyle factors and westernization contribute to obesity examines the influence of body mass index (BMI) changes on "lipitension," a significant risk factor for heart disease metabolic syndrome.
Introduction Several studies have reported the usefulness of measuring lower limb muscle strength through motion standing up using a reaction force device positioned on ground. There is inadequate information association between cardiovascular disease risk factors and ground (GRF) during up. Therefore, this study estimated GRF by sit-to-stand movements in health check-up population. Methods This cross-sectional included 1,182 healthy participants without chronic diseases who underwent...
Influenza-associated pulmonary aspergillosis (IAPA) is a severe complication of influenza infection that occurs in critically ill patients and results higher mortality compared to alone. Interleukin-17 (IL-17) the Type 17 immune signaling pathway cytokine family are recognized for their pivotal role fostering protective immunity against various pathogens. In this study, we investigate IL-17 components during IAPA. Wild-type mice were challenged with A H1N1 (Flu) then exposed Aspergillus...
Effectiveness of video assisted teaching on knowledge regarding effects home accidents and its preventive measures among mother’s under five children selected in Bachwai Satna M.P Objectives: To assess the level M.P. Evaluate effectiveness find association between with their socio- demographic variables. Modified Kennys open system model was used. Quantitative approach True Experimental - pretest post test control group design 60 subjects were by simple random sampling., Pretest conducted...
Objective: The purpose of this study was to determine the effect birth weight discordance (BWD) and prematurity on twin neonatal outcome by measuring Apgar scores blood glucose concentrations at birth.
Background: Being underweight, overweight, or obese can lead to adverse health effects. Hence, it is important understand the specific factors that change burden of underweight and overweight target appropriate disease control strategies. This study was designed examine prevalence associated with among young middle-aged women in Japan. Materials Methods: A cross-sectional conducted aged 20–59 years who participated checkups at a regional care center 2018 2019 (N = 1722). The assessments...