A5101669697- Micro and Nano Robotics
- Advanced Sensor and Energy Harvesting Materials
- Advanced Materials and Mechanics
- Nanoplatforms for cancer theranostics
- Soft Robotics and Applications
- Nanoparticle-Based Drug Delivery
- Modular Robots and Swarm Intelligence
- Electrochemical Analysis and Applications
- Molecular Communication and Nanonetworks
- Tactile and Sensory Interactions
- Electrochemical sensors and biosensors
- 3D Printing in Biomedical Research
- Advanced biosensing and bioanalysis techniques
- Gas Sensing Nanomaterials and Sensors
- Graphene and Nanomaterials Applications
- Spaceflight effects on biology
- Electrohydrodynamics and Fluid Dynamics
- Analytical Chemistry and Sensors
- Microfluidic and Bio-sensing Technologies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Reliability and Maintenance Optimization
- Luminescence and Fluorescent Materials
- Electrowetting and Microfluidic Technologies
- Risk and Safety Analysis
- Autophagy in Disease and Therapy
Peking University
2025
Hubei Academy of Agricultural Sciences
2025
Tsinghua University
2025
University of Electronic Science and Technology of China
2024
Xiamen University
2022-2024
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2024
Huzhou University
2024
Hubei University
2024
Xi'an Jiaotong University
2020-2023
Southern Medical University
2017-2023
Developing untethered millirobots that can adapt to harsh environments with high locomotion efficiency is of interest for emerging applications in various industrial and biomedical settings. Despite recent success exploiting soft materials impart sophisticated functions which are not available conventional rigid robotics, it remains challenging achieve superior performances both wet dry conditions. Inspired by the flexible, soft, elastic leg/foot structures many living organisms, here we...
Micro/nanorobots have long been expected to reach all parts of the human body through blood vessels for medical treatment or surgery. However, in current stage, it is still challenging drive a microrobot viscous media at high speed and difficult observe shape position single once enters bloodstream. Here, we propose new micro-rocket robot an all-optic driving imaging system that can actuate track with microscale resolution. To achieve force, engineer rocket-like triple-tube structure. Owing...
Abstract The soft millirobot is a promising candidate for emerging applications in various in‐vivo/vitro biomedical settings. Despite recent success its design and actuation, the absence of sensing ability makes it still far from being reality. Here, radio frequency identification (RFID) based battery‐less that can move, sense, communicate remotely by coupling magnetic piezoelectric effects reported. This integrates robot actuation power generation units within thin multilayer film (<0.5...
Abstract Carbon‐based materials are widely used as light‐driven soft actuators relying on their thermal desorption or expansion. However, applying a passive layer in such film construction greatly limits the actuating efficiency, e.g., bending amplitude and speed. In this work, dual active strengthened bilayer composite made of graphene oxide (GO)–polydopamine (PDA)–gold nanoparticles (Au NPs)/polydimethylsiloxane (PDMS) is developed. film, conventional replaced by another AuNPs‐enhanced...
Abstract Tumor hypoxia is a major cause of failure in cancer therapy, and there almost no efficacious treatment for hypoxic tumors. Herein, an azo‐containing polymer (P2) designed to encapsulate IR1061, further covalently grafted with tumor‐targeting tripeptide RGD form P2@IR1061‐RGD NPs combined photothermal thermodynamic therapy (PTT/TDT) the near‐infrared II (NIR II) biowindow (1000–1700 nm). Upon 1064 nm laser irradiation, IR1061 generates heat break azo bonds P2, achieving robust carbon...
Electrodynamic therapy (EDT) combining nanotechnology with electronic current was used in this study to generate highly cytotoxic oxidative hydroxyl radicals (·OH) for tumor destruction. However, increasing evidence suggests that EDT treatment alone one time still faces great challenges achieving long-term suppression an immunosuppressive environment, which would raise the risk of later recurrence. Benefitting from marvelous potential reactive oxygen species (ROS)-mediated dynamic therapies...
Chemoresistance is a formidable issue in clinical anticancer therapy and pertinent to the lowered efficacies of chemotherapeutics activated tumor self-repairing proceedings. Herein, bifunctional amphiphiles containing galactose ligands high-density disulfide are synthesized for encapsulating mitochondrion-targeting tetravalent platinum prodrugs construct cascade targeted mitochondrion-dysfunctional nanomedicine (Gal-NP@TPt). Subsequent investigations verify that Gal-NP@TPt with sequential...
To explore the intergenerational cardiotoxicity of nanoplastics, maternal mice were exposed to 60 nm polystyrene nanoplastics (PS-NP) during pregnancy and lactation. The results showed that PS-NP can enter hearts offspring induce myocardial fiber arrangement disorder, acidophilic degeneration cardiomyocytes, elevated creatine kinase isoenzymes (CK-MB) lactate dehydrogenase (LDH) levels after exposure at 100 mg/kg Mechanistically, KEGG analysis RNA sequencing participation hypoxia-inducible...
Abstract As a kind of reptile that can move in sophisticated environment by periodic changes body shape, snake's locomotion mode has inspired the design several novel robots. Yet, most those conventional robots are constructed rigid components and powered electricity. Herein, snake‐inspired soft robot fabricating triple‐layer reduced graphene oxide polydopamine is reported. Such material capable bidirectional deformation while near‐infrared (NIR) light projected at different regions. It...
Abstract Developing novel photosensitizers for deep tissue imaging and efficient photodynamic therapy (PDT) remains a challenge because of the poor water solubility, low reactive oxygen species (ROS) generation efficiency, serve dark cytotoxicity, weak absorption in NIR region conventional photosensitizers. Herein, cyclometalated iridium (III) complexes (Ir) with aggregation-induced emission (AIE) feature, high photoinduced ROS two-photon excitation, mitochondria-targeting capability were...
Abstract Recently, the optical field driving mechanism is emerging in manipulation of small‐scale soft robots due to its remote, wireless, and selective control capabilities. Among light‐responsive materials, carbon has exhibited great potentials as light‐driven actuators good light absorption ability, thermal conductivity, mechanical strength. Taking advantage various carbon‐based are reported with efficient, fast response, stable actuating performance. Hence, widely applied robotic...
Abstract Plant species like the Venus flytrap possess unique abilities to intelligently respond various external stimuli, ensuring successful prey capture. Their nerve-devoided structure provides valuable insights for exploring natural intelligence and constructing intelligent systems solely from materials, but limited knowledge is currently available engineering realization of such concept remains a significant challenge. Drawing upon flytrap’s action potential resulting ion diffusion, we...
SUMMARY Anthocyanins, the important antioxidants and signaling molecules, are natural polyphenolic compounds widely present in plants essential for plant defense. However, little is known about mechanisms underlying anthocyanin accumulation relation to drought stress. This study reveals that stress induces significant Rosa chinensis , alongside an increase expression of MYB transcription factor (TF) gene RcMYB75 glutathione S‐transferase (GST) RcGSTFL11 . When overexpressed, markedly...
The functionalization of microrobots is essential for realizing their biomedical application in targeted cargo delivery, but the multifunctional integration and controllable delivery remains an enormous challenge at present. This work reports a kind multi-functionalized micro-helical robot with superior loading capabilities controlled release encapsulants. magnetic microrobot, multilayer capsule helical structure, was developed via strategies, including microfluidic synthesis,...
A serrated tail with multiple channels and nanointerfaces is used for the first time in a 3D swimming microrobot to enhance chemical reaction interfaces realize powerful high-speed motion.
Lead (Pb) pollution is an important environmental and public health concern. Rapid Pb transport during stormwater runoff significantly impairs surface water quality. The ability to characterize model these events critical mitigating its impact on the environment. However, analysis limited by lack of analytical methods that can afford rapid, sensitive measurements in situ. While electrochemical have previously shown promise for rapid analysis, they are currently two ways. First, because Pb's...
In the robot-aided biomedical field, although cell pierce force may be decreased by sharpening injection needle and robotic control, physical damage to remains a big issue for low-invasive injection. This article proposes 7-DoFs rotation-thrust (R-T) microrobotic control instead of conventional straightforward thrust smaller penetrated deformation higher stability, thus decreasing cell. Considering fully, beneficial resultant shear as well axial based on point-load model, dynamic centering...