About
Contact & Profiles
A5072031174
Research Areas
- Cardiac Fibrosis and Remodeling
- Traumatic Brain Injury and Neurovascular Disturbances
- Signaling Pathways in Disease
- CRISPR and Genetic Engineering
- Protease and Inhibitor Mechanisms
- Climate Change and Health Impacts
- Cell Adhesion Molecules Research
- Energy and Environment Impacts
- RNA Interference and Gene Delivery
- Air Quality and Health Impacts
- Angiogenesis and VEGF in Cancer
- Pluripotent Stem Cells Research
- Neurological Disease Mechanisms and Treatments
Second Affiliated Hospital of Zhejiang University
2021-2025
University of California, Los Angeles
2021-2023
Despite the prevalence of pericytes in microvasculature heart, their role during ischemia-induced remodeling remains unclear. We used multiple lineage-tracing mouse models and found that migrated to injury site expressed profibrotic genes, coinciding with increased vessel leakage after myocardial infarction (MI). Single-cell RNA-Seq cardiac at various time points MI revealed temporally regulated induction genes related vascular permeability, extracellular matrix production, basement membrane...
10.1172/jci162188
article
EN
cc-by
Journal of Clinical Investigation
2023-05-15
10.1038/s44161-025-00617-1
article
EN
Nature Cardiovascular Research
2025-03-27
10.1016/j.envres.2023.117678
article
EN
Environmental Research
2023-11-19
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