"Correlation between Histopathology, Immune Response, Clinical Presentation, and Evolution in Leishmania braziliensis Infection" published on Sep 1991 by The American Society of Tropical Medicine Hygiene.

Journal Article The Relationship of Leishmania braziliensis Subspecies and Immune Response to Disease Expression in New World Leishmaniasis Get access Nancy Gore Saravia, Saravia Please address requests for reprints G. CIDEIM, Apartado Aéreo 5390, Cali, Colombia, South America. Search other works by this author on: Oxford Academic PubMed Google Scholar Liliana Valderrama, Valderrama Maricel Labrada, Labrada Ana Fernanda Holguin, Holguin Claudia Navas, Navas Gloria Palma, Palma Kristen A....

Onchocerciasis is a chronic parasitic infection originally endemic in 13 discrete regional foci distributed among six countries of Latin America (Brazil, Colombia, Ecuador, Guatemala, Mexico and Venezuela). In this disease was discovered 1965 the Pacific Coast country. The National Elimination Program established 1993 with aim eliminating morbidity transmission. 2013, World Health Organization (WHO) verified Colombia as free onchocerciasis, becoming first country world to reach such goal....

In order to determine the frequency of therapeutic failures chloroquine (CQ) in patients with malaria due either Plasmodium falciparum or P. vivax, and explore usefulness a malaria-free city as sentinel site monitor emergence drug resistance, 53 (44 infected vivax 9 falciparum) were evaluated at Laboratory Parasitology, Universidad del Valle Cali, Colombia. Patients received 25 mg/kg CQ divided three doses over 48 h; they followed during 28 days according WHO/PAHO protocols. While group not...

Verifying the compliance with ethical principles of health research legitimizes its exercise in eyes society and allows for resolution dilemmas that emerge from new interests methods. Resolution 8430 1993 is one main guidelines governing on human beings Colombia. Considering has not been revised or updated since promulgation it becomes necessary to evaluate current validity adequacy address potential existing country’s research. Some gaps, contradictions, aspects require a deep review are...

Alternative, non-microscopic methods for the diagnosis of malaria have recently become available. Among these, rapid dipstick stand out. One such test, OptiMAL®, is based on immunochromatographic detection Plasmodium lactate dehydrogenase (pLDH) and has capacity to detect distinguish infections caused by P. falciparum sp. This particularly important in countries where different species co-exist. In this study we evaluated performance OptiMAL® an urban referral center diagnosis. Two sets...

"Filariasis in Colombia: Prevalence and Distribution of Mansonella Ozzardi (=Dipetalonema) Perstans Infections the Comisaría Del Guainía" published on Mar 1983 by The American Society Tropical Medicine Hygiene.

Introduction. The Montenegro skin test reaction and leishmaniasis lesions share fundamental characteristics of a delayed type hypersensitivity reaction.Objectives. To determine whether the (response to leishmanin) might approximate thereby provide insight into early inflammatory immune response Leishmania infection.Materials methods. We compared in biopsies acute (evolution time £one month), chronic ³6 months) with corresponding patients, asymptomatically infected volunteers.Results....

Both host and parasite determinants influence the outcome of Leishmania infections. Human responses in cutaneous leishmaniasis limited duration caused by a single species Viannia (V) subgenus were studied skin biopsies obtained from lesions panamensis 31 male patients Colombian Pacific Coast. Dermal infiltrates histopathologic changes characterized using monoclonal antibodies an indirect immunoperoxidase method. distribution T-cell subpopulations B-lymphocytes was nonrandom: CD4+ CD8+ T...

The existence of an intracellular stage Trypanosoma rangeli in the vertebrate host was evaluated by experimental infection U937 histiocytic cell line with San Agustín strain and Ub66-5b clone. identity parasites at beginning end experiments confirmed through biological behavior vector mammal hosts, isoenzymes, polymerase chain reaction (PCR), monoclonal antibodies. Infectivity to cells T. obtained from culture salivary glands under different conditions. These included 34 C vs. 37 C,...

Con el objeto de aumentar la sensibilidad del diagnóstico histopatológico lesiones cutáneas y mucocutáneas causada por subespecies complejo Leismania braziliensis para lograr una mejor visualización los parásitos en las lesiones, se evaluó método inmunoperoxidas indirecta localizar forma rápida específica amastigotas biopsia tejido afectado. Los cortes fijaron formol incluyeron parafina; después evaluaron inmunohistoquímica usando un antisuero policlonal producido conejo, como reactivo...

We evaluated the importance of neutrophils in development chronic lesions caused by L. Viannia spp. using hamster as experimental model American Cutaneous Leishmaniasis (ACL). Neutrophils infiltrated lesion within first six hours post-infection. Inhibition this early infiltration a polyclonal antibody or cyclophosphamide was associated with transient parasite control but protective effect vanished when became clinically apparent. At onset (approximately 10 days p.i.), there an increased...

"Filariasis in Colombia: Prevalence of Mansonella Ozzardi the Departamento de Meta, Intendencia Del Casanare, and Comisaría Vichada" published on Jan 1984 by The American Society Tropical Medicine Hygiene.

To assess the current epidemiologic status of onchocerciasis in Colombia two surveys were undertaken 1995 a suspected new focus on border between and Ecuador known located Micay River. No was found along Colombia-Ecuador border. In focus, communities upper River its tributaries surveyed; 655 adults underwent physical examinations skin biopsies. Infected individuals almost exclusively community Naiciona, where prevalence infection 40% (36 91). Polymerase chain reaction detection onchocercal...

Introduction. Ethics committees are a necessary resource to guarantee ethical integrity in human research; they must apply international standards their evaluation of research projects involving subjects.Objective. The ethics for Colombia were characterized, and recommendations strengthening them formulated.Materials And Methods. In 2003, 280 groups with subjects selected from list which form part the science technology network Colciencias. (Colciencias is Colombian national agency that...

Durante tres años (1990-1993), la aplicación del método ecoepidemiológico en el foco de leishmániosis visceral Costa Caribe co­lombiana permitió comprender mecanismo transmisión enfermedad, demostrán­dose un nuevo vector leishmaniosis ame­ricana: Lutzomyia evansi como princi­pal esta región. Leishmania infantum (=L. chagasi) es responsable tanto algunos casos cutánea; se encuentra igualmente a L. braziliensis ocasionando lesiones cutá­neas. El opposum o zarigüeya (Didelphis marsupiales)...

Onchocerciasis, also known as River Blindness, is a parasitic disease caused by the nematode Onchocerca volvulus and transmitted black flies of genus Simulium. It endemic in Africa, where an estimated 37 million people are infected. almost certain that slave trade 17th 18th centuries brought onchocerciasis from West Africa to Americas (1), transmission foci established six countries: Mexico, Guatemala, Venezuela, Brazil, Ecuador Colombia. Since beginning 20th century it was suspected this...

En 1965 se describió el primer foco de oncocercosis humana en Colombia López Micay, la costa pacífica.Doce años después, una visita seguimiento mostró que prevalencia infección había disminuido del 15 al 7,5%.Ya no volvieron a reportar pacientes, consideró extinguido hasta 1989, cuando un niño con queratitis ocular fue remitido Hospital Universitario Cali.Se confirmó diagnóstico biopsia piel.En julio 1989 hizo nueva área y tomaron muestras 170 personas.La detectada por piel 4,1% (71170).Se...