A5101978195- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
- Cardiac, Anesthesia and Surgical Outcomes
- Thyroid Disorders and Treatments
- S100 Proteins and Annexins
- Photoacoustic and Ultrasonic Imaging
- Genetic factors in colorectal cancer
- Biomarkers in Disease Mechanisms
- Pancreatic and Hepatic Oncology Research
- Salivary Gland Tumors Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Spine and Intervertebral Disc Pathology
- Cancer-related Molecular Pathways
- Electrospun Nanofibers in Biomedical Applications
- Musculoskeletal pain and rehabilitation
- Cancer Cells and Metastasis
- Advanced X-ray and CT Imaging
- BRCA gene mutations in cancer
- Pituitary Gland Disorders and Treatments
- Medical and Biological Sciences
- Anesthesia and Pain Management
- Immunotherapy and Immune Responses
Catholic University of Korea
2015-2025
Korea University
2024
Statistics Korea
2024
Seoul St. Mary's Hospital
2013-2023
Incheon National University
2020-2023
Inha University Hospital
2022
Chung-Ang University
2022
Auckland University of Technology
2022
University of Victoria
2022
Brandeis University
2022
To confirm the merits of robotic thyroid surgery by comparing surgical outcomes robotic-assisted and conventional endoscopic thyroidectomy in papillary microcarcinoma (PTMC) patients.Robot-assisted techniques are widely utilized, substantially, overcome limitations surgery. Furthermore, recently, procedures were introduced to field.From November 2001 July 2009, 1150 patients with PTMC underwent using a gasless, trans-axillary approach. Of these patients, 580 procedure (the group; RG) 570...
Abstract Central nervous system (CNS)-infiltrating effector T cells play critical roles in the development and progression of multiple sclerosis (MS). However, current drugs for MS are very limited due to difficulty delivering into CNS. Here we identify a cell-permeable peptide, dNP2, which efficiently delivers proteins mouse human cells, as well various tissues. Moreover, it enters brain tissue resident through blood vessels by penetrating tightly organized blood–brain barrier. The...
Chronic stress disrupts brain homeostasis and adversely affects the cerebro-vascular system. Even though effects of chronic on system have been extensively studied, there are few in vivo dynamic studies In this study, cerebral vasculature BBB permeability were studied using two-photon (2p) microscopic imaging with an injection fluorescence-conjugated dextran. Our real-time 2p results showed that reduced vessel diameter reconstructed vascular volume, regardless type branching order. was...
The tall cell variant of papillary thyroid carcinoma (TCVPTC) is more aggressive than classic (PTC), but the percentage cells needed to diagnose TCVPTC remains controversial. In addition, little known about clinicopathologic features PTC with (TCF).We retrospectively selected and reviewed presence BRAF mutation in 203 cases PTC, 149 TCF, 95 TCVPTCs, which were defined as PTCs having <10%, 10-50%, ≥50% cells, respectively.TCVPTCs TCF did not vary significantly characteristics such pathologic...
Background . The Warthin-like variant of papillary thyroid (WLPTC) is a rare subtype carcinoma (PTC) resembling Warthin tumors the salivary glands. Due to its rarity, clinicopathologic and molecular features WLPTC remain unclear. Methods Of 2,139 patients who underwent surgical treatment for PTC from 2012 2013, 40 with were identified compared 200 consecutive classic PTC. BRAF mutation was tested pyrosequencing. Results There no significant differences in age, predilection women,...
Background: Although most differentiated thyroid carcinomas (DTCs) have indolent behavior, DTCs with distant metastasis a poor prognosis. However, there are no validated markers that predict the risk of and prognosis DTC. We aimed to develop genetic classifier for predicting outcomes DTC patients metastases. Methods: Targeted deep sequencing 157 cancer-related genes was performed 61 A candidate mutation independent cancer samples using digital polymerase chain reaction. Results: The...
Clinicopathological Features of Rare BRAF Mutations in Korean Thyroid Cancer PatientsThe most common mutation thyroid cancer is c.1799T > A (p.Val600Glu), and other mutations are rarely reported.We investigated the clinicopathological features with rare mutations.A total 2,763 patients underwent molecular testing by direct DNA sequencing for exon 15.Among them, 2,110 (76.4%) had mutations.The was found 2,093 (76.9%) 2,722 papillary carcinomas one 7 medullary carcinomas.Sixteen cases (0.76%)...
Abstract Purpose: Traditional methods, fine-needle aspiration cytology (FNAC) and washout thyroglobulin (Tg), do not always provide sufficient accuracy for diagnosing lymph node (LN) metastasis in thyroid cancer. This study aimed to validate the diagnostic performance of cytokeratin fragment 21-1 (CYFRA 21-1) as a complementary biomarker metastatic LNs cancer explore its relationship with molecular analysis distant metastasis. Patients Methods: In this retrospective cohort involving 230 224...
<div>AbstractPurpose:<p>Traditional methods, fine-needle aspiration cytology (FNAC), and washout thyroglobulin (Tg) do not always provide sufficient accuracy for diagnosing lymph node (LN) metastasis in thyroid cancer. This study aimed to validate the diagnostic performance of cytokeratin fragment 21-1 (CYFRA 21-1) as a complementary biomarker metastatic LN cancer explore its relationship with molecular analysis distant metastasis.</p>Experimental Design:<p>In this...
Background. Most patients with a preoperative diagnosis of thyroid follicular neoplasm (FN) undergo diagnostic surgery to determine whether the nodule is benign or malignant. Point mutations at NRAS codon 61 are most common observed in FN. However, clinical significance mutation remains unclear. Methods. From 2012 2013, 123 consecutive undergoing thyroidectomy for FN were evaluated prospectively. Molecular analyses performed pyrosequencing. Results. The overall malignancy rate was 48.8%...
Summary Context The coexistence of differentiated thyroid cancer ( DTC ) and autoimmune disease could represent a better or worse prognosis. This study investigated the prognostic importance preoperative anti‐thyroglobulin antibody (TgAb) in patients. Design patients retrospective hospital‐cohort enrolled 1171 consecutive with TgAb data, who underwent total thyroidectomy between January 2006 December 2011. Clinical parameters studied included demographics, primary tumour characteristics,...