A5008697972- Bee Products Chemical Analysis
- Essential Oils and Antimicrobial Activity
- Insect and Pesticide Research
- Phytochemicals and Antioxidant Activities
- Marine Sponges and Natural Products
- Phytochemistry Medicinal Plant Applications
- Fermentation and Sensory Analysis
- Fungal Biology and Applications
- Pharmaceutical and Antibiotic Environmental Impacts
- Spectroscopy and Chemometric Analyses
- Horticultural and Viticultural Research
- Advanced Glycation End Products research
- Phytochemistry and Bioactivity Studies
- Synthesis and Biological Activity
- Agricultural and Food Sciences
- Phytochemistry and Biological Activities
- Microbial Natural Products and Biosynthesis
- Analytical chemistry methods development
- Analytical Chemistry and Chromatography
- Heavy Metals in Plants
- Plant and animal studies
- Geochemistry and Geologic Mapping
- Aquaculture Nutrition and Growth
- Insect and Arachnid Ecology and Behavior
- Pesticide Residue Analysis and Safety
Universidade Estadual do Centro-Oeste
2015-2024
Midwestern State University
2016
Universidade de São Paulo
2000-2009
Universidade Federal de São Carlos
2000-2004
Universidade Federal do Paraná
2002
Universidade Federal do Rio de Janeiro
2000
The chemical composition and biological activity of a sample yellow propolis from Mato Grosso do Sul, Brazil (EEP-Y MS), were investigated for the first time compared with green, brown, red types Brazilian Cuba. Overall, EEP-Y MS had different qualitative profiles, as well cytotoxic antimicrobial activities when to other assessed in this study it is chemotype propolis. Absence phenolic compounds presence mixtures aliphatic determined by analysing (1)H-NMR spectra fifteen terpenes identified...
EXTRACT: AN ALTERNATIVE TO ETHANOLIC EXTRACT.Propolis is mostly used as hydroalcoholic extract.Recently there has been a growing number of patents dealing with new solvents for preparing propolis extracts.This study aimed to prepare edible oil extracts and compare their chemical composition biological activity ethanolic extracts.ESI-MS spectrophotometric methods were qualitative quantitative analyses, respectively.Antibacterial was evaluated by diffusion in agar.Cytotoxicity tested MTT assay...
Objective . As propolis is a highly valued bee product, we aimed to verify the quality of aged propolis, investigating their phenolic and flavonoid composition, levels toxic metals, radical scavenging antimicrobial activities. Material Methods Samples fresh six different beekeepers, from same geographical location, were investigated in terms composition Pb, Cd, Cr, as well Results The two groups had similar qualitative by HPLC-PDA ESI(-)-MS. Fresh show no differences when average values...
Fractionation of the crude methanol extract ascidian Cystodytes dellechiajei collected in Brazil yielded two novel alkaloids, sebastianine A (1) and B (2). The structures both 1 2 were established by analysis spectroscopic data, indicating an unprecedented ring system for compounds, comprising a pyridoacridine fused with pyrrole unit pyrrolidine condensed α-hydroxyisovaleric acid Both alkaloids displayed cytotoxic profile against panel HCT-116 colon carcinoma cells indicative p53 dependent mechanism.
Tithonia diversifolia is a perennial bushy plant found in South America with significant ethnopharmacological importance as an antimalarial, antidiabetic, antibacterial, and anticancer agent. The aim of the present study was to determine cytotoxicity ethanolic extract from leaves T. (TdE) on human cancer cell lines (HCT-116, SNB-19, NCIH-460 MCF-7), well mechanism action involved death cellular modulation oxidative stress. TdE exhibited activity IC50 values ranging 7.12 38.41 μg/ml, HCT-116...
Propolis biological effects are mainly attributed to its polyphenolic constituents such as flavonoids and phenolic acids that were recently described in the chemical composition of an extract propolis obtained with edible vegetal oil (OEP) by our group. The aim this study was evaluate effect OEP on behavior rats.An vivo open field (OF), elevated Plus-maze (EPM), forced swimming (FS) tests performed locomotor activity, anxiolytic- antidepressant extract. Besides, oxidative stress levels...
Arenosclerins A (2), B (3), and C (4), as well haliclonacyclamine E (1), are new tetracyclic alkylpiperidine alkaloids isolated from a species of marine sponge belonging to the order Haplosclerida, Arenosclera brasiliensis, endemic southeastern Brazilian coast. The were their hydrochloride salts identified by analysis spectroscopic data. Data obtained (1)H-(1)H COSY, HMBC, HSQC-TOCSY NMR experiments allowed complete assignment (1)H (13)C resonances, NOESY ROESY spectra showed that only...
Propolis is a resin produced by bees from raw material collected plants, salivary secretions, and beeswax. New therapeutic properties for the Central Nervous System have emerged. We explored neurobehavioral antioxidant effects of an ethanolic extract yellow propolis (EEYP) rich in triterpenoids, primarily lupeol β ‐amyrin. Male Wistar rats, 3 months old, were intraperitoneally treated with Tween 5% (control), EEYP (1, 3, 10, 30 mg/kg), or diazepam, fluoxetine, caffeine (positive controls)...
ASCIDIAN Didemnum ligulum AND FROM THE OCTOCORAL Carijoa riisei.The investigation of extracts from six species marine invertebrates yielded one new and several known natural products.Isoptilocaulin the sponge Monanchora aff.arbuscula displayed antimicrobial activity at 1.3 μg/mL against an oxacillin-resistant strain Staphylococcus aureus.Five inactive dibromotyrosine derivatives, 2 -6, were isolated a sponge, Aplysina sp.The sponges Petromica ciocalyptoides Topsentia ophiraphidites...
The chemical investigation of the crude extract an ascidian genus Didemnumled to isolation modified diketopiperazine rodriguesines A (1) and (2) as a mixture homologues, which could be identified by analysis spectroscopic data including MS/MS experiments. second Didemnumsp. led N-acetyl-rodriguesine (3) B (4). absolute configuration compounds 1and 2could established hydrolysis Marfey's comparison with literature reported for compound 3, previously obtained synthetic product. 2displayed...