A5043560800- Pesticide Residue Analysis and Safety
- Pharmacological Effects and Assays
- Antibiotics Pharmacokinetics and Efficacy
- Antioxidant Activity and Oxidative Stress
- Analytical Chemistry and Chromatography
- Toxic Organic Pollutants Impact
- Pharmaceutical and Antibiotic Environmental Impacts
- Per- and polyfluoroalkyl substances research
- Metabolomics and Mass Spectrometry Studies
- Edible Oils Quality and Analysis
- Environmental Toxicology and Ecotoxicology
- Insect and Pesticide Research
- Free Radicals and Antioxidants
- Phytochemicals and Antioxidant Activities
- Analytical Methods in Pharmaceuticals
- Coccidia and coccidiosis research
- Mercury impact and mitigation studies
- Veterinary Pharmacology and Anesthesia
- Essential Oils and Antimicrobial Activity
- Effects and risks of endocrine disrupting chemicals
- Atmospheric chemistry and aerosols
- Antifungal resistance and susceptibility
- Eicosanoids and Hypertension Pharmacology
- Bee Products Chemical Analysis
- Advanced Chemical Sensor Technologies
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche
2016-2025
University of Urbino
1992-1996
University of Bologna
1990-1995
A study was carried out to determine the quality characteristics, antioxidant capacity, oxidative status, and consumer acceptability of chicken meat after dietary administration a semi-solid olive cake, known as “paté” (pOC), in broilers. pOC is an oil industry waste rich bioactive compounds, such polyphenols, obtained by mechanical extraction from destoned olives. Two hundred ninety-seven 22-day-old fast growing (Ross 308) female chicks were randomly assigned three experimental...
Abstract Two recent randomized controlled trials demonstrated improved radiographic, histological and hepatometabolic cues of non-alcoholic steatohepatitis (NASH) in pediatric patients treated with the ω-3 fatty acid docosahexaenoic (DHA) combination vitamin D (VD) or choline (CHO) E (VE), DHA-VD DHA-CHO-VE trials, respectively). In present study we verified nutritional compliance to these DHA-based multivitamin treatments; lipidomics biomarkers reported outcome on NASH indicators were also...
Abstract Tryptophan catabolism is a major metabolic pathway utilized by several professional and non-professional antigen presenting cells to maintain immunological tolerance. Here we report that 3-hydroxy- l -kynurenamine (3-HKA) biogenic amine produced via an alternative of tryptophan metabolism. In vitro, 3-HKA has anti-inflammatory profile inhibiting the IFN-γ mediated STAT1/NF-κΒ in both mouse human dendritic (DCs) with consequent decrease release pro-inflammatory chemokines cytokines,...
In the last few years, different formulations containing cannabidiol (CBD) were tested with regard to its efficacy on chronic pain, refractory epilepsy, anxiety, aggressive behavior and atopic dermatitis in dogs. CBD is generally administered orally, but low bioavailability, probably due a first-pass metabolism, represents great limitation. The aim of this study was evaluate if bioavailability increases after oral transmucosal administration (OTM) compared treatment.Twelve dogs diagnosed...
The metabolism of α-tocopherol (α-TOH, vitamin E) shows marked interindividual variability, which may influence the response to nutritional and therapeutic interventions with this vitamin. Recently, new metabolomics protocols have fostered possibility explore such variability for different metabolites α-TOH so far identified in human blood, i.e., “vitamin E metabolome”, some been reported promote important biological functions. Such advances prompt definition reference values degree these at...
Pain management in horses plays a pivotal role the therapeutic approach to several diseases. Horses have cannabinoid receptors at level of dorsal root ganglia, blood vessels, and synoviocytes that can be up or down- regulated by inflammatory conditions, justifying possible efficacy exogenous cannabinoids (i.e., phytocannabinoids) managing painful pathologies this animal species. However, current use supplements containing cannabidiol (CBD) equines is based on anecdotal evidence, without...
Listeria monocytogenes (LM) is a frequent post-process contaminant in meat products. This study aimed to investigate the antilisterial effectiveness of antimicrobial treatments employing olive mill wastewater polyphenolic extract (PE) commercially manufactured frankfurters. Frankfurters were inoculated on surface with three-strain LM mixture (~102 CFU/g), treated PE 2-fold series concentrations (PM, 2PM, 4PM) and control group (CTR) PE-untreated samples. Then, frankfurters vacuum-packed...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereoselective synthesis of 3-(ethoxycarbonyl)-4-hydroxy-5-(1-hydroxyalkyl)-2-isoxazoline 2-oxides by reaction 2,3-epoxy aldehydes and ethyl nitroacetate on alumina surfaceGoffredo Rosini, Roberta Galarini, Emanuela Marotta, Paolo RighiCite this: J. Org. Chem. 1990, 55, 3, 781–783Publication Date (Print):February 1, 1990Publication History Published online1 May 2002Published inissue 1 February...
A multiclass method for screening and confirmatory analysis of antimicrobial residues in milk has been developed validated. Sixty-two antibiotics belonging to ten different drug families (amphenicols, cephalosporins, lincosamides, macrolides, penicillin, pleuromutilins, quinolones, rifamycins, sulfonamides tetracyclines) have included. After the addition an aqueous solution EDTA, samples were extracted twice with acetonitrile, evaporated dissolved ammonium acetate. centrifugation, 10 µl...
A multiple heart-cutting (mLC-LC) two-dimensional HPLC-UV achiral–chiral method for the direct analysis of branched-chain amino acids (BCAAs) in food supplements under environmentally friendly conditions was developed to cope with very well-known limited chemoselectivity chromatographic media enantioselective analysis. Both achiral and chiral methods were compliance main principles green chromatography. The performed isocratically an optimized ion-pair reversed-phase (IP-RP) based on a...
Potato sprouts, an underutilized by-product of potato processing, could be exploited for the recovery caffeoyl-quinic acids (CQAs), a family polyphenols with well-recognized biological activities. In this work, predominant compound class, 5-CQA, was extracted by Ultrasound-Assisted Extraction (UAE) under conditions optimized Experimental Design. The investigated variables solid/solvent ratio (1:10–1:50 g/mL), water content in ethanol (30–100% v/v) and UAE time (5–20 min) highlighted critical...