A5053728592- Pleistocene-Era Hominins and Archaeology
- Forensic and Genetic Research
- Forensic Anthropology and Bioarchaeology Studies
- Genomics and Phylogenetic Studies
- Telomeres, Telomerase, and Senescence
- Fermentation and Sensory Analysis
- HIV Research and Treatment
- Genetics, Bioinformatics, and Biomedical Research
- Archaeology and ancient environmental studies
- Fungal Biology and Applications
- Wildlife Ecology and Conservation
- Animal Behavior and Reproduction
- Aquaculture disease management and microbiota
- Genomic variations and chromosomal abnormalities
- Genomics and Chromatin Dynamics
- Race, Genetics, and Society
- Animal Diversity and Health Studies
- Immune cells in cancer
- Mycorrhizal Fungi and Plant Interactions
- Advanced biosensing and bioanalysis techniques
- interferon and immune responses
Université Paris-Saclay
2021
Écologie, Systématique et Évolution
2021
Centre National de la Recherche Scientifique
2021
AgroParisTech
2021
University at Buffalo, State University of New York
2017-2020
State University of New York
2018
Buffalo BioLabs
2018
Bridge University
2017
One of the most abundant proteins in human saliva, mucin-7, is encoded by MUC7 gene, which harbors copy number variable subexonic repeats (PTS-repeats) that affect size and glycosylation potential this protein. We recently documented adaptive evolution variation among primates. Yet, genetic humans remained unexplored. Here, we found PTS-repeat has evolved recurrently lineage, thereby generating multiple haplotypic backgrounds carrying five or six alleles. Contrary to previous studies, no...
In heterothallic basidiomycete fungi, sexual compatibility is restricted by mating types, typically controlled two loci: PR, encoding pheromone precursors and receptors, HD, types of homeodomain transcription factors. We analysed the single mating-type locus commercial button mushroom variety, Agaricus bisporus var. bisporus, related variety burnettii. identified location using genetic map genome information, corresponding to HD locus, PR having lost its role. found mip1 β-fg genes flanking...
The time, extent, and genomic effect of the introgressions from archaic humans into ancestors extant human populations remain some most exciting venues population genetics research in past decade. Several studies have shown population-specific signatures introgression events Neanderthals, Denisovans, potentially other unknown hominin different groups. Moreover, it was that these may contributed to phenotypic variation humans, with biomedical evolutionary consequences. In this study, we...
CD36 was identified as a core replicative senescence gene and potential mediator of this process through membrane remodeling.
Neanderthals contributed genetic material to modern humans via multiple admixture events. Initial events presumably occurred in Western Asia shortly after migrated out of Africa. Despite being a focal point admixture, earlier studies indicate lower Neanderthal introgression rates some Asian populations as compared with other Eurasian populations. To better understand the genome-wide and phenotypic impact region, we sequenced whole genomes nine present-day Europeans, Africans, Druze at high...
Western Asia lies at the heart of Old World, in midst Africa, Asia, and Europe. As such, this region has been populated repopulated by myriad peoples, starting with first migrants from Africa. All evidence points to for beginnings sedentary life, indeed, villages later cities land remain as archaeological wonders, revealing complex histories multiple peoples their interactions. With wondrous breakthroughs genomic studies, we now have power look these a truly quantitative lens. Here, review...
Summary Cellular senescence, the irreversible ceasing of cell division, has been associated with organismal aging, prevention cancerogenesis, and developmental processes. As such, evolutionary basis biological features cellular senescence remain a fascinating area research. In this study, we conducted comparative RNAseq experiments to detect genes replicative in two different human lines at time points. We identified 841 900 (core senescence-associated genes) that are significantly up-...