Longjun Ma

ORCID: 0000-0003-1607-3362
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Research Areas
  • Sulfur-Based Synthesis Techniques
  • Synthesis and Catalytic Reactions
  • Chemical Synthesis and Reactions
  • Bioactive Compounds and Antitumor Agents
  • Lung Cancer Research Studies
  • Cancer therapeutics and mechanisms
  • Electrocatalysts for Energy Conversion
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Catalytic Processes in Materials Science
  • Prostate Cancer Treatment and Research
  • Viral Infections and Vectors
  • MicroRNA in disease regulation
  • Radiopharmaceutical Chemistry and Applications
  • Catalysts for Methane Reforming
  • Asymmetric Synthesis and Catalysis
  • Radical Photochemical Reactions
  • Catalytic C–H Functionalization Methods
  • Catalysis and Oxidation Reactions
  • Estrogen and related hormone effects
  • Extracellular vesicles in disease

Lanzhou Jiaotong University
2022-2025

Nanjing Medical University
2025

East China Normal University
2015-2022

Chinese Academy of Sciences
2018-2019

Chengdu Institute of Biology
2019

Chengdu Organic Chemicals (China)
2018

University of Chinese Academy of Sciences
2018

Herein, we describe an example of catalytic asymmetric synthesis sulfinamides. Aromatic sulfenamides were chosen as useful substrates, because the indispensable N–H bond, which could form efficient hydrogen bond with chiral phosphoric acid. H2O2 (35%) was used terminal oxidant for preparation sulfinamides in high yields and enantioselectivities, be easily derivatized to sulfoxides other without loss enantioselectivity.

10.1021/acscatal.8b04850 article EN ACS Catalysis 2019-01-22

10.1016/j.ejmech.2016.03.063 article EN European Journal of Medicinal Chemistry 2016-03-24

Artemisia capillaris, a traditional medicinal plant, is renowned for its therapeutic properties, including the promotion of anti-inflammatory and bile secretion. Notably, it has demonstrated efficacy in treatment jaundice. This study aimed to evaluate potential capillaris-derived exosomes (ACDEs) as novel approach non-alcoholic fatty liver disease (NAFLD). The physicochemical properties ACDEs were isolated characterized using differential centrifugation, was evaluated an vivo...

10.3389/fphar.2024.1476820 article EN cc-by Frontiers in Pharmacology 2025-01-06

Sulfonimidamides, featuring a hexavalent sulfur structure, are class of key compounds with broad application prospects in the fields pharmaceuticals and agrochemicals. However, their applications have been limited due to lack economically effective synthetic methods. Utilizing cost-effective readily accessible sulfonyl chloride as initial reagent, this method involves sequential formation intermediates, including sulfinamide sulfonimidoyl chloride, culminating synthesis sulfonylimidamide...

10.1055/a-2552-5688 article EN Synlett 2025-03-06

Abstract 1-Phenyl-3-azaarenyl-propan-1-amine structural moieties have been widely incorporated in pharmaceuticals and biologically active compounds; however, current synthetic methods to access these compounds need multiple steps proceed with low efficiency. Herein, we reported an efficient photocatalytic carbamoyl radical transfer approach that allows the preparation of high yields (up 88%). The reaction easily runs on a gram-scale was applied for pheniramine two 72% total yield.

10.1055/a-2256-3096 article EN Synlett 2024-01-29

Abstract Although the power of chiral sulfinamide reagents in synthetic chemistry has long been recognized, methods for their synthesis are still auxiliary‐based approaches which possess disadvantages poor atom economy and limited substrate universality. Due to weak nucleophilicity amides, it is more difficult prepare N‐acylsulfinamides by traditional methods. Herein, we describe an example catalytic asymmetric N‐acyl sulfinamides. In this work, sulfenamides act as useful substrates, because...

10.1002/chir.23478 article EN Chirality 2022-06-09

Hydroxymethylthiohydantoin, hydroxymethylthiohydantoin, and hydantoin, containing a pyridine group, were synthesized to study their androgen receptor antagonistic activities. Among them, compounds

10.3390/molecules27185867 article EN cc-by Molecules 2022-09-10

In this paper, the oxidation mechanism of carbon monoxide (CO) on two-dimensional porphyrin sheet within a single cobalt atom (Co-TDPs) was studied by density functional theory with dispersion (DFT-D). The stability Co-TDPs at different temperatures verified first-principle molecular dynamics simulations. Absorption energies reactant and product to anchor Co–N 4 site showed CO O 2 adsorption be stronger than adsorption. addition, Langmuir–Hinshelwood, Eley–Rideal (ER), ter-molecular (TER)...

10.1142/s179360472251050x article EN Functional Materials Letters 2022-10-01
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